1.0 2010-04-08 22:08:17 UTC 2025-11-18 23:14:25 UTC FDB008865 1,2-Dimethoxybenzene O-dimethyl hydroquinone or 1,2-dimethoxybenzene commonly known as veratrole, is a chemical compound with the formula C6H4(OCH3)2. It is the dimethyl ether derived from pyrocatechol. It is one of three isomers of dimethoxybenzene. Veratrole is a colorless liquid, with a pleasant odor and slightly soluble in water, but miscible in all organic solvents. It is found in raw and cooked foods, such as cheeses, grapes, corn and asparagus. Veratrole is a food additive listed in the EAFUS food Additive Database (Jan 2001). It is a building block for the organic synthesis of other aromatic compounds. Veratrole is relatively electron-rich and thus readily undergoes electrophilic substitution. 2-Dimethoxybenzol 2-Methoxyanisole Benzene, o-dimethoxy- Catechol dimethyl ether FEMA 3799 Guaiacol methylether Methyl guaiacol O-Dimethoxy-benzene O-Dimethoxybenzene o,o-Dimethyl catechol Orthodimethoxybenzene Pyrocatechol dimethyl ether Synthol Veratrol Veratrole C8H10O2 138.1638 138.068079564 1,2-dimethoxybenzene veratrole 91-16-7 COC1=CC=CC=C1OC InChI=1S/C8H10O2/c1-9-7-5-3-4-6-8(7)10-2/h3-6H,1-2H3 ABDKAPXRBAPSQN-UHFFFAOYSA-N belongs to the class of organic compounds known as dimethoxybenzenes. These are organic aromatic compounds containing a monocyclic benzene moiety carrying exactly two methoxy groups. Dimethoxybenzenes Organic compounds Benzenoids Benzene and substituted derivatives Methoxybenzenes Aromatic homomonocyclic compounds Alkyl aryl ethers Anisoles Hydrocarbon derivatives Phenoxy compounds Alkyl aryl ether Anisole Aromatic homomonocyclic compound Dimethoxybenzene Ether Hydrocarbon derivative O-dimethoxybenzene Organic oxygen compound Organooxygen compound Phenol ether Phenoxy compound dimethoxybenzene Liquid logp 2.10 ALOGPS logs -1.99 ALOGPS solubility 1.42e+00 g/l ALOGPS melting_point Mp 22.5° logp 1.66 ChemAxon pka_strongest_basic -4.6 ChemAxon iupac 1,2-dimethoxybenzene ChemAxon average_mass 138.1638 ChemAxon mono_mass 138.068079564 ChemAxon smiles COC1=CC=CC=C1OC ChemAxon formula C8H10O2 ChemAxon inchi InChI=1S/C8H10O2/c1-9-7-5-3-4-6-8(7)10-2/h3-6H,1-2H3 ChemAxon inchikey ABDKAPXRBAPSQN-UHFFFAOYSA-N ChemAxon polar_surface_area 18.46 ChemAxon refractivity 38.98 ChemAxon polarizability 14.65 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 1630 Specdb::MsIr 5122 Specdb::MsIr 5123 Specdb::CMs 2716 Specdb::CMs 27698 Specdb::CMs 28750 Specdb::CMs 28785 Specdb::CMs 28991 Specdb::CMs 29186 Specdb::CMs 29708 Specdb::CMs 101074 Specdb::CMs 101075 Specdb::CMs 101076 Specdb::CMs 101077 Specdb::CMs 101078 Specdb::CMs 101079 Specdb::CMs 153092 Specdb::MsMs 75450 Specdb::MsMs 75451 Specdb::MsMs 75452 Specdb::MsMs 135087 Specdb::MsMs 135088 Specdb::MsMs 135089 Specdb::MsMs 1478528 Specdb::MsMs 1478529 Specdb::MsMs 1478530 Specdb::MsMs 1478531 Specdb::MsMs 1478532 Specdb::MsMs 1478533 Specdb::MsMs 1478534 Specdb::MsMs 1478535 Specdb::MsMs 1478536 Specdb::MsMs 1478537 Specdb::MsMs 1478538 Specdb::MsMs 1478539 Specdb::MsMs 1478540 Specdb::MsMs 1478541 Specdb::MsMs 1478542 Specdb::MsMs 1478543 Specdb::MsMs 1478544 Specdb::MsMs 1478545 Specdb::MsMs 1478546 Specdb::NmrOneD 3996 Specdb::NmrOneD 4284 Specdb::NmrOneD 112038 Specdb::NmrOneD 112039 Specdb::NmrOneD 112040 Specdb::NmrOneD 112041 Specdb::NmrOneD 112042 Specdb::NmrOneD 112043 Specdb::NmrOneD 112044 Specdb::NmrOneD 112045 Specdb::NmrOneD 112046 Specdb::NmrOneD 112047 Specdb::NmrOneD 112048 Specdb::NmrOneD 112049 Specdb::NmrOneD 112050 Specdb::NmrOneD 112051 Specdb::NmrOneD 112052 Specdb::NmrOneD 112053 Specdb::NmrOneD 112054 Specdb::NmrOneD 112055 Specdb::NmrOneD 112056 Specdb::NmrOneD 112057 HMDB32139 #<Reference:0x000055ce317cc9a0> #<Reference:0x000055ce317cc7e8> Asparagus Type 1 specific Asparagus officinalis 4686 Black tea Type 1 Blackberry Type 1 specific Rubus Broccoli Type 1 specific Brassica oleracea var. italica 36774 Cauliflower Type 1 specific Brassica oleracea var. botrytis 3715 Corn Type 1 specific Zea mays 4577 Evergreen blackberry Type 1 specific Rubus laciniatus Fruits Unknown generic Green tea Type 1 Green vegetables Unknown generic Herbal tea Type 1 Milk and milk products Unknown generic Red tea Type 1 Tea Type 1 specific Camellia sinensis 4442 creamy musty phenolic sweet vanilla