1.0 2010-04-08 22:10:23 UTC 2019-11-26 03:07:41 UTC FDB012833 Cytidine 5'-triphosphate Found in cheese and liver CTP is a high-energy molecule equal to ATP, but its role in the organism is more specific than that of ATP. CTP is used as the source of energy, and as a coenzyme in metabolic reactions like the synthesis of glycerophospholipids and glycosylation of proteins.; CTP is a substrate in the synthesis of RNA.; Cytidine 5'-(tetrahydrogen triphosphate) or CTP is a cytosine nucleotide containing three phosphate groups esterified to a ribose moiety at the 5' position. CTP is integral to the synthesis or mRNA, rRNA and tRNA through RNA polymerases. Cytidine triphosphate (CTP) is also critical to the synthesis of phosphatidylcholine via the enzyme CTP: phosphocholine cytidyltransferase. This reaction is the rate-limiting step in the synthesis of phosphatidylcholine.; Cytidine triphosphate is a pyrimidine nucleotide. 1wvc 5'-(Tetrahydrogen triate) cytidine 5'-(tetrahydrogen triphosphate) cytidine 5'-CTP CTP Cytidine 3'-triate Cytidine 3'-triphosphate Cytidine 5-prime-triate Cytidine 5-Prime-Triphosphate Cytidine 5'-(tetrahydrogen triate) cytidine 5'-(tetrahydrogen triphosphate) Cytidine 5'-(tetrahydrogen triphosphate) (8CI,9CI) Cytidine 5'-(tetrahydrogen triphosphate), 9CI Cytidine 5'-triate Cytidine 5'-triic acid Cytidine 5'-trioric acid Cytidine 5'-triphosphoric acid Cytidine mono Cytidine mono(tetrahydrogen triate) (ester) Cytidine mono(tetrahydrogen triphosphate) (ester) Cytidine triate Cytidine triic acid Cytidine triphosphate Cytidine triphosphic acid CYTIDINE-5'-triATE CYTIDINE-5'-triic acid cytidine-5'-triphosphate Cytidine, mono(tetrahydrogen triphosphate) (ester) Deoxycytosine triate Deoxycytosine triphosphate H4ctp C9H16N3O14P3 483.1563 482.984511771 ({[({[3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid ({[3,4-dihydroxy-5-(2-hydroxy-4-iminopyrimidin-1-yl)oxolan-2-yl]methoxy(hydroxy)phosphoryl}oxy(hydroxy)phosphoryl)oxyphosphonic acid 65-47-4 NC1=NC(=O)N(C=C1)C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O InChI=1S/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18) PCDQPRRSZKQHHS-UHFFFAOYSA-N belongs to the class of organic compounds known as pyrimidine ribonucleoside triphosphates. These are pyrimidine ribobucleotides with triphosphate group linked to the ribose moiety. Pyrimidine ribonucleoside triphosphates Organic compounds Nucleosides, nucleotides, and analogues Pyrimidine nucleotides Pyrimidine ribonucleotides Aromatic heteromonocyclic compounds 1,2-diols Aminopyrimidines and derivatives Azacyclic compounds Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Imidolactams Monoalkyl phosphates Monosaccharide phosphates Organic oxides Organopnictogen compounds Oxacyclic compounds Pentose phosphates Primary amines Pyrimidones Secondary alcohols Tetrahydrofurans 1,2-diol Alcohol Alkyl phosphate Amine Aminopyrimidine Aromatic heteromonocyclic compound Azacycle Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Imidolactam Monoalkyl phosphate Monosaccharide Monosaccharide phosphate N-glycosyl compound Organic nitrogen compound Organic oxide Organic oxygen compound Organic phosphoric acid derivative Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pentose monosaccharide Pentose phosphate Pentose-5-phosphate Phosphoric acid ester Primary amine Pyrimidine Pyrimidine ribonucleoside triphosphate Pyrimidone Secondary alcohol Tetrahydrofuran Solid logp -0.82 ALOGPS logs -1.83 ALOGPS solubility 7.13e+00 g/l ALOGPS melting_point 215-218 oC logp -4.3 ChemAxon pka_strongest_acidic 0.89 ChemAxon pka_strongest_basic 2.24 ChemAxon iupac ({[({[3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid ChemAxon average_mass 483.1563 ChemAxon mono_mass 482.984511771 ChemAxon smiles NC1=NC(=O)N(C=C1)C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ChemAxon formula C9H16N3O14P3 ChemAxon inchi InChI=1S/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18) ChemAxon inchikey PCDQPRRSZKQHHS-UHFFFAOYSA-N ChemAxon polar_surface_area 269.19 ChemAxon refractivity 98.58 ChemAxon polarizability 36.39 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 14 ChemAxon donor_count 8 ChemAxon physiological_charge -3 ChemAxon formal_charge 0 ChemAxon Amino Sugar Metabolism SMP00045 map00520 DNA Replication Fork SMP00477 Pyrimidine Metabolism SMP00046 map00240 Transcription/Translation SMP00019 Specdb::MsMs 73017 Specdb::MsMs 73018 Specdb::MsMs 73019 Specdb::MsMs 132093 Specdb::MsMs 132094 Specdb::MsMs 132095 Specdb::MsMs 3416255 Specdb::MsMs 3416256 Specdb::MsMs 3416257 Specdb::MsMs 3416258 Specdb::MsMs 3416259 Specdb::MsMs 3416260 Specdb::CMs 115253 Specdb::CMs 129559 Specdb::CMs 848031 Specdb::CMs 848032 Specdb::CMs 848033 Specdb::CMs 848034 Specdb::CMs 848035 Specdb::CMs 848036 Specdb::CMs 848037 Specdb::CMs 848038 Specdb::CMs 848039 Specdb::CMs 848040 Specdb::CMs 848041 Specdb::CMs 848042 Specdb::CMs 848043 Specdb::CMs 848044 Specdb::CMs 848045 Specdb::CMs 848046 Specdb::CMs 848047 Specdb::CMs 848048 Specdb::CMs 848049 Specdb::CMs 848050 Specdb::CMs 848051 Specdb::CMs 848052 Specdb::CMs 848053 Specdb::NmrOneD 210867 Specdb::NmrOneD 210868 Specdb::NmrOneD 210869 Specdb::NmrOneD 210870 Specdb::NmrOneD 210871 Specdb::NmrOneD 210872 Specdb::NmrOneD 210873 Specdb::NmrOneD 210874 Specdb::NmrOneD 210875 Specdb::NmrOneD 210876 Specdb::NmrOneD 210877 Specdb::NmrOneD 210878 Specdb::NmrOneD 210879 Specdb::NmrOneD 210880 Specdb::NmrOneD 210881 Specdb::NmrOneD 210882 Specdb::NmrOneD 210883 Specdb::NmrOneD 210884 Specdb::NmrOneD 210885 Specdb::NmrOneD 210886 HMDB00082 17677 CTP #<Reference:0x000055ce31aa72d8> #<Reference:0x000055ce31aa7120> #<Reference:0x000055ce31aa6f68> #<Reference:0x000055ce31aa6db0> #<Reference:0x000055ce31aa6bf8> #<Reference:0x000055ce31aa6a40> Milk and milk products Unknown generic Choline-phosphate cytidylyltransferase A P49585 PCYT1A Choline-phosphate cytidylyltransferase B Q9Y5K3 PCYT1B CTP synthase 2 Q9NRF8 CTPS2 DNA-directed RNA polymerase Q7Z3R8 DKFZp686D10173 DNA-directed RNA polymerase I subunit RPA1 O95602 POLR1A DNA-directed RNA polymerase I subunit RPA2 Q9H9Y6 POLR1B DNA-directed RNA polymerase I subunit RPA49 Q9GZS1 POLR1E DNA-directed RNA polymerase III subunit RPC1 O14802 POLR3A DNA-directed RNA polymerase III subunit RPC2 Q9NW08 POLR3B DNA-directed RNA polymerase III subunit RPC4 P05423 POLR3D DNA-directed RNA polymerase III subunit RPC7 O15318 POLR3G DNA-directed RNA polymerase III subunit RPC7-like Q9BT43 POLR3GL DNA-directed RNA polymerase III subunit RPC8 Q9Y535 POLR3H DNA-directed RNA polymerase, mitochondrial O00411 POLRMT DNA-directed RNA polymerases I and III subunit RPAC2 Q9Y2S0 POLR1D Dolichol kinase Q9UPQ8 DOLK Ethanolamine-phosphate cytidylyltransferase Q99447 PCYT2 N-acylneuraminate cytidylyltransferase Q8NFW8 CMAS Phosphatidate cytidylyltransferase 2 O95674 CDS2 Phosphopantothenate--cysteine ligase Q9HAB8 PPCS POLR1C protein Q96HT3 POLR1C Zinc ribbon domain containing 1 Q2L6J2 ZNRD1