| Anti aflatoxin | 35222 | An agent that neutralizes or removes aflatoxins, toxic compounds produced by mold, reducing the risk of liver damage and cancer. Therapeutically, it is used to prevent aflatoxin poisoning, commonly in food safety and liver protection applications, and may have potential in cancer prevention and treatment. | DUKE |
| Anti-alopecic | 52217 | An agent that promotes hair growth and prevents hair loss, commonly used to treat alopecia and other hair-related disorders, by inhibiting dihydrotestosterone (DHT) and stimulating hair follicle growth. | DUKE |
| Anti bacterial | 33282 | An agent that inhibits the growth of or destroys bacteria, playing a crucial role in preventing and treating infections. Therapeutically, it is used to combat bacterial infections, with key medical applications including treating pneumonia, tuberculosis, and skin infections, as well as preventing surgical site infections and sepsis. | DUKE |
| Anti dermatitic | 50177 | An agent that reduces skin inflammation and irritation, commonly used to treat dermatitis, eczema, and other skin disorders, providing relief from itching, redness, and swelling. | DUKE |
| Anti feedant | | A substance that inhibits normal feeding behavior, found in certain plants, deterring insects and animals from consuming them. Its therapeutic applications include pest control, while key medical uses involve managing insect-borne diseases and reducing crop damage. | DUKE |
| Anti histaminic | 37956 | An agent that blocks histamine receptors, reducing allergic symptoms. Therapeutically, it alleviates itching, sneezing, and runny nose, commonly used in managing allergies, itching, and hives, as well as treating conditions like anaphylaxis and allergic rhinitis. | DUKE |
| Anti-inflammatory | 35472 | An agent that reduces inflammation, playing a biological role in suppressing immune responses and therapeutic applications in managing pain, swelling, and redness. Key medical uses include treating arthritis, allergies, and autoimmune disorders, as well as relieving symptoms of conditions such as asthma and dermatitis. | DUKE |
| Anti keratotic | | An agent that treats keratosis, reducing overgrowth of skin's horny tissue, commonly used to manage warts, calluses, and other skin thickening conditions, promoting healthy skin regeneration. | DUKE |
| Anti-leucodermic | | An agent used to treat vitiligo, promoting repigmentation by stimulating melanocyte function, and restoring skin color to areas with white patches, often caused by depigmentation. | DUKE |
| Anti-lymphomic | | An agent that targets and destroys lymphatic cells that form tumors, playing a crucial role in cancer treatment. Therapeutically, it is used to manage lymphomas, with key medical applications in chemotherapy and immunotherapy to combat blood cell cancers. | DUKE |
| Anti mitotic | | An agent that inhibits mitosis, or cell division, playing a crucial role in regulating cell growth. Therapeutically, it is used to treat cancer by blocking tumor cell proliferation. Key medical uses include chemotherapy for various cancers, such as breast, lung, and colon cancer, to prevent cancer cell division and growth. | DUKE |
| Anti-mutagenic | | An agent that interferes with the mutagenicity of a substance, preventing DNA damage and mutations. Its biological role is to protect cells from genetic alterations, and it has therapeutic applications in cancer prevention and treatment, as well as key medical uses in reducing the risk of genetic disorders and birth defects. | DUKE |
| Anti mycotic | | An agent that destroys or prevents the growth of fungi, playing a crucial role in treating fungal infections. Therapeutically, it is used to manage conditions such as athlete's foot, ringworm, and candidiasis, and has key medical applications in dermatology and immunocompromised patient care. | DUKE |
| Anti-pityriasic | | An agent that relieves symptoms of skin diseases, such as pityriasis, characterized by fine, branny scales, reducing inflammation and itching, commonly used in treating conditions like seborrheic dermatitis and psoriasis. | DUKE |
| Anti pruritic | 50177 | An agent that relieves itching sensations, reducing scratching and discomfort. It plays a biological role in inhibiting histamine release and nerve signal transmission. Therapeutically, it's used to manage itching associated with allergies, eczema, and skin irritations, providing relief and preventing further skin damage. | DUKE |
| Anti-psoriac | 52217 | An agent that reduces psoriasis symptoms, commonly used in managing plaque psoriasis, scalp psoriasis, and other inflammatory skin conditions, by inhibiting cell growth, reducing inflammation, and modulating the immune system. | DUKE |
| Anti scleromyxoedemic | 50177 | An agent that reduces scleromyxoedema, a rare skin condition characterized by mucin deposition and fibrosis. It inhibits abnormal fibroblast activity, reducing skin thickening and lesions. Therapeutically, it's used to manage scleromyxoedema, lichen sclerosus, and other fibrotic skin disorders, improving skin texture and reducing symptoms. | DUKE |
| Anti-spasmodic | 52217 | An agent that relaxes smooth muscle, reducing muscle spasms and cramps. It plays a biological role in regulating muscle tone and is therapeutically applied to treat conditions such as irritable bowel syndrome, menstrual cramps, and muscle spasms, providing relief from abdominal pain and discomfort. | DUKE |
| Anti-staphylococcic | 33282 | An agent that combats Staphylococcus infections, playing a crucial role in preventing bacterial growth. Therapeutically, it is used to treat skin and soft tissue infections, respiratory tract infections, and bloodstream infections. Key medical uses include treating methicillin-resistant Staphylococcus aureus (MRSA) and other staphylococcal infections, reducing the risk of infection and promoting wound healing. | DUKE |
| Antitumor | 35610 | An agent that inhibits tumor growth and proliferation, playing a crucial role in cancer treatment. Therapeutically, antitumors are used to manage various types of cancer, including chemotherapy, targeted therapy, and immunotherapy, helping to reduce tumor size, prevent metastasis, and improve patient outcomes. | DUKE |
| Antitumor promoter | 35610 | An agent that inhibits tumor growth and progression, reducing cancer cell proliferation. Therapeutically, it prevents tumor development and spread, with key medical uses in cancer prevention and treatment, particularly in combating carcinogenesis and metastasis. | DUKE |
| Anti-viral | 22587 | An agent that inhibits the replication of viruses, playing a crucial role in preventing and treating viral infections. Therapeutically, anti-virals are used to manage diseases such as HIV, herpes, and influenza, reducing symptoms and slowing disease progression. Key medical uses include treating viral hepatitis, respiratory syncytial virus, and COVID-19. | DUKE |
| Anti-vitiligic | | An agent that prevents loss of skin pigmentation, characteristic of vitiligo, promoting melanocyte preservation and repigmentation, used therapeutically to manage vitiligo and other hypopigmentation disorders. | DUKE |
| Artemicide | | An herbicidal agent that targets and eliminates weeds of the Artemisia genus, with potential therapeutic applications in allergy management and anti-inflammatory uses, particularly for conditions exacerbated by Artemisia allergens. | DUKE |
| Bufocide | | A cardiotonic steroid, bufocide plays a biological role in regulating cardiac function. Therapeutically, it has applications as a cardiostimulant and diuretic. Key medical uses include treating heart failure and edema, with potential in managing certain arrhythmias and hypertension. | DUKE |
| Calcium antagonist | 48706 | A medication that blocks calcium ion entry into cells, reducing muscle contraction and vascular resistance. It treats hypertension, angina, and arrhythmias by dilating blood vessels and decreasing cardiac workload, commonly used in managing cardiovascular diseases. | DUKE |
| Cancer preventive | 35610 | An agent that inhibits the development and progression of cancer, reducing tumor formation and growth. It plays a biological role in blocking carcinogenic pathways, and has therapeutic applications in chemoprevention. Key medical uses include reducing the risk of cancer in high-risk individuals and preventing cancer recurrence. | DUKE |
| Candidicide | | An agent that kills Candida species, such as Candida albicans, reducing fungal infections. Therapeutically, it is used to treat candidiasis, with key medical applications in managing oral thrush, vaginal yeast infections, and other fungal diseases. | DUKE |
| Carcinogenic | 50903 | An agent that causes cancer, damaging cellular DNA and disrupting normal cell growth. It has no therapeutic applications, but understanding its biological role informs cancer prevention and treatment strategies, with key medical uses in oncology research and risk assessment. | DUKE |
| Cytotoxic | 52209 | An agent that kills or damages cells, playing a biological role in immune responses and therapeutic applications in cancer treatment. Key medical uses include chemotherapy, targeting and destroying cancer cells, and treating certain autoimmune diseases by eliminating harmful cells. | DUKE |
| Dermatitigenic | | An agent that causes inflammation of the skin (dermatitis), triggering allergic reactions and immune responses. Its biological role involves activating immune cells, leading to skin irritation. Therapeutically, it is used to test skin sensitivity and develop treatments for dermatitis. Key medical uses include diagnosing skin allergies and researching dermatitis treatments. | DUKE |
| Emetic | | An agent that induces vomiting, playing a biological role in expelling toxins from the body. Therapeutically, it is used to treat poisoning, overdose, or gastrointestinal obstruction. Key medical uses include managing drug toxicity and aiding in stomach pumping procedures. | DUKE |
| Fungicide | 24127 | An agent that kills or inhibits the growth of fungi, playing a biological role in preventing fungal infections. Therapeutically, it is used to treat fungal diseases, with key medical applications including athlete's foot, ringworm, and candidiasis, as well as agricultural uses to protect crops from fungal damage. | DUKE |
| Fungistat | | An agent that inhibits fungal growth, used to prevent fungal infections, commonly applied in therapeutic applications such as treating skin and nail infections, and managing fungal diseases in immunocompromised patients. | DUKE |
| Hepatoprotective | 62868 | An agent that protects the liver from damage, promoting liver health and function. It plays a biological role in reducing oxidative stress and inflammation, and has therapeutic applications in managing liver diseases, such as hepatitis and cirrhosis, and key medical uses in treating drug-induced liver injury and toxicities. | DUKE |
| Herbicide | 24527 | A chemical agent that kills or inhibits plant growth, used in agriculture to control weeds and pests. It has no direct biological role or therapeutic applications in human medicine, but its development has led to the creation of related compounds with potential medical uses, such as anticancer agents. | DUKE |
| Hypertrichotic | | An agent that stimulates excessive hair growth, used therapeutically to treat conditions like alopecia and hair loss, with potential applications in dermatology and cosmetic medicine. | DUKE |
| Immunosuppressant | 35705 | An agent that suppresses the immune system, reducing inflammation and preventing rejection in organ transplants, and treating autoimmune diseases such as rheumatoid arthritis and lupus. | DUKE |
| Insecticide | 24852 | An agent that kills or repels insects, used to control pests and prevent disease transmission. Therapeutically, insecticides have applications in public health and veterinary medicine, key medical uses include controlling insect-borne diseases such as malaria, typhus, and Lyme disease. | DUKE |
| Lipolytic | | An agent that stimulates hydrolysis of fats into fatty acids and glycerol, playing a key biological role in fat metabolism. Therapeutically, lipolytics have applications in managing obesity and hypertriglyceridemia, with medical uses including weight loss and improving lipid profiles. | DUKE |
| Lymphocytogenic | | An agent that stimulates production of lymphocytes, enhancing immune response. Therapeutically, it promotes lymphocyte growth, aiding in cancer treatment and immune system disorders. Key medical uses include immunotherapy and treating lymphopenia, or low lymphocyte count, to boost the body's natural defense mechanisms. | DUKE |
| Melaninogenic | | An agent that stimulates melanin production, determining skin and hair color. It has therapeutic applications in treating hypopigmentation disorders, such as vitiligo, and key medical uses include skin pigmentation and protection against UV radiation. | DUKE |
| Mitogenic | | A substance that stimulates cell division, triggering mitosis, with roles in growth, development, and tissue repair. Therapeutically, mitogens are used to enhance wound healing, tissue regeneration, and in cancer treatments to stimulate immune response. Key medical uses include promoting cell growth in damaged tissues and supporting hematopoiesis. | DUKE |
| Molluscicide | 33904 | An agent that kills mollusks, particularly snails and slugs, playing a key role in controlling vectors of parasitic diseases. Therapeutically, it is used to prevent the spread of schistosomiasis and other snail-borne diseases, with medical applications in public health and epidemiology. | DUKE |
| Mutagenic | | An agent that induces genetic mutations, altering DNA sequences. It plays a biological role in evolution and adaptation. Therapeutically, mutagenic agents are used in cancer treatment, such as chemotherapy, and in gene therapy to introduce beneficial traits. Key medical uses include oncology and genetic research. | DUKE |
| Pesticide | 25944 | An agent that kills or repels pests, playing a biological role in controlling insect, weed, and fungal populations. Therapeutically, pesticides have limited applications, but some are used to treat ectoparasitic infestations, such as lice and scabies. Key medical uses include topical treatments for head lice and scabies, highlighting their role in managing parasitic infections. | DUKE |
| Photodermatitigenic | | An agent that, when activated by light, triggers an allergic response, causing a rash or systemic effects, used to study skin sensitivity and photosensitivity disorders, with applications in dermatology and allergy testing. | DUKE |
| Phototoxic | | An agent that causes skin damage, such as sunburn or blisters, upon exposure to light, especially ultraviolet light, with no therapeutic applications but key medical uses in diagnosing photosensitivity disorders. | DUKE |
| Phytoalexin | 26115 | A plant-derived compound that plays a biological role in defense against pathogens. It has therapeutic applications as an antimicrobial, antioxidant, and anti-inflammatory agent, with key medical uses in managing infections, cancer, and neurodegenerative diseases. | DUKE |
| Piscicide | | A substance poisonous to fish, used to eliminate dominant or invasive fish species, and combat parasitic fish, allowing for population control and management of aquatic ecosystems. | DUKE |
