1.0 2010-04-08 22:07:27 UTC 2019-11-26 03:01:29 UTC FDB007103 Diazepam Diazepam, first marketed as Valium by Hoffmann-La Roche, is a benzodiazepine derivative drug. It is commonly used for treating anxiety, insomnia, seizures including status epilepticus, muscle spasms (such as in cases of tetanus), restless legs syndrome, alcohol withdrawal, benzodiazepine withdrawal and Ménière's disease. Diazepam is found in potato and common wheat. 7-Chloro-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepine 7-Chloro-1-methyl-5-3H-1,4-benzodiazepin-2(1H)-one 7-Chloro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one 7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one 7-chloro-1,3-dihydro-1-Methyl-5-phenyl-2H-1,4-benzodiazepin-2-one Alboral Aliseum Alupram Amiprol An-ding Ansilive Ansiolin Ansiolisina Antenex Anxicalm Anxionil Apaurin Apo-diazepam Apozepam Armonil Arzepam Assival Atensine Atilen Azedipamin Baogin Bensedin Benzopin Best Betapam Bialzepam Britazepam Calmaven Calmocitene Calmod Calmpose Caudel Centrazepam Cercine Ceregulart Chuansuan Desconet Desloneg Diacepan Diaceplex Dialag Dialar Diapam Diapax Diapine Diaquel Diastat Diatran Diazapam Diazem Diazepin Dipam Dipaz Dipezona Disopam Dizac Doval Drenian Ducene Duksen Dupin Duxen Eridan Euphorin p Eurosan Evacalm Faustal Faustan Gewacalm Gradual Gubex Horizon Jinpanfan Kratium Lamra Lembrol Levium Lovium Mandro Mandrozep Mentalium Methyl diazepinone Methyldiazepinone Morosan Nellium Nerozen Nivalen Nixtensyn Notense Novazam Pacitran Paralium Parzam Pax Paxate Paxel Paxum Placidox 10 Placidox 2 Placidox 5 Plidan Pomin Propam Prozepam Psychopax Q-Pam Quievita Radizepam Relanium Reliver Saromet Sedapam Seduksen Seduxen Serenack Serenamin Serenzin Servizepam Setonil Sibazon Sibazone Simasedan Sipam Solis Sonacon Stesolid Stesolin Tensium Tensopam Tranimul Trankinon Tranquirit Trazepam Umbrium Unisedil Valaxona Valeo Valiquid Valitran Valium Valrelease Valuzepam Vanconin Vatran Vazen Vazepam Velium Vival Vivol Winii Zepaxid Zipan C16H13ClN2O 284.74 284.071640755 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one diazepam 439-14-5 CN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1 InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 AAOVKJBEBIDNHE-UHFFFAOYSA-N belongs to the class of organic compounds known as 1,4-benzodiazepines. These are organic compounds containing a benzene ring fused to a 1,4-azepine. 1,4-benzodiazepines Organic compounds Organoheterocyclic compounds Benzodiazepines 1,4-benzodiazepines Aromatic heteropolycyclic compounds Alpha amino acids and derivatives Aryl chlorides Azacyclic compounds Benzene and substituted derivatives Carbonyl compounds Hydrocarbon derivatives Ketimines Lactams Organic oxides Organochlorides Organopnictogen compounds Propargyl-type 1,3-dipolar organic compounds Tertiary carboxylic acid amides 1,4-benzodiazepine Alpha-amino acid or derivatives Aromatic heteropolycyclic compound Aryl chloride Aryl halide Azacycle Benzenoid Carbonyl group Carboxamide group Carboxylic acid derivative Hydrocarbon derivative Imine Ketimine Lactam Monocyclic benzene moiety Organic 1,3-dipolar compound Organic nitrogen compound Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Propargyl-type 1,3-dipolar organic compound Tertiary carboxylic acid amide 1,4-benzodiazepinone organochlorine compound Solid logp 2.63 ALOGPS logs -4.37 ALOGPS solubility 1.22e-02 g/l ALOGPS melting_point 132 oC logp 3.08 ChemAxon pka_strongest_basic 2.92 ChemAxon iupac 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one ChemAxon average_mass 284.74 ChemAxon mono_mass 284.071640755 ChemAxon smiles CN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1 ChemAxon formula C16H13ClN2O ChemAxon inchi InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 ChemAxon inchikey AAOVKJBEBIDNHE-UHFFFAOYSA-N ChemAxon polar_surface_area 32.67 ChemAxon refractivity 79.81 ChemAxon polarizability 29.39 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 1337 Specdb::CMs 23477 Specdb::CMs 27435 Specdb::CMs 27607 Specdb::CMs 27708 Specdb::CMs 100193 Specdb::CMs 100194 Specdb::CMs 100195 Specdb::CMs 168830 Specdb::MsMs 79419 Specdb::MsMs 79420 Specdb::MsMs 79421 Specdb::MsMs 140010 Specdb::MsMs 140011 Specdb::MsMs 140012 Specdb::MsMs 441152 Specdb::MsMs 441153 Specdb::MsMs 441154 Specdb::MsMs 441155 Specdb::MsMs 442603 Specdb::MsMs 442604 Specdb::MsMs 442605 Specdb::MsMs 442606 Specdb::MsMs 442607 Specdb::MsMs 442608 Specdb::MsMs 442609 Specdb::MsMs 442610 Specdb::MsMs 442611 Specdb::MsMs 442612 Specdb::MsMs 442613 Specdb::MsMs 442614 Specdb::MsMs 442615 Specdb::MsMs 442616 Specdb::MsMs 448920 HMDB14967 4494 DZP #<Reference:0x000055ce32adc1f8> #<Reference:0x000055ce32adc040> #<Reference:0x000055ce32adbe38> #<Reference:0x000055ce32adbc80> #<Reference:0x000055ce32adbac8> Common wheat Type 1 specific Triticum aestivum 4565 Potato Type 1 specific Solanum tuberosum 4113 Amnesigenic 49 A role played by the molecular entity or part thereof which causes the development of a pathological process. Anesthetic 62 Anti convulsant 204 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti epileptic 265 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti tetanic 643 A substance that kills or slows the growth of bacteria. Anti-alcoholic 98 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-anorectic 117 An agent which regulates the physiologic mechanisms that control the appetite and food intake. Anti-myocarditic 459 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Anti-schizophrenic 594 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-torticollic 662 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anxiolytic 698 Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. Myorelaxant 1134 Sedative 1311 A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.