Record Information
Version1.0
Creation date2010-04-08 22:10:41 UTC
Update date2015-07-20 22:58:42 UTC
Primary IDFDB013394
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameHydrazine
DescriptionFood contaminant arising from its use as a boiler water additive in production of steam used in food processing Being bifunctional, with two amines, hydrazine is a key building block for the preparation of many heterocyclic compounds via condensation with a range of difunctional electrophiles. With 2,4-pentanedione, it condenses to give the 3,5-dimethylpyrazole. In the Einhorn-Brunner reaction hydrazines react with imides to give triazoles.; Hydrazine is a convenient reductant because the by-products are typically nitrogen gas and water. Thus, it is used as an antioxidant, an oxygen scavenger, and a corrosion inhibitor in water boilers and heating systems. It is also used to reduce metal salts and oxides to the pure metals in electroless nickel plating and plutonium extraction from nuclear reactor waste.; Hydrazine is an inorganic chemical compound with the formula N2H4. It is a colourless liquid with an ammonia-like odor and is derived from the same industrial chemistry processes that manufacture ammonia. However, hydrazine has physical properties that are more similar to those of water.; The propanone azine is an intermediate in the Atofina-PCUK synthesis. Direct alkylation of hydrazines with alkyl halides in the presence of base affords alkyl-substituted hydrazines, but the reaction is typically inefficient due to poor control on level of substitution (same as in ordinary amines). The reduction of hydrazones to hydrazines present a clean way to produce 1,1-dialkylated hydrazines.
CAS Number302-01-2
Structure
Thumb
Synonyms
SynonymSource
DiamineChEBI
H2NNH2ChEBI
HydrazinChEBI
N2H4ChEBI
Nitrogen hydrideChEBI
AmerzineHMDB
Catalyzed hydrazineHMDB
DiamideHMDB
DiazaneHMDB
HDZHMDB
Hydrazine (anhydrous)HMDB
Hydrazine (hydrazine sulfate)HMDB
Hydrazine (hydrazine sulphate)HMDB
Hydrazine baseHMDB
Hydrazine solutionHMDB
HydrazinesHMDB
HydrazynaHMDB
LevoxineHMDB
Oxytreat 35HMDB
Scav-ox IIHMDB
ZeroxHMDB
Hydrazine mononitrateHMDB
Hydrazine phosphate (2:1)HMDB
SegidrinHMDB
Hydrazine dihydrochlorideHMDB
Hydrazine monohydrateHMDB
Hydrazine sulfateHMDB
Hydrazine tartrateHMDB
Hydrazine phosphate (1:1)HMDB
Hydrazine sulfate (2:1)HMDB
Hydrazine hydrateHMDB
Hydrazine nitrateHMDB
Hydrazine sulfate (1:1) monosodium saltHMDB
Hydrazine, anhydrousbiospider
Hydrazine/hydrazine sulfatebiospider
Ultra purebiospider
Predicted Properties
PropertyValueSource
logP-1ChemAxon
pKa (Strongest Basic)5.4ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area52.04 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity10.57 m³·mol⁻¹ChemAxon
Polarizability3.25 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Chemical FormulaH4N2
IUPAC namehydrazine
InChI IdentifierInChI=1S/H4N2/c1-2/h1-2H2
InChI KeyOAKJQQAXSVQMHS-UHFFFAOYSA-N
Isomeric SMILESNN
Average Molecular Weight32.0452
Monoisotopic Molecular Weight32.037448138
Classification
Description belongs to the class of inorganic compounds known as homogeneous other non-metal compounds. These are inorganic non-metallic compounds in which the largest atom belongs to the class of 'other non-metals'.
KingdomInorganic compounds
Super ClassHomogeneous non-metal compounds
ClassHomogeneous other non-metal compounds
Sub ClassNot Available
Direct ParentHomogeneous other non-metal compounds
Alternative Parents
Substituents
  • Homogeneous other non metal
  • Hydrazine derivative
Molecular FrameworkNot Available
External Descriptors
Ontology
Physiological effect

Health effect:

Disposition

Route of exposure:

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Process

Industrial process:

Role

Industrial application:

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Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateLiquid
Physical DescriptionNot Available
Mass CompositionH 12.58%; N 87.42%DFC
Melting PointMp 1.8°DFC
Boiling PointBp 113.5°DFC
Experimental Water Solubility1000 mg/mLAMOORE,JE & HAUTALA,E (1983)
Experimental logP-2.07HANSCH,C ET AL. (1995)
Experimental pKapKa 7.96DFC
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
Densityd25 1DFC
Refractive Indexn25D 1.4640DFC
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyView
Predicted GC-MSPredicted GC-MS Spectrum - GC-MS (Non-derivatized) - 70eV, Positivesplash10-001i-9000000000-7e6c9f4fe38a72218c48JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-001i-9000000000-401f7c59e214d2145c6bJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-001i-9000000000-401f7c59e214d2145c6bJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-001i-9000000000-401f7c59e214d2145c6bJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-001i-9000000000-d34c4424b02bfa4ea545JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-001i-9000000000-d34c4424b02bfa4ea545JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-001i-9000000000-d34c4424b02bfa4ea545JSpectraViewer
ChemSpider ID8960
ChEMBL IDCHEMBL1237174
KEGG Compound IDC05361
Pubchem Compound ID9321
Pubchem Substance IDNot Available
ChEBI ID15571
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB12973
CRC / DFC (Dictionary of Food Compounds) IDHVD28-Q:HVD28-Q
EAFUS ID1716
Dr. Duke IDNot Available
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDHydrazine
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSshow
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference