1.0 2010-04-08 22:06:39 UTC 2019-11-26 03:00:31 UTC FDB005352 Tetrahydrocurcumin Tetrahydrocurcumin (THC), one of the major metabolites of curcumin, exhibits many of the same physiologic and pharmacological activities as curcumin and in some systems may exert greater antioxidant activity than curcumin (PMID: 16061427). Tetrahydrocurcumin is found in turmeric. 1,7-bis(4-hydroxy-3-methoxyphenyl)-3,5-Heptanedione 3,5-Heptanedione, 1,7-bis(4-hydroxy-3-methoxyphenyl)- C21H24O6 372.4117 372.1572885 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione tetrahydrocurcumin 36062-04-1 COC1=CC(CCC(=O)CC(=O)CCC2=CC(OC)=C(O)C=C2)=CC=C1O InChI=1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3 LBTVHXHERHESKG-UHFFFAOYSA-N belongs to the class of organic compounds known as curcuminoids. These are aromatic compounds containing a curcumin moiety, which is composed of two aryl buten-2-one (feruloyl) chromophores joined by a methylene group. Curcuminoids Organic compounds Phenylpropanoids and polyketides Diarylheptanoids Linear diarylheptanoids Aromatic homomonocyclic compounds 1-hydroxy-2-unsubstituted benzenoids Alkyl aryl ethers Anisoles Beta-diketones Gingerdiones Hydrocarbon derivatives Ketones Methoxybenzenes Organic oxides Phenoxy compounds 1,3-dicarbonyl compound 1,3-diketone 1-hydroxy-2-unsubstituted benzenoid Alkyl aryl ether Anisole Aromatic homomonocyclic compound Benzenoid Carbonyl group Curcumin Ether Gingerdione Hydrocarbon derivative Ketone Methoxybenzene Methoxyphenol Monocyclic benzene moiety Organic oxide Organic oxygen compound Organooxygen compound Phenol Phenol ether Phenoxy compound beta-diketone diarylheptanoid polyphenol Solid logp 3.51 ALOGPS logs -4.82 ALOGPS solubility 5.63e-03 g/l ALOGPS melting_point 95-97 oC logp 3.96 ChemAxon pka_strongest_acidic 9.31 ChemAxon pka_strongest_basic -4.6 ChemAxon iupac 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione ChemAxon average_mass 372.4117 ChemAxon mono_mass 372.1572885 ChemAxon smiles COC1=CC(CCC(=O)CC(=O)CCC2=CC(OC)=C(O)C=C2)=CC=C1O ChemAxon formula C21H24O6 ChemAxon inchi InChI=1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3 ChemAxon inchikey LBTVHXHERHESKG-UHFFFAOYSA-N ChemAxon polar_surface_area 93.06 ChemAxon refractivity 101.62 ChemAxon polarizability 39.42 ChemAxon rotatable_bond_count 10 ChemAxon acceptor_count 6 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 22739 Specdb::CMs 38888 Specdb::CMs 137021 Specdb::CMs 144755 Specdb::MsMs 29627 Specdb::MsMs 29628 Specdb::MsMs 29629 Specdb::MsMs 36185 Specdb::MsMs 36186 Specdb::MsMs 36187 Specdb::MsMs 2308344 Specdb::MsMs 2308345 Specdb::MsMs 2308346 Specdb::MsMs 2653766 Specdb::MsMs 2653767 Specdb::MsMs 2653768 Specdb::NmrOneD 293355 Specdb::NmrOneD 293356 Specdb::NmrOneD 293357 Specdb::NmrOneD 293358 Specdb::NmrOneD 293359 Specdb::NmrOneD 293360 Specdb::NmrOneD 293361 Specdb::NmrOneD 293362 Specdb::NmrOneD 293363 Specdb::NmrOneD 293364 Specdb::NmrOneD 293365 Specdb::NmrOneD 293366 Specdb::NmrOneD 293367 Specdb::NmrOneD 293368 Specdb::NmrOneD 293369 Specdb::NmrOneD 293370 Specdb::NmrOneD 293371 Specdb::NmrOneD 293372 Specdb::NmrOneD 293373 Specdb::NmrOneD 293374 HMDB05789 #<Reference:0x000055ce3350d848> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Turmeric Type 1 specific Curcuma longa 136217 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Anti aflatoxin 92 A substance that diminishes the rate of a chemical reaction. Anti-inflammatory 370 A substance that reduces or suppresses inflammation. Anti-oxidant 502 A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. Antitumor promoter 673 A substance that inhibits or prevents the proliferation of neoplasms.