| Androgenic | | An agent that stimulates male characteristic development and maintenance by binding to androgen receptors, used therapeutically to treat conditions like hypogonadism, androgen deficiency, and certain types of anemia, as well as for hormone replacement therapy and fertility treatment. | DUKE |
| Angiogenic | 50927 | A substance that promotes the formation of new blood vessels, playing a crucial role in wound healing, tissue repair, and cancer growth. Therapeutically, angiogenic agents are used to treat conditions like ischemic heart disease and stroke, while inhibitors are used to combat cancer by restricting tumor blood supply. | DUKE |
| Anorexic | 50780 | An agent that suppresses appetite, reducing food intake. Its biological role involves regulating hunger and satiety signals. Therapeutically, anorexics are used to treat obesity and weight-related disorders, promoting weight loss and improving metabolic health. Key medical uses include managing exogenous obesity and related conditions, such as diabetes and hypertension. | DUKE |
| Anti adenomic | 35610 | An agent that inhibits adenoma growth, reducing tumor formation. It plays a biological role in regulating cell proliferation and differentiation. Therapeutically, it is used to prevent or treat adenoma-related disorders, with key medical applications in managing conditions such as colon polyps, pituitary adenomas, and other glandular tumors. | DUKE |
| Anti-androgenic | 35497 | An agent that blocks the activity of male sex hormones (androgens), reducing their effects on the body. Therapeutically, it's used to treat conditions like prostate cancer, acne, and hirsutism, as well as manage symptoms of androgen-sensitive disorders, such as benign prostatic hyperplasia. | DUKE |
| Anti bacterial | 33282 | An agent that inhibits the growth of or destroys bacteria, playing a crucial role in preventing and treating infections. Therapeutically, it is used to combat bacterial infections, with key medical applications including treating pneumonia, tuberculosis, and skin infections, as well as preventing surgical site infections and sepsis. | DUKE |
| Anti-cancer | 35610 | An agent that inhibits the growth and proliferation of cancer cells, used to treat and manage various types of cancer, including chemotherapy, targeted therapy, and immunotherapy, to reduce tumor size, prevent metastasis, and improve patient survival. | DUKE |
| Anti-edemic | | An agent that relieves or prevents edema, reducing abnormal fluid accumulation in tissues or the circulatory system, commonly used to treat conditions such as swelling, inflammation, and water retention. | DUKE |
| Anti estrogenic | 35222 | An agent that blocks or reduces estrogen's effects, used to treat hormone-sensitive cancers, such as breast cancer, and manage conditions like endometriosis and uterine fibroids, by inhibiting estrogen's biological role in promoting cell growth. | DUKE |
| Anti feedant | | A substance that inhibits normal feeding behavior, found in certain plants, deterring insects and animals from consuming them. Its therapeutic applications include pest control, while key medical uses involve managing insect-borne diseases and reducing crop damage. | DUKE |
| Anti-fertility | | An agent that inhibits reproduction, playing a biological role in population control. Therapeutically, it's used as a contraceptive, with key medical applications in family planning and birth control, preventing unwanted pregnancies and managing reproductive health. | DUKE |
| Anti gonadotrophic | | An agent that inhibits gonadotropin production or activity, regulating reproductive hormone secretion. It has therapeutic applications in managing conditions like precocious puberty, hormone-sensitive cancers, and infertility, with key medical uses including contraception and treatment of endometriosis. | DUKE |
| Anti hyperlipoproteinaemic | 52217 | An agent that reduces elevated levels of lipoproteins in the blood, playing a crucial role in managing hyperlipidemia. Therapeutically, it helps lower cholesterol and triglyceride levels, reducing the risk of cardiovascular disease. Key medical uses include treating hypercholesterolemia, hypertriglyceridemia, and preventing atherosclerosis. | DUKE |
| Anti-inflammatory | 35472 | An agent that reduces inflammation, playing a biological role in suppressing immune responses and therapeutic applications in managing pain, swelling, and redness. Key medical uses include treating arthritis, allergies, and autoimmune disorders, as well as relieving symptoms of conditions such as asthma and dermatitis. | DUKE |
| Anti leukemic | 35610 | An agent that targets and inhibits the growth of leukemia cells, playing a crucial role in cancer treatment. Therapeutically, it is used to induce remission, manage symptoms, and improve survival rates in patients with leukemia. Key medical uses include treating acute and chronic leukemia, lymphoma, and other hematological malignancies. | DUKE |
| Anti-lymphomic | | An agent that targets and destroys lymphatic cells that form tumors, playing a crucial role in cancer treatment. Therapeutically, it is used to manage lymphomas, with key medical applications in chemotherapy and immunotherapy to combat blood cell cancers. | DUKE |
| Anti-mutagenic | | An agent that interferes with the mutagenicity of a substance, preventing DNA damage and mutations. Its biological role is to protect cells from genetic alterations, and it has therapeutic applications in cancer prevention and treatment, as well as key medical uses in reducing the risk of genetic disorders and birth defects. | DUKE |
| Anti ophidic | | An antivenom agent used to treat venomous bites or stings, created by milking and diluting venom from relevant species, and injected to neutralize toxins, reducing inflammation and preventing systemic complications. | DUKE |
| Anti-oxidant | 22586 | An agent that neutralizes free radicals, reducing oxidative stress and cell damage. Its biological role involves protecting cells from harm, and it has therapeutic applications in managing chronic diseases, such as cancer, diabetes, and neurodegenerative disorders, with key medical uses including anti-aging, anti-inflammatory, and cardio protective effects. | DUKE |
| Anti progestational | | An agent that blocks progesterone's effects, preventing implantation of a fertilized egg. Therapeutically, it's used for emergency contraception, abortion, and treating conditions like endometriosis and uterine fibroids, by inhibiting progesterone's role in the menstrual cycle. | DUKE |
| Anti prostaglandin | 49020 | An agent that inhibits prostaglandin production, reducing inflammation and pain. Therapeutically, it's used to treat conditions like arthritis, menstrual cramps, and post-surgical pain, by blocking prostaglandin-mediated responses, providing relief from inflammation and discomfort. | DUKE |
| Anti prostat adenomic | 35610 | An agent that inhibits the growth of prostatic adenoma cells, reducing benign prostatic hyperplasia (BPH) symptoms. It helps alleviate urinary obstruction, improving quality of life for patients with enlarged prostates, and is used to treat BPH and prevent related complications. | DUKE |
| Anti-prostatitic | | An agent that relieves prostatitis, reducing inflammation of the prostate gland, and is used to treat benign prostatic hyperplasia (BPH) and chronic pelvic pain syndrome. | DUKE |
| Anti pyretic | 35493 | An agent that reduces fever, commonly used to relieve headache, pain, and discomfort associated with elevated body temperature, and to manage fever in various medical conditions, such as infections and inflammatory diseases. | DUKE |
| Antitumor | 35610 | An agent that inhibits tumor growth and proliferation, playing a crucial role in cancer treatment. Therapeutically, antitumors are used to manage various types of cancer, including chemotherapy, targeted therapy, and immunotherapy, helping to reduce tumor size, prevent metastasis, and improve patient outcomes. | DUKE |
| Anti-viral | 22587 | An agent that inhibits the replication of viruses, playing a crucial role in preventing and treating viral infections. Therapeutically, anti-virals are used to manage diseases such as HIV, herpes, and influenza, reducing symptoms and slowing disease progression. Key medical uses include treating viral hepatitis, respiratory syncytial virus, and COVID-19. | DUKE |
| Apoptotic | | An agent that stimulates programmed cell death, playing a crucial biological role in eliminating damaged or unwanted cells. It has therapeutic applications in cancer treatment, and key medical uses include inducing cell death in malignant cells, reducing tumor growth, and enhancing chemotherapy efficacy. | DUKE |
| Artemicide | | An herbicidal agent that targets and eliminates weeds of the Artemisia genus, with potential therapeutic applications in allergy management and anti-inflammatory uses, particularly for conditions exacerbated by Artemisia allergens. | DUKE |
| Cancer preventive | 35610 | An agent that inhibits the development and progression of cancer, reducing tumor formation and growth. It plays a biological role in blocking carcinogenic pathways, and has therapeutic applications in chemoprevention. Key medical uses include reducing the risk of cancer in high-risk individuals and preventing cancer recurrence. | DUKE |
| Candidicide | | An agent that kills Candida species, such as Candida albicans, reducing fungal infections. Therapeutically, it is used to treat candidiasis, with key medical applications in managing oral thrush, vaginal yeast infections, and other fungal diseases. | DUKE |
| Caspase-8 inducer | | An apoptosis-inducing agent that stimulates caspase-8 activity, promoting cell death. It has therapeutic applications in cancer treatment, particularly in inducing apoptosis in cancer cells, and may also be used in managing inflammatory and immune disorders. | DUKE |
| Estrogenic | | An agent that mimics the effects of estrogen, regulating female reproductive processes and development. Therapeutically, estrogenic agents are used in hormone replacement therapy, contraception, and treating menopausal symptoms, as well as certain cases of osteoporosis and infertility. | DUKE |
| Febrifuge | 25944 | An agent that reduces fever, commonly used to alleviate symptoms of influenza, malaria, and other infectious diseases, providing relief from high body temperature and associated discomfort. | DUKE |
| Gonadotrophic | | A hormone-stimulating agent that regulates reproductive functions, promoting gonadal growth and development. Therapeutically, it is used to treat infertility, hypogonadism, and menstrual disorders, stimulating the production of sex hormones such as estrogen and testosterone. | DUKE |
| Hepatoprotective | 62868 | An agent that protects the liver from damage, promoting liver health and function. It plays a biological role in reducing oxidative stress and inflammation, and has therapeutic applications in managing liver diseases, such as hepatitis and cirrhosis, and key medical uses in treating drug-induced liver injury and toxicities. | DUKE |
| Hypocholesterolemic | | An agent that lowers cholesterol levels in the blood, playing a crucial role in preventing cardiovascular disease. Therapeutically, it is used to manage hyperlipidemia and reduce the risk of heart disease, with key medical applications including the treatment of high cholesterol, atherosclerosis, and coronary artery disease. | DUKE |
| Hypoglycemic | 35526 | An agent that lowers blood glucose levels, playing a crucial role in glucose metabolism. Therapeutically, it is used to manage diabetes and insulin resistance, with key medical applications in treating type 1 and 2 diabetes, and preventing diabetic complications. | DUKE |
| Hypolipidemic | | An agent that lowers lipid levels, treating hyperlipidemias by reducing cholesterol and triglyceride production, with therapeutic applications in managing cardiovascular disease, atherosclerosis, and stroke, commonly used to prevent heart attacks and improve overall cardiovascular health. | DUKE |
| Pesticide | 25944 | An agent that kills or repels pests, playing a biological role in controlling insect, weed, and fungal populations. Therapeutically, pesticides have limited applications, but some are used to treat ectoparasitic infestations, such as lice and scabies. Key medical uses include topical treatments for head lice and scabies, highlighting their role in managing parasitic infections. | DUKE |
| Spermicide | | A contraceptive substance that destroys sperm, inserted vaginally prior to intercourse to prevent pregnancy, serving as a non-hormonal birth control method. | DUKE |
| Ubiquiot | | An antioxidant that protects cells from damage, playing a crucial role in energy production. Therapeutically, it has applications in managing neurodegenerative and cardiovascular diseases, with key medical uses including reducing oxidative stress and improving mitochondrial function. | DUKE |
| Ulcerogenic | | An agent that causes the production of ulcers, often used to study gastrointestinal disease mechanisms. Its biological role involves disrupting mucosal defense, leading to ulcer formation. Therapeutically, understanding ulcerogenic agents informs the development of anti-ulcer medications. Key medical uses include researching gastric ulcer pathogenesis and testing potential treatments for ulcer prevention and healing. | DUKE |
