Record Information
Version1.0
Creation date2010-04-08 22:07:16 UTC
Update date2020-09-17 15:35:05 UTC
Primary IDFDB006725
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameDimethyl sulfone
DescriptionDimethyl sulfone (DMSO2), also known as sulfonylbismethane, belongs to the class of organic compounds known as sulfones. Sulfones are compounds containing a sulfonyl group, with the general structure RS(=O)2R' (R,R' =alkyl, aryl). It occurs naturally in some primitive plants and is present in small amounts in many foods and beverages and it is marketed as a dietary supplement. This colorless solid features a sulfonyl functional group and is considered relatively inert chemically. Dimethyl sulfone reflects its close chemical relationship to dimethyl sulfoxide (DMSO), which differs only in the oxidation state of the sulfur atom. Dimethyl sulfone is the primary metabolite of DMSO in humans, and it shares some of the properties of DMSO. Dimethyl sulfone is a metabolite occurring in plasma and cerebrospinal fluid of normal humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism (PMID: 15996001). It is sometimes used as a cutting agent for illicitly manufactured methamphetamine. Because of its polarity and thermal stability, Dimethyl sulfone is used industrially as a high-temperature solvent for both inorganic and organic substances. Dimethyl sulfone is also commonly found in the atmosphere above marine areas, where it is used as a carbon source by the airborne bacteria Afipia (PMID: 23359712).
CAS Number67-71-0
Structure
Thumb
Synonyms
SynonymSource
(Methylsulfonyl)methaneHMDB
Dimethyl sulfonebiospider
Dimethyl sulphonebiospider
Dimethylsulfonebiospider
DMSO2manual
Lignisul msmHMDB
Methane, 1,1'-sulfonylbis-biospider
Methane, sulfonylbis-biospider
Methyl sulfonebiospider
Methylsulfonyl methanebiospider
Methylsulfonylmethanebiospider
MethylsulphonylmethaneGenerator
MSMbiospider
Opti msmHMDB
Sulfone, dimethyl-biospider
Sulfonylbis-methaneHMDB
Sulfonylbismethanebiospider
Sulfonyldimethanebiospider
Sulphonylbismethanebiospider
Predicted PropertiesNot Available
Chemical FormulaC2H6O2S
IUPAC name
InChI IdentifierInChI=1S/C2H6O2S/c1-5(2,3)4/h1-2H3
InChI KeyHHVIBTZHLRERCL-UHFFFAOYSA-N
Isomeric SMILESCS(C)(=O)=O
Average Molecular Weight94.133
Monoisotopic Molecular Weight94.008850126
Classification
ClassificationNot classified
Ontology
Disposition

Route of exposure:

Source:

Biological location:

Role

Biological role:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateSolid
Physical DescriptionNot Available
Mass CompositionNot Available
Melting Point109 oC
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logP-1.41HANSCH,C ET AL. (1995)
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
EI-MS/GC-MSNot Available
MS/MSNot Available
NMRNot Available
ChemSpider ID5978
ChEMBL IDCHEMBL25028
KEGG Compound IDC11142
Pubchem Compound ID6213
Pubchem Substance IDNot Available
ChEBI ID9349
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB04983
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDDIMETHYL-SULFONE
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet ID67-71-0
GoodScent IDrw1260371
SuperScent IDNot Available
Wikipedia IDMethylsulfonylmethane
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
Flavours
FlavorCitations
sulfur
  1. Arn, H, Acree TE. “Flavornet: A database of aroma compounds based on odor potency in natural products”. Developments in Food Science 40 (1998): 27. doi:10.1016/S0167-4501(98)80029-0
burnt
  1. Arn, H, Acree TE. “Flavornet: A database of aroma compounds based on odor potency in natural products”. Developments in Food Science 40 (1998): 27. doi:10.1016/S0167-4501(98)80029-0
  2. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
sulfurous
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
Files
MSDSshow
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference— Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004).