1.0 2010-04-08 22:06:13 UTC 2025-11-18 22:56:03 UTC FDB004391 2,6-Diemthyl-pyrazine 2,6-Dimethylpyrazine, also known as FEMA 3273 or 2,6-DMP, belongs to the class of organic compounds known as pyrazines. Pyrazines are compounds containing a pyrazine ring, which is a six-member aromatic heterocycle, that consists of two nitrogen atoms (at positions 1 and 4) and four carbon atoms. 2,6-Dimethylpyrazine is also classified as an alkylpyrazine. Alkylpyrazines are naturally occurring highly aromatic substances which often have a very low odor threshold and contribute to the taste and aroma of various foods including coffee and wines. Alkylpyrazines are also formed during the cooking of some foods via Maillard reactions (doi:10.1093/chemse/10.3.287). 2,6-Dimethylpyrazine exists as a white or pale yellow solid. It has a nutty, cocoa, roasted, meaty or coffee-like aroma with a musty, bready or meaty taste. 2,6-Dimethylpyrazine is found naturally in a number of foods and has been detected in black and green tea, whiskey, potato chips, kohlrabi, fenugreek seeds, roasted coffee, bread, beer, baked potato, crispbread, French fries, malt, peated malt, raw asparagus, and roasted barley. 2,6-Dimethylpyrazine is also used as flavor additive and odorant in foods such as cereals and products such as cigarettes. C6H8N2 108.1411 108.068748266 2,6-dimethylpyrazine pyrazine, 2,6-dimethyl- 108-50-9 CC1=CN=CC(C)=N1 InChI=1S/C6H8N2/c1-5-3-7-4-6(2)8-5/h3-4H,1-2H3 HJFZAYHYIWGLNL-UHFFFAOYSA-N belongs to the class of organic compounds known as pyrazines. Pyrazines are compounds containing a pyrazine ring, which is a six-member aromatic heterocycle, that consists of two nitrogen atoms (at positions 1 and 4) and four carbon atoms. Pyrazines Organic compounds Organoheterocyclic compounds Diazines Pyrazines Aromatic heteromonocyclic compounds Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Organonitrogen compounds Organopnictogen compounds Aromatic heteromonocyclic compound Azacycle Heteroaromatic compound Hydrocarbon derivative Organic nitrogen compound Organonitrogen compound Organopnictogen compound Pyrazine logp 0.63 ALOGPS logs 0.23 ALOGPS solubility 1.83e+02 g/l ALOGPS logp -0.2 ChemAxon pka_strongest_basic 2.14 ChemAxon iupac 2,6-dimethylpyrazine ChemAxon average_mass 108.1411 ChemAxon mono_mass 108.068748266 ChemAxon smiles CC1=CN=CC(C)=N1 ChemAxon formula C6H8N2 ChemAxon inchi InChI=1S/C6H8N2/c1-5-3-7-4-6(2)8-5/h3-4H,1-2H3 ChemAxon inchikey HJFZAYHYIWGLNL-UHFFFAOYSA-N ChemAxon polar_surface_area 25.78 ChemAxon refractivity 30.93 ChemAxon polarizability 11.87 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 1536 Specdb::CMs 3289 Specdb::CMs 172995 Specdb::MsIr 6888 Specdb::MsIr 6889 Specdb::MsMs 98019 Specdb::MsMs 98020 Specdb::MsMs 98021 Specdb::MsMs 162843 Specdb::MsMs 162844 Specdb::MsMs 162845 Specdb::MsMs 2391805 Specdb::MsMs 2391806 Specdb::MsMs 2391807 Specdb::MsMs 2570801 Specdb::MsMs 2570802 Specdb::MsMs 2570803 Specdb::NmrOneD 3785 Specdb::NmrOneD 4044 Specdb::NmrOneD 130718 Specdb::NmrOneD 130719 Specdb::NmrOneD 130720 Specdb::NmrOneD 130721 Specdb::NmrOneD 130722 Specdb::NmrOneD 130723 Specdb::NmrOneD 130724 Specdb::NmrOneD 130725 Specdb::NmrOneD 130726 Specdb::NmrOneD 130727 Specdb::NmrOneD 130728 Specdb::NmrOneD 130729 Specdb::NmrOneD 130730 Specdb::NmrOneD 130731 Specdb::NmrOneD 130732 Specdb::NmrOneD 130733 Specdb::NmrOneD 130734 Specdb::NmrOneD 130735 Specdb::NmrOneD 130736 Specdb::NmrOneD 130737 HMDB0035248 Black tea Type 1 Green tea Type 1 Herbal tea Type 1 Red tea Type 1 Tea Type 1 specific Camellia sinensis 4442 cocoa roastbeef roastednut