1.0 2010-04-08 22:09:20 UTC 2025-11-18 23:22:33 UTC FDB010856 Rhein Present in Rheum palmatum (Chinese rhubarb). Rhein is found in dock, green vegetables, and garden rhubarb. 1,8-dihydroxy-3-carboxyl anthraquinone 1,8-dihydroxy-3-carboxyl-9,10-anthraquinone 1,8-Dihydroxyanthraquinone-3-carboxylic acid 2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9, 10-dioxo- 2-Anthroic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo- 4, 5-Dihydroxyanthraquinone-2-carboxylic acid 4,5-Dihydroxy-2-anthraquinonecarboxylic acid 4,5-DiOH-anthraquinone-2-COOH 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, 9CI 9,10-dihydro-4,5-Dihydroxy-9,10-dioxo-2-anthroic acid Cassic acid Chrysazin-3-carboxylic acid Dipropionyl rhein Monorhein Rhein Rhein (1,8-dihydroxy-3-carboxyl anthraquinone) Rhubarb yellow C15H8O6 284.2204 284.032087988 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid monorhein 478-43-3 OC(=O)C1=CC2=C(C(O)=C1)C(=O)C1=C(C=CC=C1O)C2=O InChI=1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21) FCDLCPWAQCPTKC-UHFFFAOYSA-N belongs to the class of organic compounds known as anthracenecarboxylic acids. These are organic compounds containing a carboxylic acid group attached to an anthracene ring system. Anthracenecarboxylic acids Organic compounds Benzenoids Anthracenes Anthracenecarboxylic acids and derivatives Aromatic homopolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Anthraquinones Aryl ketones Carboxylic acids Hydrocarbon derivatives Hydroxybenzoic acid derivatives Monocarboxylic acids and derivatives Naphthalenecarboxylic acids Organic oxides Vinylogous acids 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid 2-naphthalenecarboxylic acid 2-naphthalenecarboxylic acid or derivatives 9,10-anthraquinone Anthracene carboxylic acid Anthraquinone Aromatic homopolycyclic compound Aryl ketone Carboxylic acid Carboxylic acid derivative Hydrocarbon derivative Hydroxybenzoic acid Ketone Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Vinylogous acid Anthracenes and phenanthrenes Anthracenes and phenanthrenes Anthraquinone type anthracenes logp 2.18 ALOGPS logs -3.12 ALOGPS solubility 2.14e-01 g/l ALOGPS melting_point Mp 321° (310°) logp 3.27 ChemAxon pka_strongest_acidic 3.4 ChemAxon pka_strongest_basic -4.4 ChemAxon iupac 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid ChemAxon average_mass 284.2204 ChemAxon mono_mass 284.032087988 ChemAxon smiles OC(=O)C1=CC2=C(C(O)=C1)C(=O)C1=C(C=CC=C1O)C2=O ChemAxon formula C15H8O6 ChemAxon inchi InChI=1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21) ChemAxon inchikey FCDLCPWAQCPTKC-UHFFFAOYSA-N ChemAxon polar_surface_area 111.9 ChemAxon refractivity 72.37 ChemAxon polarizability 26.62 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 6 ChemAxon donor_count 3 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 12668 Specdb::CMs 43004 Specdb::CMs 168173 Specdb::MsMs 12638 Specdb::MsMs 12639 Specdb::MsMs 12640 Specdb::MsMs 19310 Specdb::MsMs 19311 Specdb::MsMs 19312 Specdb::MsMs 438399 Specdb::MsMs 438400 Specdb::MsMs 438401 Specdb::MsMs 438402 Specdb::MsMs 438403 Specdb::MsMs 439468 Specdb::MsMs 439469 Specdb::MsMs 439470 Specdb::MsMs 449526 Specdb::MsMs 452090 Specdb::MsMs 2233080 Specdb::MsMs 2235436 Specdb::MsMs 2244508 Specdb::MsMs 2245614 Specdb::MsMs 2246580 Specdb::MsMs 2247698 Specdb::MsMs 2250634 Specdb::MsMs 2251752 Specdb::MsMs 2254448 HMDB32876 RHN #<Reference:0x000055ce2f23c438> #<Reference:0x000055ce2f233db0> #<Reference:0x000055ce2f233b58> #<Reference:0x000055ce2f233950> #<Reference:0x000055ce2f233658> #<Reference:0x000055ce2f233400> Dock Type 1 specific Rumex 3618 Garden rhubarb Type 1 specific Rheum rhabarbarum 3621 Green vegetables Unknown generic Anti bacterial 145 A substance that kills or slows the growth of bacteria. Anti carcinomic 162 A substance that inhibits or prevents the proliferation of neoplasms. Anti cariogenic 165 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti cytomegalovirus 217 A substance that destroys or inhibits replication of viruses. Anti neoplastic 465 A substance that inhibits or prevents the proliferation of neoplasms. Anti septic 603 A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. Anti-plaque 531 Anti-viral 689 A substance that destroys or inhibits replication of viruses. Antitumor 672 A substance that inhibits or prevents the proliferation of neoplasms. Calcium antagonist 748 Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. Candidicide 756 Cathartic 784 Any substance that accelerates defecation. Compare with laxatives, which are substances that ease defecation (usually by softening faeces). A substance can be both a laxative and a cathartic. Cytotoxic 859 A role played by the molecular entity or part thereof which causes the development of a pathological process. Fungicide 940 A substance used to destroy fungal pests. Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Proteinase inhibitor 1264 A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). Purgative 1275 An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic.