1.0 2010-04-08 22:06:47 UTC 2025-11-18 22:59:43 UTC FDB005663 Uricase Uricase is also known as oxidase, urate or urate oxidase. Uricase can be found in soy bean, which makes uricase a potential biomarker for the consumption of this food product. The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 5-hydroxyisourate + H2O → allantoin + CO2 . Aspergilus urate oxidase Rasburicase Urate oxidase Urate: oxygen oxoreductase Urate:O2 oxidoreductase Uricase bacillus fastidiosus Uricase from arthrobacter globiformis Uricase from candida SP. C18H26N5O14P 567.3979 567.121387077 {[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy})phosphinic acid amine [5-(2,4-dioxo-3H-pyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy[5-(2,4-dioxo-3H-pyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyphosphinic acid amine 9002-12-4 N.OCC1OC(C(O)C1OP(O)(=O)OCC1OC(C(O)C1O)N1C=CC(=O)NC1=O)N1C=CC(=O)NC1=O InChI=1S/C18H23N4O14P.H3N/c23-5-7-14(13(28)16(34-7)22-4-2-10(25)20-18(22)30)36-37(31,32)33-6-8-11(26)12(27)15(35-8)21-3-1-9(24)19-17(21)29;/h1-4,7-8,11-16,23,26-28H,5-6H2,(H,31,32)(H,19,24,29)(H,20,25,30);1H3 VPXDHZMLJOJKOX-UHFFFAOYSA-N belongs to the class of organic compounds known as (3'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (3'->5')-phosphodiester linkage. (3'->5')-dinucleotides Organic compounds Nucleosides, nucleotides, and analogues (3'->5')-dinucleotides and analogues (3'->5')-dinucleotides Aromatic heteromonocyclic compounds Azacyclic compounds Dialkyl phosphates Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Lactams Monosaccharide phosphates Organic oxides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Pentose phosphates Primary alcohols Pyrimidine ribonucleoside monophosphates Pyrimidones Ribonucleoside 3'-phosphates Secondary alcohols Tetrahydrofurans Ureas Vinylogous amides (3'->5')-dinucleotide Alcohol Alkyl phosphate Aromatic heteromonocyclic compound Azacycle Dialkyl phosphate Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Lactam Monosaccharide Monosaccharide phosphate N-glycosyl compound Organic nitrogen compound Organic oxide Organic oxygen compound Organic phosphoric acid derivative Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pentose phosphate Pentose-5-phosphate Phosphoric acid ester Primary alcohol Pyrimidine Pyrimidine ribonucleoside monophosphate Pyrimidone Ribonucleoside 3'-phosphate Secondary alcohol Tetrahydrofuran Urea Vinylogous amide logp -4.1 ChemAxon pka_strongest_acidic 1.83 ChemAxon pka_strongest_basic -3 ChemAxon iupac {[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy})phosphinic acid amine ChemAxon average_mass 567.3979 ChemAxon mono_mass 567.121387077 ChemAxon smiles N.OCC1OC(C(O)C1OP(O)(=O)OCC1OC(C(O)C1O)N1C=CC(=O)NC1=O)N1C=CC(=O)NC1=O ChemAxon formula C18H26N5O14P ChemAxon inchi InChI=1S/C18H23N4O14P.H3N/c23-5-7-14(13(28)16(34-7)22-4-2-10(25)20-18(22)30)36-37(31,32)33-6-8-11(26)12(27)15(35-8)21-3-1-9(24)19-17(21)29;/h1-4,7-8,11-16,23,26-28H,5-6H2,(H,31,32)(H,19,24,29)(H,20,25,30);1H3 ChemAxon inchikey VPXDHZMLJOJKOX-UHFFFAOYSA-N ChemAxon polar_surface_area 253.96 ChemAxon refractivity 112.23 ChemAxon polarizability 47.01 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 12 ChemAxon donor_count 7 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 88494 Specdb::MsMs 88495 Specdb::MsMs 88496 Specdb::MsMs 151233 Specdb::MsMs 151234 Specdb::MsMs 151235 Soy bean Type 1 specific Glycine max 3847