| Health Effects / Bioactivities | | Descriptor | ID | Definition | Reference |
|---|
| Anti-allergic | 50857 | An agent that reduces or blocks allergic reactions, commonly used to manage symptoms of allergies, such as itching, sneezing, and inflammation, by inhibiting the release of histamine and other chemical mediators, providing relief in conditions like hay fever, asthma, and skin allergies. | DUKE | | Anti-anxiety | 52217 | An agent that reduces anxiety symptoms, commonly used in managing anxiety disorders, by modulating neurotransmitters such as GABA and serotonin, promoting relaxation and calming effects, with key medical uses including treatment of generalized anxiety, panic disorders, and social anxiety. | DUKE | | Anti-arrhythmic | 38070 | An agent that regulates heart rhythm, correcting irregular heartbeat patterns. Therapeutically, it restores normal cardiac function, commonly used to manage arrhythmias, prevent sudden cardiac death, and treat conditions like atrial fibrillation and ventricular tachycardia. | DUKE | | Anti-arthritic | 52217 | An agent that reduces joint inflammation and alleviates symptoms of arthritis, commonly used in managing rheumatoid arthritis, osteoarthritis, and other inflammatory joint disorders, to improve mobility and quality of life. | DUKE | | Anti-atherosclerotic | 38070 | An agent that prevents or slows the formation of atherosclerosis, a condition characterized by plaque buildup in arteries. It reduces inflammation, improves lipid profiles, and inhibits platelet aggregation, commonly used to manage cardiovascular diseases, such as coronary artery disease, and prevent heart attacks and strokes. | DUKE | | Anti climacteric | | An agent that alleviates symptoms of male menopause, including reduced libido and sexual activity, by regulating hormonal imbalances, with therapeutic applications in managing andropause and key medical uses in treating age-related sexual dysfunction. | DUKE | | Anti depressant | 52217 | An agent that regulates mood, reducing symptoms of depression and anxiety by altering neurotransmitter levels in the brain, commonly used in managing depression, anxiety disorders, and other mood disorders. | DUKE | | Antidote | 50247 | An agent that counteracts a poison or toxin, neutralizing its harmful effects. It plays a biological role in reversing toxicity, and has therapeutic applications in treating poisoning, overdose, and envenomation. Key medical uses include emergency treatment for snake bites, drug overdose, and chemical exposure. | DUKE | | Anti-hyperkinetic | | An agent that reduces excessive muscular activity, treating abnormal movements, such as tremors, tics, and chorea, with therapeutic applications in managing neurological disorders like Parkinson's disease, Huntington's disease, and dystonia. | DUKE | | Anti hypertensive | 52217 | An agent that lowers blood pressure, reducing the risk of cardiovascular disease. It plays a biological role in relaxing blood vessels, decreasing cardiac workload, and improving blood flow. Therapeutically, it's used to manage hypertension, heart failure, and stroke, with key medical applications in preventing organ damage and improving overall cardiovascular health. | DUKE | | Anti-insomniac | 52217 | An agent that promotes sleep, reducing insomnia symptoms. It regulates the body's sleep-wake cycle, commonly used in managing sleep disorders, such as chronic insomnia, and improving overall sleep quality. | DUKE | | Anti-menopausal | 52217 | An agent that alleviates menopausal symptoms, regulating hormonal balance and reducing discomfort. Therapeutically, it is used to manage hot flashes, night sweats, and mood changes, improving quality of life for menopausal women. Key medical uses include hormone replacement therapy and treatment of menopause-related disorders. | DUKE | | Anti-obesity | 52217 | An agent that reduces body weight, commonly used in managing obesity and related disorders, by regulating appetite, metabolism, and fat storage, with therapeutic applications in preventing chronic diseases such as diabetes and cardiovascular disease. | DUKE | | Anti osteoporotic | 52217 | An agent that prevents or treats osteoporosis by promoting bone density, reducing bone resorption, and increasing calcium absorption, commonly used in managing osteoporosis, osteopenia, and preventing fractures. | DUKE | | Anti periodontitic | | An agent that reduces inflammation of tissue around teeth, preventing gum shrinkage and tooth loosening, commonly used to treat periodontal disease and promote oral health. | DUKE | | Anti premenstrual syndrome | 52217 | An agent that alleviates symptoms of premenstrual syndrome (PMS), reducing physical and emotional discomfort. Its biological role involves regulating hormonal fluctuations, and its therapeutic applications include managing mood swings, bloating, and breast tenderness. Key medical uses include treating PMS, premenstrual dysphoric disorder (PMDD), and other menstrual-related disorders. | DUKE | | Anti-rheumatic | 52217 | An agent that reduces inflammation and alleviates symptoms of rheumatic diseases, such as arthritis. It plays a biological role in modulating the immune system and inhibiting pro-inflammatory pathways. Therapeutically, anti-rheumatics are used to manage conditions like rheumatoid arthritis, lupus, and osteoarthritis, reducing pain, swelling, and joint damage. Key medical uses include slowing disease progression and improving quality of life for patients with chronic rheumatic conditions. | DUKE | | Anti-stress | 52217 | An agent that reduces stress symptoms, commonly used in managing anxiety disorders, promoting relaxation, and mitigating the biological effects of stress on the body, such as hypertension and immune suppression, with therapeutic applications in mental health and key medical uses in cardiology and neurology. | DUKE | | Anti-tic | | An agent that reduces or eliminates tic symptoms, commonly used in managing Tourette's syndrome and other tic disorders, by regulating neurotransmitter activity in the brain, thereby providing therapeutic relief from involuntary movements and vocalizations. | DUKE | | Anxiolytic | 35474 | An agent that reduces anxiety symptoms, commonly used in managing anxiety disorders, such as generalized anxiety disorder and panic disorder, by modulating neurotransmitters like GABA, promoting relaxation and calming effects. | DUKE | | Calcium channel blocker | 38215 | An agent that blocks calcium ion influx, reducing muscle contraction and vascular resistance. Therapeutically, it lowers blood pressure, alleviates angina, and controls certain arrhythmias, commonly used in managing hypertension, coronary artery disease, and cardiac conditions. | DUKE | | Diuretic | 35498 | An agent that increases urine production, helping remove excess fluids and salts from the body. It plays a key biological role in regulating fluid balance and blood pressure. Therapeutically, diuretics are used to treat conditions such as hypertension, edema, and heart failure, helping reduce swelling and lower blood pressure. | DUKE | | Hypocholesterolemic | | An agent that lowers cholesterol levels in the blood, playing a crucial role in preventing cardiovascular disease. Therapeutically, it is used to manage hyperlipidemia and reduce the risk of heart disease, with key medical applications including the treatment of high cholesterol, atherosclerosis, and coronary artery disease. | DUKE | | Hypotensive | | An agent that lowers blood pressure, playing a biological role in regulating cardiovascular function. Therapeutically, it's used to manage hypertension, heart failure, and angina, with key medical applications in preventing stroke, kidney disease, and cardiac complications. | DUKE | | Laxative | 50503 | An agent that stimulates bowel movements, relieving constipation by softening stool or increasing intestinal motility. Therapeutically, laxatives are used to treat constipation, prepare the bowel for medical procedures, and manage certain medical conditions, such as irritable bowel syndrome. | DUKE | | Tranquilizer | | An agent that induces relaxation and reduces anxiety, used therapeutically to manage anxiety disorders, insomnia, and restlessness, promoting calmness and sedation in individuals. | DUKE | | Vasodilator | 35620 | An agent that widens blood vessels, reducing blood pressure and increasing blood flow. It plays a biological role in regulating cardiovascular function. Therapeutically, vasodilators are used to treat conditions such as hypertension, angina, and heart failure, improving oxygen delivery and reducing cardiac workload. | DUKE |
|
|---|
