1.0 2010-04-08 22:06:51 UTC 2025-11-18 23:00:10 UTC FDB005824 2-Hydroxy-4-methoxybenzaldehyde 2-hydroxy-4-methoxybenzaldehyde, also known as 4-methoxysalicylaldehyde or 2-hydroxy-P-anisaldehyde, is a member of the class of compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. 2-hydroxy-4-methoxybenzaldehyde is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 2-hydroxy-4-methoxybenzaldehyde is a vanillin tasting compound found in black walnut, which makes 2-hydroxy-4-methoxybenzaldehyde a potential biomarker for the consumption of this food product. 2-hydroxy-4-methoxybenzaldehyde is a chemical compound and an isomer of vanillin. Urolithin M7, one of the urolithins, has also been synthesized from 2-hydroxy-4-methoxybenzaldehyde using the inverse electron-demand Diels–Alder reaction . 2-Hydroxy-4-methoxybenzaldehyde 2-Hydroxy-p-anisaldehyde 4-Methoxysalicyaldehyde 4-Methoxysalicylaldehyde 4-o-methylresorcylaldehyde Benzaldehyde, 2-hydroxy-4-methoxy- ghl.PD_Mitscher_leg0.298 O-hydroxy-p-methoxybenzaldehyde p-Anisaldehyde, 2-hydroxy- Salicylaldehyde, 4-methoxy- C8H8O3 152.1473 152.047344122 2-hydroxy-4-methoxybenzaldehyde 2-hydroxy-4-methoxybenzaldehyde 673-22-3 COC1=CC(O)=C(C=O)C=C1 InChI=1S/C8H8O3/c1-11-7-3-2-6(5-9)8(10)4-7/h2-5,10H,1H3 WZUODJNEIXSNEU-UHFFFAOYSA-N belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. Methoxyphenols Organic compounds Benzenoids Phenols Methoxyphenols Aromatic homomonocyclic compounds 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Alkyl aryl ethers Anisoles Benzoyl derivatives Hydrocarbon derivatives Hydroxybenzaldehydes Methoxybenzenes Organic oxides Phenoxy compounds Vinylogous acids 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid Aldehyde Alkyl aryl ether Anisole Aromatic homomonocyclic compound Aryl-aldehyde Benzaldehyde Benzoyl Ether Hydrocarbon derivative Hydroxybenzaldehyde Methoxybenzene Methoxyphenol Monocyclic benzene moiety Organic oxide Organic oxygen compound Organooxygen compound Phenol ether Phenoxy compound Vinylogous acid logp 1.31 ALOGPS logs -1.47 ALOGPS solubility 5.19e+00 g/l ALOGPS logp 1.87 ChemAxon pka_strongest_acidic 8.31 ChemAxon pka_strongest_basic -4.8 ChemAxon iupac 2-hydroxy-4-methoxybenzaldehyde ChemAxon average_mass 152.1473 ChemAxon mono_mass 152.047344122 ChemAxon smiles COC1=CC(O)=C(C=O)C=C1 ChemAxon formula C8H8O3 ChemAxon inchi InChI=1S/C8H8O3/c1-11-7-3-2-6(5-9)8(10)4-7/h2-5,10H,1H3 ChemAxon inchikey WZUODJNEIXSNEU-UHFFFAOYSA-N ChemAxon polar_surface_area 46.53 ChemAxon refractivity 41.09 ChemAxon polarizability 14.87 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 90761 Specdb::MsMs 95955 Specdb::MsMs 95956 Specdb::MsMs 95957 Specdb::MsMs 160338 Specdb::MsMs 160339 Specdb::MsMs 160340 Black walnut Type 1 specific Juglans nigra 16719 2400.0 2400.0 2400.0 mg/100 g vanillin