1.0 2010-04-08 22:10:27 UTC 2025-11-18 23:40:26 UTC FDB012974 Mercenene Isolated from the common clam Mercenaria mercenaria and from Mercenaria campechiensis Carmustine is one of the nitrosoureas indicated as palliative therapy as a single agent or in established combination therapy with other approved chemotherapeutic agents in treatment of brain tumors, multiple myeloma, Hodgkin's disease, and non-Hodgkin's lymphomas. Although it is generally agreed that carmustine alkylates DNA and RNA, it is not cross resistant with other alkylators. As with other nitrosoureas, it may also inhibit several key enzymatic processes by carbamoylation of amino acids in proteins. Mercenene is found in mollusks. 1,3-Bis(2-Chloroethyl)-1-Nitrosourea 1,3-Bis(2-chloroethyl)nitrosourea 1,3-Bis(beta-chloroethyl)-1-nitrosourea 1,3-BIS(CHLOROETHYL)-1-NITROSOUREA BCNU Bcnu [chloroethyl nitrosoureas] Becenum Bi cnu Bicnu Bicnu (TN) Bis-n,n'-(chloroethyl)nitrosourea Bis(2-chloroethyl)1-nitrosourea Bis(2-chloroethyl)nitrosourea Bis(chloroethyl)nitrosourea Bischlorethylnitrosourea Bischlorethylnitrosurea Bischloroethyl nitrosourea Bischloroethyl nitrosourea [chloroethyl nitrosoureas] Bischloroethylnitrosourea Carmubris Carmustin Carmustina Carmustine Carmustine (usan/inn) Carmustine [usan:inn:ban] Carmustine in ethanol Carmustinum FIVB Gliadel N,N'-Bis(2-Chloroethyl)-N-Nitrosourea Nitrumon Urea, 1,3-bis(2-chloroethyl)-1-nitroso- Urea, N,N'-bis(2-chloroethyl)-N-nitroso- C5H9Cl2N3O2 214.05 213.007181961 1,3-bis(2-chloroethyl)-3-nitrosourea carmustine 154-93-8 ClCCNC(=O)N(CCCl)N=O InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11) DLGOEMSEDOSKAD-UHFFFAOYSA-N belongs to the class of organic compounds known as nitrosoureas. Nitrosoureas are compounds containing a nitro group and an urea group N-N linked together, with the general structure R1N(R2)C(=O)N(R3)N=O. Nitrosoureas Organic compounds Organic acids and derivatives Organic carbonic acids and derivatives Ureas Aliphatic acyclic compounds Alkyl chlorides Carbonyl compounds Hydrocarbon derivatives Nitrosamides Organic oxides Organochlorides Organopnictogen compounds Semicarbazides Aliphatic acyclic compound Alkyl chloride Alkyl halide Carbonyl group Hydrocarbon derivative Nitrosamide Nitrosourea Organic n-nitroso compound Organic nitrogen compound Organic nitroso compound Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Semicarbazide N-nitrosoureas organochlorine compound Solid logp 1.24 ALOGPS logs -2.15 ALOGPS solubility 1.53e+00 g/l ALOGPS logp 1.02 ChemAxon pka_strongest_acidic 11.96 ChemAxon pka_strongest_basic -5.3 ChemAxon iupac 1,3-bis(2-chloroethyl)-3-nitrosourea ChemAxon average_mass 214.05 ChemAxon mono_mass 213.007181961 ChemAxon smiles ClCCNC(=O)N(CCCl)N=O ChemAxon formula C5H9Cl2N3O2 ChemAxon inchi InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11) ChemAxon inchikey DLGOEMSEDOSKAD-UHFFFAOYSA-N ChemAxon polar_surface_area 61.77 ChemAxon refractivity 46.98 ChemAxon polarizability 18.8 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 21509 Specdb::CMs 130538 Specdb::CMs 138272 Specdb::MsMs 51651 Specdb::MsMs 51652 Specdb::MsMs 51653 Specdb::MsMs 158934 Specdb::MsMs 158935 Specdb::MsMs 158936 Specdb::MsMs 2471178 Specdb::MsMs 2471179 Specdb::MsMs 2471180 Specdb::MsMs 2493905 Specdb::MsMs 2493906 Specdb::MsMs 2493907 HMDB14407 3423 Mollusks Unknown generic 6447