1.0 2010-04-08 22:10:08 UTC 2019-11-26 03:06:39 UTC FDB012374 Tylosin It is used in treatment of cattle, swine and mycoplasmas in poultry Tylosin is a macrolide-class antibiotic used in veterinary medicine. It has a broad spectrum of activity against gram positive organisms and a limited range of gram negative organisms. It is found naturally as a fermentation product of Streptomyces fradiae. Corvel-Tylocine Dehydrorelomycin Elanco-M Frazidine Norco T-2 Parkenova Tylan Tylon C46H77NO17 916.1001 915.519150043 2-[(11E,13E)-6-({5-[(4,5-dihydroxy-4,6-dimethyloxan-2-yl)oxy]-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl}oxy)-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl)oxy]methyl}-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde 2-[(11E,13E)-6-({5-[(4,5-dihydroxy-4,6-dimethyloxan-2-yl)oxy]-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl}oxy)-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl)oxy]methyl}-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde 1401-69-0 CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(C2O)N(C)C)C(CC=O)CC(C)C(=O)\C=C\C(\C)=C\C1COC1OC(C)C(O)C(OC)C1OC InChI=1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+ WBPYTXDJUQJLPQ-LLMNDNAOSA-N belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars. Aminoglycosides Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Aliphatic heteromonocyclic compounds 1,2-aminoalcohols Acetals Alpha-hydrogen aldehydes Amino acids and derivatives Carboxylic acid esters Cyclic ketones Dialkyl ethers Disaccharides Hydrocarbon derivatives Lactones Macrolides and analogues Monocarboxylic acids and derivatives O-glycosyl compounds Organic oxides Organopnictogen compounds Oxacyclic compounds Oxanes Secondary alcohols Tertiary alcohols Trialkylamines 1,2-aminoalcohol Acetal Alcohol Aldehyde Aliphatic heteromonocyclic compound Alpha-hydrogen aldehyde Amine Amino acid or derivatives Aminoglycoside core Carbonyl group Carboxylic acid derivative Carboxylic acid ester Cyclic ketone Dialkyl ether Disaccharide Ether Glycosyl compound Hydrocarbon derivative Ketone Lactone Macrolide Monocarboxylic acid or derivatives O-glycosyl compound Organic nitrogen compound Organic oxide Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Oxacycle Oxane Secondary alcohol Tertiary alcohol Tertiary aliphatic amine Tertiary amine logp 1.46 ALOGPS logs -3.64 ALOGPS solubility 2.11e-01 g/l ALOGPS melting_point Mp 131° logp 2.32 ChemAxon pka_strongest_acidic 12.45 ChemAxon pka_strongest_basic 7.2 ChemAxon iupac 2-[(11E,13E)-6-({5-[(4,5-dihydroxy-4,6-dimethyloxan-2-yl)oxy]-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl}oxy)-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl)oxy]methyl}-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde ChemAxon average_mass 916.1001 ChemAxon mono_mass 915.519150043 ChemAxon smiles CCC1OC(=O)CC(O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(C2O)N(C)C)C(CC=O)CC(C)C(=O)\C=C\C(\C)=C\C1COC1OC(C)C(O)C(OC)C1OC ChemAxon formula C46H77NO17 ChemAxon inchi InChI=1S/C46H77NO17/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3/b15-14+,23-18+ ChemAxon inchikey WBPYTXDJUQJLPQ-LLMNDNAOSA-N ChemAxon polar_surface_area 238.67 ChemAxon refractivity 232.21 ChemAxon polarizability 98.82 ChemAxon rotatable_bond_count 13 ChemAxon acceptor_count 17 ChemAxon donor_count 5 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 367147 Specdb::MsMs 367148 Specdb::MsMs 367149 Specdb::MsMs 2662405 Specdb::MsMs 2662406 Specdb::MsMs 2662407 Specdb::MsMs 319897 Specdb::MsMs 319898 Specdb::MsMs 319899 Specdb::MsMs 3015603 Specdb::MsMs 3015604 Specdb::MsMs 3015605 HMDB34108 17658 #<Reference:0x00007f41bc172fc8> #<Reference:0x00007f41bc172e10> #<Reference:0x00007f41bc172c08> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Milk (Cow) Type 2 specific 0.0599 0.0599 0.0599 uM Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823