1.0 2010-04-08 22:08:17 UTC 2025-11-18 23:14:22 UTC FDB008862 2-Methoxy-4-methylphenol 4-Methyl Guaiacol or 2-Methoxy-4-methylphenol, also known creosol, belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. 4-Methyl guaiacol or Creosol is a chemical compound with the molecular formula C8H10O2. Creosol reacts with hydrogen halides to give a catechol. It is one of the components of creosote. 4-Methyl Guaiacol is a bacon, bitter, and carnation tasting compound. 4-Methyl guaiacol has been detected, but not quantified, in several different foods, such as red bell peppers, green bell peppers, orange bell peppers, corns, and pepper (c. annuum). Sources of creosol include: Coal tar, creosote wood, creosote reduction, it can be a product of vanillin using zinc powder in strong hydrochloric acid. It can be found as glycosides in green vanilla beans. It is also found in tequila. Compared with phenol, creosol is a less toxic disinfectant. 1-Hydroxy-2-methoxy-4-methylbenzene 2-Hydroxy-5-methylanisole 2-Methoxy-4-cresol 2-Methoxy-4-methyl-phenol 2-Methoxy-4-methylphenol (4-methylguaiacol) 2-methoxy-4-methylphenol (creosol) 2-Methoxy-4-methylphenol, 9CI 2-Methoxy-p-cresol 3-Methoxy-4-hydroxytoluene 3-Methoxy-4-methyl-phenol 4-Hydroxy-3-methoxy-1-methylbenzene 4-Hydroxy-3-methoxytoluene 4-Methyl guaiacol 4-Methyl-2-methoxyphenol 4-Methyl-2-methoxyphenol (4-methylguaiacol) 4-Methylguaiacol 5-Methylguaiacol Creosol Cresolum drudum FEMA 2671 Homocatechol methyl ester Homocatechol monomethyl ether Homoguaiacol Kreosol P-creosol p-Cresol, 2-methoxy- P-methylguaiacol P-methylguaicol Phenol, 2-methoxy-4-methyl- Phenol, 3-methoxy-4-methyl- Phenol, 4-methyl-2-methoxy Rohkcrsol Valspice C8H10O2 138.1638 138.068079564 2-methoxy-4-methylphenol creosol 93-51-6 COC1=C(O)C=CC(C)=C1 InChI=1S/C8H10O2/c1-6-3-4-7(9)8(5-6)10-2/h3-5,9H,1-2H3 PETRWTHZSKVLRE-UHFFFAOYSA-N belongs to the class of organic compounds known as methoxyphenols. Methoxyphenols are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. Methoxyphenols Organic compounds Benzenoids Phenols Methoxyphenols Aromatic homomonocyclic compounds 1-hydroxy-2-unsubstituted benzenoids Alkyl aryl ethers Anisoles Hydrocarbon derivatives Methoxybenzenes Para cresols Phenoxy compounds Toluenes 1-hydroxy-2-unsubstituted benzenoid Alkyl aryl ether Anisole Aromatic homomonocyclic compound Ether Hydrocarbon derivative Methoxybenzene Methoxyphenol Monocyclic benzene moiety Organic oxygen compound Organooxygen compound P-cresol Phenol ether Phenoxy compound Toluene Liquid logp 1.79 ALOGPS logs -1.31 ALOGPS solubility 6.71e+00 g/l ALOGPS melting_point Mp 5.5° logp 2.03 ChemAxon pka_strongest_acidic 10.34 ChemAxon pka_strongest_basic -4.9 ChemAxon iupac 2-methoxy-4-methylphenol ChemAxon average_mass 138.1638 ChemAxon mono_mass 138.068079564 ChemAxon smiles COC1=C(O)C=CC(C)=C1 ChemAxon formula C8H10O2 ChemAxon inchi InChI=1S/C8H10O2/c1-6-3-4-7(9)8(5-6)10-2/h3-5,9H,1-2H3 ChemAxon inchikey PETRWTHZSKVLRE-UHFFFAOYSA-N ChemAxon polar_surface_area 29.46 ChemAxon refractivity 39.54 ChemAxon polarizability 14.77 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 1868 Specdb::CMs 17153 Specdb::CMs 29173 Specdb::CMs 42768 Specdb::CMs 101072 Specdb::CMs 136201 Specdb::CMs 143935 Specdb::MsIr 5114 Specdb::MsIr 5115 Specdb::MsIr 5116 Specdb::NmrOneD 3999 Specdb::NmrOneD 4287 Specdb::NmrOneD 111998 Specdb::NmrOneD 111999 Specdb::NmrOneD 112000 Specdb::NmrOneD 112001 Specdb::NmrOneD 112002 Specdb::NmrOneD 112003 Specdb::NmrOneD 112004 Specdb::NmrOneD 112005 Specdb::NmrOneD 112006 Specdb::NmrOneD 112007 Specdb::NmrOneD 112008 Specdb::NmrOneD 112009 Specdb::NmrOneD 112010 Specdb::NmrOneD 112011 Specdb::NmrOneD 112012 Specdb::NmrOneD 112013 Specdb::NmrOneD 112014 Specdb::NmrOneD 112015 Specdb::NmrOneD 112016 Specdb::NmrOneD 112017 Specdb::MsMs 88257 Specdb::MsMs 88258 Specdb::MsMs 88259 Specdb::MsMs 150951 Specdb::MsMs 150952 Specdb::MsMs 150953 Specdb::MsMs 2752030 Specdb::MsMs 2752031 Specdb::MsMs 2752032 Specdb::MsMs 2929419 Specdb::MsMs 2929420 Specdb::MsMs 2929421 HMDB32136 #<Reference:0x000055ce3306cf78> Anise Type 1 specific Pimpinella anisum 271192 Corn Type 1 specific Zea mays 4577 Green bell pepper Type 1 specific Capsicum annuum 4072 Orange bell pepper Type 1 specific Capsicum annuum 4072 Pepper Type 1 specific Capsicum annuum 4072 Red bell pepper Type 1 specific Capsicum annuum 4072 White wine Type 2 0.087 0.087 0.087 mg/100 g Yellow bell pepper Type 1 specific Capsicum annuum 4072 bacon bitter carnation clove leather medical medicinal mesquite phenolic smoky spice vanilla