1.0 2010-04-08 22:09:59 UTC 2025-11-18 23:33:46 UTC FDB012098 Solanidine Alkaloid from potato (Solanum tuberosum). Glycosides, (especies Solanines and chaconine) are trace toxic constits. of potato tubers (especies greened tubers), and interbreeding of potatoes with wild strains may increase their concn. or introduce other more toxic, solanidine glycosides Solanidine is a steroidal alkaloid, and its glycosides have been reported to have caused poisoning in man and animals. Solanidine is present in sera of healthy individuals and in amounts dependent on their dietary potato consumption. (PMID: 4007882). Solanidine is found in many foods, some of which are eggplant, yellow bell pepper, alcoholic beverages, and potato. (3b)-Solanid-5-en-3-ol (3beta)-solanid-5-en-3-ol (3β)-solanid-5-en-3-ol 22R,25S-Solanidanine 22R,25S-Solanidine 3-&beta;-Solanid-5-en-3-ol 3-b-Solanid-5-en-3-ol(9cl) 3-beta-Solanid-5-en-3-ol 3-beta-Solanid-5-en-3-ol(9cl) Solanid-5-en-3-beta-ol Solanid-5-en-3-ol Solanid-5-en-3-ol (acd/name 4.0) Solanid-5-en-3-ol, (3-beta)- Solanid-5-en-3-ol, (3-beta)- (9CI) Solanid-5-en-3-ol, (3&beta;)- Solanid-5-en-3-ol, (3beta)- Solanid-5-en-3-ol, (3beta)- (9CI) Solanid-5-en-3.beta.-ol Solanid-5-en-3&beta;-ol Solanid-5-en-3b-ol Solanid-5-en-3b-ol, 9CI solanid-5-en-3beta-ol Solanid-5-en-3beta-ol (8CI) Solanid-5-en-3beta-ol(8CI) Solanid-5-en-3β-ol Solanidin Solanidine T Solatubin Solatubine C27H43NO 397.6364 397.334465003 10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.0^{2,11}.0^{5,10}.0^{15,23}.0^{17,22}]tetracos-4-en-7-ol 10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.0^{2,11}.0^{5,10}.0^{15,23}.0^{17,22}]tetracos-4-en-7-ol 80-78-4 CC1C2CCC(C)CN2C2CC3C4CC=C5CC(O)CCC5(C)C4CCC3(C)C12 InChI=1S/C27H43NO/c1-16-5-8-23-17(2)25-24(28(23)15-16)14-22-20-7-6-18-13-19(29)9-11-26(18,3)21(20)10-12-27(22,25)4/h6,16-17,19-25,29H,5,7-15H2,1-4H3 JVKYZPBMZPJNAJ-UHFFFAOYSA-N belongs to the class of organic compounds known as solanidines and derivatives. These are steroids with a structure based on the solanidane skeleton. Solanidane arises from the conversion of a cholestane side-chain into a bicyclic system. Solanidines and derivatives Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Steroidal alkaloids Aliphatic heteropolycyclic compounds 3-hydroxy delta-5-steroids Alkaloids and derivatives Azacyclic compounds Azasteroids and derivatives Cyclic alcohols and derivatives Delta-5-steroids Hydrocarbon derivatives Indolizidines N-alkylpyrrolidines Organopnictogen compounds Piperidines Secondary alcohols Trialkylamines 3-hydroxy-delta-5-steroid 3-hydroxysteroid Alcohol Aliphatic heteropolycyclic compound Alkaloid or derivatives Amine Azacycle Azasteroid Cyclic alcohol Delta-5-steroid Hydrocarbon derivative Hydroxysteroid Indolizidine N-alkylpyrrolidine Organic nitrogen compound Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Piperidine Pyrrolidine Secondary alcohol Solanidane skeleton Tertiary aliphatic amine Tertiary amine Solid logp 4.93 ALOGPS logs -6.00 ALOGPS solubility 3.96e-04 g/l ALOGPS melting_point Mp 219° logp 4.88 ChemAxon pka_strongest_acidic 18.2 ChemAxon pka_strongest_basic 12.47 ChemAxon iupac 10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.0^{2,11}.0^{5,10}.0^{15,23}.0^{17,22}]tetracos-4-en-7-ol ChemAxon average_mass 397.6364 ChemAxon mono_mass 397.334465003 ChemAxon smiles CC1C2CCC(C)CN2C2CC3C4CC=C5CC(O)CCC5(C)C4CCC3(C)C12 ChemAxon formula C27H43NO ChemAxon inchi InChI=1S/C27H43NO/c1-16-5-8-23-17(2)25-24(28(23)15-16)14-22-20-7-6-18-13-19(29)9-11-26(18,3)21(20)10-12-27(22,25)4/h6,16-17,19-25,29H,5,7-15H2,1-4H3 ChemAxon inchikey JVKYZPBMZPJNAJ-UHFFFAOYSA-N ChemAxon polar_surface_area 23.47 ChemAxon refractivity 120.86 ChemAxon polarizability 50.45 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 87845 Specdb::MsMs 48624 Specdb::MsMs 48625 Specdb::MsMs 48626 Specdb::MsMs 115953 Specdb::MsMs 115954 Specdb::MsMs 115955 HMDB03236 28374 #<Reference:0x000055ce306c3640> #<Reference:0x000055ce306c33e8> Alcoholic beverages Unknown generic Eggplant Type 1 specific Solanum melongena 4111 Garden tomato (var.) Type 1 specific Solanum lycopersicum var. lycopersicum 397755 Green bell pepper Type 1 specific Capsicum annuum 4072 50.0 50.0 50.0 mg/100 g Orange bell pepper Type 1 specific Capsicum annuum 4072 50.0 50.0 50.0 mg/100 g Pepper Type 1 specific Capsicum annuum 4072 50.0 50.0 50.0 mg/100 g Pepper (C. frutescens) Type 1 specific Capsicum annuum var. annuum 40321 Potato Type 1 specific Solanum tuberosum 4113 825.0 1000.0 650.0 mg/100 g Red bell pepper Type 1 specific Capsicum annuum 4072 50.0 50.0 50.0 mg/100 g Yellow bell pepper Type 1 specific Capsicum annuum 4072 50.0 50.0 50.0 mg/100 g Analgesic 56 An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. Anti cholinesterase 184 An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8). Anti epileptic 265 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti feedant 275 Anti neuralgic 469 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti pruritic 558 A drug used to treat or prevent skin disorders or for the routine care of skin. Anti-asthmatic 134 A drug used to treat asthma. Anti-bronchitic 154 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-giardial 296 Anti-Parkinsonian 509 A drug used in the treatment of Parkinson's disease. Antitumor 672 A substance that inhibits or prevents the proliferation of neoplasms. Calcium antagonist 748 Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. Cardiodepressant 766 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Cardiotonic 771 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Cytotoxic 859 A role played by the molecular entity or part thereof which causes the development of a pathological process. Fungicide 940 A substance used to destroy fungal pests. Hemolytic 973 Hemorrhagic 975 Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. Memranolytic 1099 Myostimulant 1135 Narcotic 1139 A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Sedative 1311 A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. Spasmogenic 1320 Tachycardic 1345 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Teratogenic 1347 A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. Toxic 1371 A role played by the molecular entity or part thereof which causes the development of a pathological process. Vertigenic 1424