1.0 2010-04-08 22:10:20 UTC 2019-11-26 03:07:32 UTC FDB012757 Thymine 2-desoxyriboside Isolated from seedlings of Phaseolus vulgaris (kidney bean) Deoxythymidine is non-toxic and as part of one of the four nucleotides in DNA it is a naturally occurring compound that exists in all living organisms and DNA viruses. RNA has uridine (uracil joined to ribose) instead. Uracil is chemically very similar to thymine, the latter being 5-methyluracil. Since thymine nucleotides are precursors of DNA, not RNA, the prefix "deoxy" is often left out, i.e., deoxythymidine is often just called thymidine.; In its composition, deoxythymidine is a nucleoside composed of deoxyribose (a pentose sugar) joined to the pyrimidine base thymine.; Iododeoxyuridine is a radiosensitizer and increases the amount of DNA damage received from ionizing radiation.; Thymidine (more precisely called deoxythymidine; can also be labelled deoxyribosylthymine, and thymine deoxyriboside) is a chemical compound, more precisely a pyrimidine deoxynucleoside. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in S phase.; Thymidine is non-toxic and is a naturally occurring compound that exists in all living organisms and DNA viruses. 25% of DNA is composed of thymidine. RNA does not have thymidine and has uridine instead. Thymidine is a chemical compound which is a pyrimidine nucleoside. Thymidine is the DNA base T, which pairs with adenosine in double stranded DNA. Thymine 2-desoxyriboside is found in pulses, yellow wax bean, and green bean. (3H)Thymidine &beta;-D-Ribofuranoside, thymine-1 2-deoxy- 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione, 9CI 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil 1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-(2-Deoxy-beta-D-ribofuranosyl)-5-methyluracil 1-(2-Deoxy-beta-D-ribofuranosyl)thymine 1-(2-Deoxy-beta-delta-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione 1-(2-Deoxy-beta-ribofuranosyl)-5-methyluracil 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione 2-deoxythymidine 2-Desoxy-thymidine 2'-deoxy-5-methyl-Uridine 2'-deoxy-5-methyluridine 2'-Deoxythymidine 2'-thymidine 5-Methyl-2'-deoxyuridine 5-Methyldeoxyuridine 5-Methyldeoxyurindine beta-D-Ribofuranoside, thymine-1 2-deoxy- Deoxyribothymidine Deoxythymidin Deoxythymidine Desoxy-thymidin DT DTHD Dthyd NSC 21548 THM Thymidin Thymidine Thymidine (8CI,9CI) Thymidine-(H-3) Thymidine, 2'-deoxy- Thymidine, labeled with tritium Thymine 2-desoxyriboside thymine 2'-deoxyriboside Thymine deoxyriboside thymine-1 2-deoxy-b-D-Ribofuranoside thymine-1 2-deoxy-beta-delta-Ribofuranoside Thymine-2-deoxyriboside Thymine-2-desoxyriboside Thyminedeoxyriboside Thymosine Tritiated thymidine Uridine, 2'-deoxy-5-methyl- C10H14N2O5 242.2286 242.090271568 4-hydroxy-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2-dihydropyrimidin-2-one 4-hydroxy-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one 50-89-5 CC1=CN(C2CC(O)C(CO)O2)C(=O)N=C1O InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16) IQFYYKKMVGJFEH-UHFFFAOYSA-N belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleosides. Pyrimidine 2'-deoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. Pyrimidine 2'-deoxyribonucleosides Organic compounds Nucleosides, nucleotides, and analogues Pyrimidine nucleosides Pyrimidine 2'-deoxyribonucleosides Aromatic heteromonocyclic compounds Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Lactams Organic oxides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Primary alcohols Pyrimidones Secondary alcohols Tetrahydrofurans Ureas Vinylogous amides Alcohol Aromatic heteromonocyclic compound Azacycle Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Lactam Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Primary alcohol Pyrimidine Pyrimidine 2'-deoxyribonucleoside Pyrimidone Secondary alcohol Tetrahydrofuran Urea Vinylogous amide a deoxynucleoside a pyrimidine-related compound Solid logp -1.66 ALOGPS logs -1.09 ALOGPS solubility 1.98e+01 g/l ALOGPS melting_point Mp 186-187° logp -0.75 ChemAxon pka_strongest_acidic 7.52 ChemAxon pka_strongest_basic -3 ChemAxon iupac 4-hydroxy-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2-dihydropyrimidin-2-one ChemAxon average_mass 242.2286 ChemAxon mono_mass 242.090271568 ChemAxon smiles CC1=CN(C2CC(O)C(CO)O2)C(=O)N=C1O ChemAxon formula C10H14N2O5 ChemAxon inchi InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16) ChemAxon inchikey IQFYYKKMVGJFEH-UHFFFAOYSA-N ChemAxon polar_surface_area 102.59 ChemAxon refractivity 55.73 ChemAxon polarizability 23.08 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 6 ChemAxon donor_count 3 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Pyrimidine Metabolism SMP00046 map00240 Specdb::EiMs 1004 Specdb::NmrOneD 2408 Specdb::NmrOneD 3098 Specdb::NmrOneD 221257 Specdb::NmrOneD 221258 Specdb::NmrOneD 221259 Specdb::NmrOneD 221260 Specdb::NmrOneD 221261 Specdb::NmrOneD 221262 Specdb::NmrOneD 221263 Specdb::NmrOneD 221264 Specdb::NmrOneD 221265 Specdb::NmrOneD 221266 Specdb::NmrOneD 221267 Specdb::NmrOneD 221268 Specdb::NmrOneD 221269 Specdb::NmrOneD 221270 Specdb::NmrOneD 221271 Specdb::NmrOneD 221272 Specdb::NmrOneD 221273 Specdb::NmrOneD 221274 Specdb::NmrOneD 221275 Specdb::NmrOneD 221276 Specdb::CMs 112542 Specdb::CMs 126052 Specdb::CMs 919929 Specdb::CMs 919930 Specdb::CMs 919931 Specdb::CMs 919932 Specdb::CMs 919933 Specdb::CMs 919934 Specdb::CMs 919935 Specdb::CMs 919936 Specdb::CMs 919937 Specdb::CMs 919938 Specdb::CMs 919939 Specdb::CMs 919940 Specdb::CMs 919941 Specdb::CMs 919942 Specdb::MsMs 21125 Specdb::MsMs 21126 Specdb::MsMs 21127 Specdb::MsMs 22676 Specdb::MsMs 22677 Specdb::MsMs 22678 Specdb::MsMs 3441508 Specdb::MsMs 3441509 Specdb::MsMs 3441510 Specdb::MsMs 3441511 Specdb::MsMs 3441512 Specdb::MsMs 3441513 HMDB00273 17748 THM #<Reference:0x000055ce30d1a0c0> #<Reference:0x000055ce30d181d0> #<Reference:0x000055ce30d0fe68> #<Reference:0x000055ce30d0fcb0> #<Reference:0x000055ce30d0faf8> #<Reference:0x000055ce30d0f940> #<Reference:0x000055ce30d0f710> #<Reference:0x000055ce30d0f490> #<Reference:0x000055ce30d0f2b0> #<Reference:0x000055ce30d0f008> #<Reference:0x000055ce30d0ee50> Beer Type 2 specific 0.0 0.0 0.0 mg/100 g Green bean Type 1 specific Phaseolus vulgaris 3885 Pulses Unknown generic Yellow wax bean Type 1 specific Phaseolus vulgaris 3885 Cytosolic 5'-nucleotidase 3 Q9H0P0 NT5C3 Thymidine kinase 2, mitochondrial O00142 TK2 Thymidine kinase, cytosolic P04183 TK1 Thymidine phosphorylase P19971 TYMP