1.0 2010-04-08 22:09:09 UTC 2025-11-18 23:19:39 UTC FDB010503 4'-Hydroxyacetophenone 4'-hydroxyacetophenone, also known as (4-hydroxyphenyl)ethan-1-one or 4-acetylphenol, is a member of the class of compounds known as alkyl-phenylketones. Alkyl-phenylketones are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group. 4'-hydroxyacetophenone is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). 4'-hydroxyacetophenone is a mild, sweet, and balsam tasting compound found in sweet orange, which makes 4'-hydroxyacetophenone a potential biomarker for the consumption of this food product. 1-(4-Hydroxyphenyl)ethanone, 9CI 4-Acetylphenol 4-Hydroxyacetophenone 4-Hydroxyphenyl methyl ketone Ameliarol Ethanone, 1-(4-hydroxyphenyl)- Methyl p-hydroxyphenyl ketone p-Acetylphenol p-Hydroxyacetophenone p-Hydroxyphenyl methyl ketone p-Oxyacetophenone para-Hydroxyacetophenone Piceol C8H8O2 136.1479 136.0524295 1-(4-hydroxyphenyl)ethan-1-one 4-hydroxyacetophenone 99-93-4 CC(=O)C1=CC=C(O)C=C1 InChI=1S/C8H8O2/c1-6(9)7-2-4-8(10)5-3-7/h2-5,10H,1H3 TXFPEBPIARQUIG-UHFFFAOYSA-N belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group. Alkyl-phenylketones Organic compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Aromatic homomonocyclic compounds 1-hydroxy-2-unsubstituted benzenoids Acetophenones Aryl alkyl ketones Benzoyl derivatives Hydrocarbon derivatives Organic oxides 1-hydroxy-2-unsubstituted benzenoid Acetophenone Alkyl-phenylketone Aromatic homomonocyclic compound Aryl alkyl ketone Benzenoid Benzoyl Hydrocarbon derivative Monocyclic benzene moiety Organic oxide Phenol a methyl-ethyl-ketone an aromatic compound monohydroxyacetophenone logp 1.62 ALOGPS logs -1.43 ALOGPS solubility 5.02e+00 g/l ALOGPS melting_point Mp 109° logp 1.23 ChemAxon pka_strongest_acidic 7.79 ChemAxon pka_strongest_basic -6.9 ChemAxon iupac 1-(4-hydroxyphenyl)ethan-1-one ChemAxon average_mass 136.1479 ChemAxon mono_mass 136.0524295 ChemAxon smiles CC(=O)C1=CC=C(O)C=C1 ChemAxon formula C8H8O2 ChemAxon inchi InChI=1S/C8H8O2/c1-6(9)7-2-4-8(10)5-3-7/h2-5,10H,1H3 ChemAxon inchikey TXFPEBPIARQUIG-UHFFFAOYSA-N ChemAxon polar_surface_area 37.3 ChemAxon refractivity 38.44 ChemAxon polarizability 14.03 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 109545 Specdb::MsMs 109546 Specdb::MsMs 109547 Specdb::MsMs 177000 Specdb::MsMs 177001 Specdb::MsMs 177002 Specdb::MsMs 1476101 Specdb::MsMs 1476102 Specdb::CMs 94182 28032 Sweet orange Type 1 specific Citrus sinensis 2711 balsam hawthorn mild mimosa sweet