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Showing Compound 3-(4-Methoxyphenyl)-2-propenal (FDB010552)

Record Information
Version1.0
Creation date2010-04-08 22:09:11 UTC
Update date2019-11-26 03:03:46 UTC
Primary IDFDB010552
Secondary Accession NumbersNot Available
Chemical Information
FooDB Name3-(4-Methoxyphenyl)-2-propenal
Description3-(4-Methoxyphenyl)-2-propenal, also known as 4-methoxycinnamaldehyde, belongs to the class of organic compounds known as cinnamaldehydes. These are organic aromatic compounds containing a cinnamlaldehyde moiety, consisting of a benzene and an aldehyde group to form 3-phenylprop-2-enal. 3-(4-Methoxyphenyl)-2-propenal is a sweet, cherry, and cinnamon tasting compound. 3-(4-Methoxyphenyl)-2-propenal is found, on average, in the highest concentration within tarragons (Artemisia dracunculus). 3-(4-Methoxyphenyl)-2-propenal has also been detected, but not quantified in, a few different foods, such as potatos (Solanum tuberosum), star anises (Illicium verum), and sweet basils (Ocimum basilicum). This could make 3-(4-methoxyphenyl)-2-propenal a potential biomarker for the consumption of these foods. Based on a literature review very few articles have been published on 3-(4-Methoxyphenyl)-2-propenal.
CAS Number24680-50-0
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
SynonymSource
4-MethoxycinnamaldehydeKegg
(2E)-3-(4-Methoxyphenyl)-2-propenalHMDB
(2E)-3-(4-Methoxyphenyl)acrylaldehydeHMDB
3-(4-Methoxyphenyl)-(2E)-2-propenalHMDB
3-(4-Methoxyphenyl)acrylaldehydeHMDB
Cinnamaldehyde, P-methoxy- (8ci)HMDB
P-Methoxy cinnamaldehydeHMDB
P-Methoxy-cinnamaldehydeHMDB
P-MethoxycinnamaldehydeHMDB
P-Methoxycinnamic aldehydeHMDB
Para-methoxy cinnamic aldehydeHMDB
trans-4-MethoxycinnamaldehydeHMDB
trans-P-MethoxycinnamaldehydeHMDB
4-Methoxy-cinnamaldehydeMeSH
(2E)-3-(4-methoxyphenyl)-2-propenalbiospider
(2E)-3-(4-methoxyphenyl)acrylaldehydebiospider
2-Propenal, 3-(4-methoxyphenyl)-biospider
2-propenal, 3-(4-methoxyphenyl)-, (2E)-biospider
3-(4-Methoxyphenyl)-(2e)-2-propenalHMDB
3-(4-Methoxyphenyl)-2-propenaldb_source
3-(4-methoxyphenyl)acrylaldehydebiospider
4-methoxycinnamaldehydebiospider
Cinnamaldehyde, p-methoxy-biospider
Cinnamaldehyde, p-methoxy- (8CI)biospider
FEMA 3567db_source
ghl.PD_Mitscher_leg0.403biospider
Methoxycinnamaldehyde, p-biospider
P-methoxy cinnamaldehydebiospider
p-Methoxycinnamaldehydedb_source
P-methoxycinnamic aldehydebiospider
Trans-p-methoxycinnamaldehydebiospider
Predicted Properties
PropertyValueSource
Water Solubility0.28 g/LALOGPS
logP2.06ALOGPS
logP1.82ChemAxon
logS-2.8ALOGPS
pKa (Strongest Basic)-4.2ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area26.3 ŲChemAxon
Rotatable Bond Count3ChemAxon
Refractivity48.6 m³·mol⁻¹ChemAxon
Polarizability17.54 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Chemical FormulaC10H10O2
IUPAC name(2E)-3-(4-methoxyphenyl)prop-2-enal
InChI IdentifierInChI=1S/C10H10O2/c1-12-10-6-4-9(5-7-10)3-2-8-11/h2-8H,1H3/b3-2+
InChI KeyAXCXHFKZHDEKTP-NSCUHMNNSA-N
Isomeric SMILESCOC1=CC=C(\C=C\C=O)C=C1
Average Molecular Weight162.1852
Monoisotopic Molecular Weight162.068079564
Classification
Description Belongs to the class of organic compounds known as cinnamaldehydes. These are organic aromatic compounds containing a cinnamlaldehyde moiety, consisting of a benzene and an aldehyde group to form 3-phenylprop-2-enal.
KingdomOrganic compounds
Super ClassPhenylpropanoids and polyketides
ClassCinnamaldehydes
Sub ClassNot Available
Direct ParentCinnamaldehydes
Alternative Parents
Substituents
  • Cinnamaldehyde
  • Phenoxy compound
  • Anisole
  • Methoxybenzene
  • Styrene
  • Phenol ether
  • Alkyl aryl ether
  • Benzenoid
  • Monocyclic benzene moiety
  • Alpha,beta-unsaturated aldehyde
  • Enal
  • Ether
  • Carbonyl group
  • Organooxygen compound
  • Hydrocarbon derivative
  • Organic oxide
  • Organic oxygen compound
  • Aldehyde
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors
Ontology
Disposition

Route of exposure:

Source:

Biological location:

Role

Industrial application:

Physico-Chemical Properties
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateNot Available
Physical DescriptionNot Available
Mass CompositionC 74.06%; H 6.21%; O 19.73%DFC
Melting PointMp 58-59°DFC
Boiling PointBp15 171°DFC
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
EI-MS/GC-MS
TypeDescriptionSplash KeyView
EI-MSMass Spectrum (Electron Ionization)splash10-03e9-3900000000-dc04801eb543a1f07abf2015-03-01View Spectrum
Predicted GC-MS3-(4-Methoxyphenyl)-2-propenal, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positivesplash10-01q9-1900000000-4f28e127b93f78c5ce10Spectrum
Predicted GC-MS3-(4-Methoxyphenyl)-2-propenal, non-derivatized, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MS3-(4-Methoxyphenyl)-2-propenal, non-derivatized, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
MS/MS
TypeDescriptionSplash KeyView
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-0900000000-cb9f289edd85f0b217f82016-06-03View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03di-1900000000-03ed6a2560274a83ef9f2016-06-03View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0kai-6900000000-fbb7329572f355c4e9c22016-06-03View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-03di-0900000000-1d977d90eaae07efb2e12016-08-03View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-03di-0900000000-d21cc57534719dff36a82016-08-03View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0002-2900000000-832be9ce36fc5d88e52f2016-08-03View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03k9-0900000000-78e9accbb5efe4eae0692021-09-22View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-01vk-2900000000-91d147a66a74028f4fc02021-09-22View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-004i-9400000000-41977852e0343c9028012021-09-22View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-03di-0900000000-b7d6ddd793a969175f512021-09-22View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0gc0-1900000000-106205308fd790cd26722021-09-22View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-014i-1900000000-81dae6b2bfa2fc3b33042021-09-22View Spectrum
NMR
TypeDescriptionView
ChemSpider ID556586
ChEMBL IDCHEMBL452173
KEGG Compound IDC10475
Pubchem Compound ID641294
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB32611
CRC / DFC (Dictionary of Food Compounds) IDFBV33-U:FCV84-R
EAFUS ID2208
Dr. Duke IDP-METHOXYCINNAMALDEHYDE
BIGG IDNot Available
KNApSAcK IDC00002757
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDrw1031801
SuperScent IDNot Available
Wikipedia IDNot Available
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / Bioactivities
DescriptorIDDefinitionReference
Herbicide24527 A chemical agent that kills or inhibits plant growth, used in agriculture to control weeds and pests. It has no direct biological role or therapeutic applications in human medicine, but its development has led to the creation of related compounds with potential medical uses, such as anticancer agents.DUKE
Pesticide25944 An agent that kills or repels pests, playing a biological role in controlling insect, weed, and fungal populations. Therapeutically, pesticides have limited applications, but some are used to treat ectoparasitic infestations, such as lice and scabies. Key medical uses include topical treatments for head lice and scabies, highlighting their role in managing parasitic infections.DUKE
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
Flavours
FlavorCitations
spicy
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
floral
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
sweet
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
cinnamon
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
cherry
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
vanilla
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
Files
MSDSNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference— Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004).
— Shinbo, Y., et al. 'KNApSAcK: a comprehensive species-metabolite relationship database.' Plant Metabolomics. Springer Berlin Heidelberg, 2006. 165-181.