1.0 2010-04-08 22:09:34 UTC 2018-05-28 22:27:10 UTC FDB011299 4',5-Dihydroxy-3',5',7,8-tetramethoxyflavone Isolated from Lepidium sativum (garden cress). 4',5-Dihydroxy-3',5',7,8-tetramethoxyflavone C19H18O8 374.3414 374.100167552 5-hydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-7,8-dimethoxy-4H-chromen-4-one 5-hydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-7,8-dimethoxychromen-4-one 111670-54-3 COC1=CC(=CC(OC)=C1O)C1=CC(=O)C2=C(O1)C(OC)=C(OC)C=C2O InChI=1S/C19H18O8/c1-23-13-5-9(6-14(24-2)17(13)22)12-7-10(20)16-11(21)8-15(25-3)18(26-4)19(16)27-12/h5-8,21-22H,1-4H3 RVWHDZPNRAOQDC-UHFFFAOYSA-N belongs to the class of organic compounds known as 8-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C8 atom of the flavonoid backbone. 8-O-methylated flavonoids Organic compounds Phenylpropanoids and polyketides Flavonoids O-methylated flavonoids Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 3'-O-methylated flavonoids 4'-hydroxyflavonoids 5-hydroxyflavonoids 7-O-methylated flavonoids Alkyl aryl ethers Anisoles Chromones Dimethoxybenzenes Flavones Heteroaromatic compounds Hydrocarbon derivatives Methoxyphenols Organic oxides Oxacyclic compounds Phenoxy compounds Pyranones and derivatives Vinylogous acids 1-benzopyran 1-hydroxy-2-unsubstituted benzenoid 3p-methoxyflavonoid-skeleton 4'-hydroxyflavonoid 5-hydroxyflavonoid 7-methoxyflavonoid-skeleton 8-methoxyflavonoid-skeleton Alkyl aryl ether Anisole Aromatic heteropolycyclic compound Benzenoid Benzopyran Chromone Dimethoxybenzene Ether Flavone Heteroaromatic compound Hydrocarbon derivative Hydroxyflavonoid M-dimethoxybenzene Methoxybenzene Methoxyphenol Monocyclic benzene moiety Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Phenol Phenol ether Phenoxy compound Pyran Pyranone Vinylogous acid logp 2.45 ALOGPS logs -3.88 ALOGPS solubility 4.93e-02 g/l ALOGPS melting_point Mp 208-210° logp 2.38 ChemAxon pka_strongest_acidic 8.49 ChemAxon pka_strongest_basic -4.3 ChemAxon iupac 5-hydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-7,8-dimethoxy-4H-chromen-4-one ChemAxon average_mass 374.3414 ChemAxon mono_mass 374.100167552 ChemAxon smiles COC1=CC(=CC(OC)=C1O)C1=CC(=O)C2=C(O1)C(OC)=C(OC)C=C2O ChemAxon formula C19H18O8 ChemAxon inchi InChI=1S/C19H18O8/c1-23-13-5-9(6-14(24-2)17(13)22)12-7-10(20)16-11(21)8-15(25-3)18(26-4)19(16)27-12/h5-8,21-22H,1-4H3 ChemAxon inchikey RVWHDZPNRAOQDC-UHFFFAOYSA-N ChemAxon polar_surface_area 103.68 ChemAxon refractivity 96.79 ChemAxon polarizability 37.62 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 8 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 23308 Specdb::CMs 43191 Specdb::CMs 158922 Specdb::MsMs 82293 Specdb::MsMs 82294 Specdb::MsMs 82295 Specdb::MsMs 143613 Specdb::MsMs 143614 Specdb::MsMs 143615 Specdb::MsMs 2306958 Specdb::MsMs 2306959 Specdb::MsMs 2306960 Specdb::MsMs 3062333 Specdb::MsMs 3062334 HMDB33276 #<Reference:0x000055ce2f542ee8>