Record Information
Version1.0
Creation date2010-04-08 22:10:37 UTC
Update date2019-11-26 03:08:15 UTC
Primary IDFDB013270
Secondary Accession Numbers
  • FDB013271
Chemical Information
FooDB NameTomatidine
DescriptionTomatidine belongs to the class of organic compounds known as spirosolanes and derivatives. These are steroidal alkaloids with a structure containing a spirosolane skeleton. Siporosolane is a polycyclic compound that is characterized by a 1-oxa-6-azaspiro[4.5]decane moiety where the oxolane ring is fused to a docosahydronaphth[2,1:4',5']indene ring system. Spirosolane arises from the conversion of a cholestane side-chain into a bicyclic system containing a piperidine and a tetrahydrofuran ring. Based on a literature review a significant number of articles have been published on Tomatidine.
CAS Number77-59-8
Structure
Thumb
Synonyms
SynonymSource
(22S,25S)-5alpha-Spirosolan-3beta-olHMDB
(3beta,5alpha,22beta,25S)-Spirosolan-3-olHMDB
(3beta,5alpha,25S)-Spirosolan-3-olHMDB
5a-Tomatidan-3b-ol, 8ciHMDB
5alpha -Tomatidan-3beta -olHMDB
5alpha-Tomatidan-3beta-olHMDB
5alpha-Tomatidan-3beta-ol (8ci)HMDB
Spirosolan-3-olHMDB
Spirosolan-3-ol, (3alpha ,22alpha -tomatidan-3beta -olHMDB
Spirosolan-3-ol, (3beta,5alpha,22beta,25S)- (9ci)HMDB
TomatidinHMDB
SoladulcidineMeSH
Tomatidine, (3beta,5alpha,22alpha,25R)-isomerMeSH
5 alpha,20 beta(F),22 alpha(F),25 beta(F),27- Azaspirostan-3 beta-olMeSH
(22S,25S)-5alpha-spirosolan-3beta-olbiospider
(3beta,5alpha,22beta,25S)-spirosolan-3-olbiospider
(3beta,5alpha,25S)-spirosolan-3-olbiospider
5α-Tomatidan-3β-olbiospider
5a-Tomatidan-3b-ol, 8CIdb_source
5alpha-tomatidan-3beta-olbiospider
5alpha-Tomatidan-3beta-ol (8CI)biospider
Spirosolan-3-ol, (3α,22α-Tomatidan-3β-olbiospider
Spirosolan-3-ol, (3β,5α,22β,25S)-biospider
Spirosolan-3-ol, (3beta,5alpha,22beta,25S)-biospider
Spirosolan-3-ol, (3beta,5alpha,22beta,25S)- (9CI)biospider
Tomatidinedb_source
Predicted PropertiesNot Available
Chemical FormulaC27H45NO2
IUPAC name
InChI IdentifierInChI=1S/C27H45NO2/c1-16-7-12-27(28-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(29)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28-29H,5-15H2,1-4H3
InChI KeyXYNPYHXGMWJBLV-UHFFFAOYSA-N
Isomeric SMILESCC1C2C(CC3C4CCC5CC(O)CCC5(C)C4CCC23C)OC11CCC(C)CN1
Average Molecular Weight415.6517
Monoisotopic Molecular Weight415.345029689
Classification
Description Belongs to the class of organic compounds known as spirosolanes and derivatives. These are steroidal alkaloids with a structure containing a spirosolane skeleton. Siporosolane is a polycyclic compound that is characterized by a 1-oxa-6-azaspiro[4.5]Decane moiety where the oxolane ring is fused to a docosahydronaphth[2,1:4',5']Indene ring system. Spirosolane arises from the conversion of a cholestane side-chain into a bicyclic system containing a piperidine and a tetrahydrofuran ring.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassSteroids and steroid derivatives
Sub ClassSteroidal alkaloids
Direct ParentSpirosolanes and derivatives
Alternative Parents
Substituents
  • Spirosolane skeleton
  • 3-hydroxysteroid
  • Hydroxysteroid
  • Azasteroid
  • Azaspirodecane
  • Alkaloid or derivatives
  • Piperidine
  • Tetrahydrofuran
  • Cyclic alcohol
  • Secondary alcohol
  • Hemiaminal
  • Organoheterocyclic compound
  • Oxacycle
  • Secondary amine
  • Azacycle
  • Secondary aliphatic amine
  • Organic nitrogen compound
  • Hydrocarbon derivative
  • Organonitrogen compound
  • Organooxygen compound
  • Organopnictogen compound
  • Organic oxygen compound
  • Amine
  • Alcohol
  • Aliphatic heteropolycyclic compound
Molecular FrameworkAliphatic heteropolycyclic compounds
External DescriptorsNot Available
Ontology
Disposition

Route of exposure:

Biological location:

Source:

Process

Naturally occurring process:

Role

Industrial application:

Biological role:

Foods

Fruits and vegetables:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateNot Available
Physical DescriptionNot Available
Mass CompositionC 78.02%; H 10.91%; N 3.37%; O 7.70%DFC
Melting PointMp 210-211°DFC
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical Rotation[a]20D +5 (MeOH)DFC
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
EI-MS/GC-MSNot Available
MS/MSNot Available
NMRNot Available
ChemSpider IDNot Available
ChEMBL IDNot Available
KEGG Compound IDC10826
Pubchem Compound ID65576
Pubchem Substance IDNot Available
ChEBI ID9629
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDNot Available
CRC / DFC (Dictionary of Food Compounds) IDHHM52-S:HQO35-K
EAFUS IDNot Available
Dr. Duke IDTOMATIDINE
BIGG IDNot Available
KNApSAcK IDC00002267
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDNot Available
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / Bioactivities
DescriptorIDDefinitionReference
anti feedantDUKE
pesticide25944 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.DUKE
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference— Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004).
— Shinbo, Y., et al. 'KNApSAcK: a comprehensive species-metabolite relationship database.' Plant Metabolomics. Springer Berlin Heidelberg, 2006. 165-181.