1.0 2010-04-08 22:10:07 UTC 2019-11-26 03:06:35 UTC FDB012327 Orotic acid Occurs in milk and other biol. systems. Salts used as dietary and mineral supplements Orotic acid is a heterocyclic compound and an acid; it is also known as pyrimidinecarboxylic acid. It was once believed to be part of the vitamin B complex and was called vitamin B13, but it is now known that it is not a vitamin but is instead manufactured in the body by intestinal flora. Orotic acid is found in milk and milk products. 1,2,3,4-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidecarboxylic acid 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid, 9CI 1,2,3,6-Tetrahydro-2,6-dioxopyrimidin-4-carbonsaeure 2,6-Dihydroxy-4-pyrimidinecarboxylic acid 2,6-Dihydroxypyrimidine-4-carboxylic acid 2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid 2,6-Dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid 2,6-dioxo-3H-pyrimidine-4-carboxylic acid 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo- 4-Pyrimidinecarboxylic acid, 2,6-dihydroxy- 6-Carboxy-2,4-dihydroxypyrimidine 6-Carboxyuracil 6-Uracilcarboxylic acid Acide orotique Acido orotico Acidum oroticum Animal galactose factor Lactinium Molkensaeure ORO Orodin Oropur Orotate Orotic acid, BAN, INN Orotonin Orotonsan Orotsaeure Orotsaure Oroturic Orotyl Pyrimidinecarboxylic acid Uracil-6-carbosaeure Uracil-6-carboxylate Uracil-6-carboxylic acid Vitamin B13 Whey factor C10H8N4O8 312.1925 312.034213252 bis(2,6-dihydroxypyrimidine-4-carboxylic acid) bis(vitamin B13) 65-86-1 OC(=O)C1=CC(=O)NC(=O)N1.OC(=O)C1=NC(O)=NC(O)=C1 InChI=1S/2C5H4N2O4/c2*8-3-1-2(4(9)10)6-5(11)7-3/h2*1H,(H,9,10)(H2,6,7,8,11) HTXAWQWIIRILGC-UHFFFAOYSA-N belongs to the class of organic compounds known as pyrimidinecarboxylic acids. These are pyrimidines with a structure containing a carboxyl group attached to the pyrimidine ring. Pyrimidinecarboxylic acids Organic compounds Organoheterocyclic compounds Diazines Pyrimidines and pyrimidine derivatives Azacyclic compounds Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidine carboxylic acids and derivatives Lactams Monocarboxylic acids and derivatives Organic oxides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Pyrimidones Ureas Vinylogous amides Aromatic heteromonocyclic compound Azacycle Carboxylic acid Carboxylic acid derivative Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Hydropyrimidine carboxylic acid derivative Lactam Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Pyrimidine-6-carboxylic acid Pyrimidone Urea Vinylogous amide Solid logp 0.52 ALOGPS logs -1.09 ALOGPS solubility 1.28e+01 g/l ALOGPS melting_point Mp 345-346° logp 0.76 ChemAxon pka_strongest_acidic 0.34 ChemAxon pka_strongest_basic 3.7 ChemAxon iupac bis(2,6-dihydroxypyrimidine-4-carboxylic acid) ChemAxon average_mass 312.1925 ChemAxon mono_mass 312.034213252 ChemAxon smiles OC(=O)C1=CC(=O)NC(=O)N1.OC(=O)C1=NC(O)=NC(O)=C1 ChemAxon formula C10H8N4O8 ChemAxon inchi InChI=1S/2C5H4N2O4/c2*8-3-1-2(4(9)10)6-5(11)7-3/h2*1H,(H,9,10)(H2,6,7,8,11) ChemAxon inchikey HTXAWQWIIRILGC-UHFFFAOYSA-N ChemAxon polar_surface_area 103.54 ChemAxon refractivity 33.83 ChemAxon polarizability 12.7 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 6 ChemAxon donor_count 3 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Pyrimidine Metabolism SMP00046 map00240 HMDB00226 ORO #<Reference:0x000055ce3340f130> #<Reference:0x000055ce3340ef28> #<Reference:0x000055ce3340ed70> #<Reference:0x000055ce3340eb68> #<Reference:0x000055ce3340e960> #<Reference:0x000055ce3340e7a8> #<Reference:0x000055ce3340e5c8> #<Reference:0x000055ce3340e398> #<Reference:0x000055ce3340e1b8> #<Reference:0x000055ce3340e000> #<Reference:0x000055ce3340de20> #<Reference:0x000055ce3340dc18> #<Reference:0x000055ce3340d9e8> #<Reference:0x000055ce3340d7e0> #<Reference:0x000055ce3340d628> #<Reference:0x000055ce3340d448> Milk (Cow) Type 2 specific 518.38544 950.0 53.172 uM Milk and milk products Unknown generic Uridine 5'-monophosphate synthase P11172 UMPS