1.0 2010-04-08 22:09:40 UTC 2025-11-18 23:28:09 UTC FDB011479 (±)-alpha-Narcotine Formed in opium, prob. as an artifact (.+-.)-&alpha;-narcotine (.+-.)-alpha-narcotine (.+-.)-narcotine (+/-) a-narcotine (±) a-Narcotine &alpha;-gnoscopine a-Gnoscopine alpha-Gnoscopine DL-narcotine Gnoscopine Narcotine, (.+-.)- C22H23NO7 413.4205 413.147452095 6,7-dimethoxy-3-{4-methoxy-6-methyl-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl}-1,3-dihydro-2-benzofuran-1-one noscapine 6035-40-1 COC1=C(OC)C2=C(C=C1)C(OC2=O)C1N(C)CCC2=CC3=C(OCO3)C(OC)=C12 InChI=1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3 AKNNEGZIBPJZJG-UHFFFAOYSA-N belongs to the class of organic compounds known as phthalide isoquinolines. These are organic compounds with a structure characterized by an isoquinoline moiety linked to phthalide. Phthalide isoquinolines Organic compounds Alkaloids and derivatives Phthalide isoquinolines Aromatic heteropolycyclic compounds Acetals Alkyl aryl ethers Amino acids and derivatives Anisoles Aralkylamines Azacyclic compounds Benzodioxoles Benzofuranones Carboxylic acid esters Hydrocarbon derivatives Lactones Monocarboxylic acids and derivatives Organic oxides Organopnictogen compounds Oxacyclic compounds Phthalides Tetrahydroisoquinolines Trialkylamines Acetal Alkyl aryl ether Amine Amino acid or derivatives Anisole Aralkylamine Aromatic heteropolycyclic compound Azacycle Benzenoid Benzodioxole Benzofuranone Carboxylic acid derivative Carboxylic acid ester Ether Hydrocarbon derivative Isobenzofuranone Isocoumaran Lactone Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Phthalide Phthalide isoquinoline Tertiary aliphatic amine Tertiary amine Tetrahydroisoquinoline logp 2.00 ALOGPS logs -3.36 ALOGPS solubility 1.81e-01 g/l ALOGPS melting_point Mp 230-233° (227-230°) logp 2.58 ChemAxon pka_strongest_acidic 14.59 ChemAxon pka_strongest_basic 6.44 ChemAxon iupac 6,7-dimethoxy-3-{4-methoxy-6-methyl-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl}-1,3-dihydro-2-benzofuran-1-one ChemAxon average_mass 413.4205 ChemAxon mono_mass 413.147452095 ChemAxon smiles COC1=C(OC)C2=C(C=C1)C(OC2=O)C1N(C)CCC2=CC3=C(OCO3)C(OC)=C12 ChemAxon formula C22H23NO7 ChemAxon inchi InChI=1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3 ChemAxon inchikey AKNNEGZIBPJZJG-UHFFFAOYSA-N ChemAxon polar_surface_area 75.69 ChemAxon refractivity 107.08 ChemAxon polarizability 42.34 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 7 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 26248 Specdb::CMs 171515 Specdb::MsMs 58020 Specdb::MsMs 58021 Specdb::MsMs 58022 Specdb::MsMs 113856 Specdb::MsMs 113857 Specdb::MsMs 113858 Specdb::MsMs 443519 Specdb::MsMs 443520 Specdb::MsMs 443521 Specdb::MsMs 443522 Specdb::MsMs 443523 Specdb::MsMs 443524 Specdb::MsMs 449292 Specdb::MsMs 449293 Specdb::MsMs 449294 Specdb::MsMs 449295 Specdb::MsMs 449296 Specdb::MsMs 451232 Specdb::MsMs 452224 Specdb::MsMs 2236650 Specdb::MsMs 2236735 Specdb::MsMs 2242314 Specdb::MsMs 2242857 Specdb::MsMs 2243006 Specdb::MsMs 2243568 HMDB33441 #<Reference:0x000055ce325c14e8>