| abortifacient | 50691 | A chemical substance that interrupts pregnancy after implantation. | DUKE |
| aldose reductase inhibitor | 48550 | An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). | DUKE |
| alpha-reductase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| anti aggregant | | | DUKE |
| anti angiogenic | 48422 | An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. | DUKE |
| anti atherosclerotic | 38070 | A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. | DUKE |
| anti cancer | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti carcinomic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti climacteric | | | DUKE |
| anti endoccytotic | | | DUKE |
| anti estrogenic | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| anti fertility | | | DUKE |
| anti hemolytic | 50248 | Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. | DUKE |
| anti implantation | | | DUKE |
| anti inflammatory | 35472 | A substance that reduces or suppresses inflammation. | DUKE |
| anti ischemic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti leukemic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti leukotriene | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| anti lymphomic | | | DUKE |
| anti melanomic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti microbial | 33281 | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. | DUKE |
| anti mitogenic | | | DUKE |
| anti mutagenic | | | DUKE |
| anti neuroblastomic | | | DUKE |
| anti osteoporotic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| antioxidant | 22586 | A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. | DUKE |
| anti proliferative | | | DUKE |
| anti prostat adenomic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti prostatitic | | | DUKE |
| anti spasmodic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| antitumor | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti ulcer | 49201 | One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. | DUKE |
| anti viral | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| apoptotic | | | DUKE |
| aromatase inhibitor | 50790 | An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones. | DUKE |
| calcium antagonist | 48706 | Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. | DUKE |
| cancer preventive | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| cardioprotective | 38070 | A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. | DUKE |
| catechol O-methyltransferase inhibitor | 48406 | An EC 2.1.1.* (methyltransferase) inhibitor that interferes with the action of catechol O-methyltransferase (EC 2.1.1.6). | DUKE |
| cytotoxic | 52209 | A role played by the molecular entity or part thereof which causes the development of a pathological process. | DUKE |
| DOPA-decarboxylase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| estrogen agonist | 63951 | An agonist at the estrogen receptor. | DUKE |
| estrogenic | | | DUKE |
| flatulent | | | DUKE |
| fungicide | 24127 | A substance used to destroy fungal pests. | DUKE |
| fungistat | | | DUKE |
| histidine-kinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| hypocholesterolemic | | | DUKE |
| immunostimulant | 50847 | A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. | DUKE |
| lipase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| monoamine-oxidase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| multidrug resistance inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| NADH-ubiquinone-oxidoreductase inhibitor | 50390 | An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2. | DUKE |
| natriuretic | | | DUKE |
| ornithine-decarboxylase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| peroxidase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| pesticide | 25944 | Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. | DUKE |
| phytoalexin | 26115 | A toxin made by a plant that acts against an organism attacking it. | DUKE |
| pituitary sensitizer | | | DUKE |
| protein-tyrosine-kinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| quinone-reductase inducer | | | DUKE |
| topoisomerase-II inhibitor | 50750 | A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (topoisomerase II), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. | DUKE |
| topoisomerase-I inhibitor | 50276 | A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. | DUKE |
| topoisomerase-II poison | 50750 | A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (topoisomerase II), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. | DUKE |
| trypanosomastat | | | DUKE |
| tyrosine-kinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| utero trophic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| VEGF inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
