Record Information |
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Version | 1.0 |
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Creation date | 2010-04-08 22:10:55 UTC |
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Update date | 2020-09-17 15:38:52 UTC |
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Primary ID | FDB013802 |
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Secondary Accession Numbers | Not Available |
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Chemical Information |
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FooDB Name | Lanosterol |
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Description | Lanosterin, also known as botalan base 138 or lanosterol, belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. Thus, lanosterin is considered to be a sterol lipid molecule. Lanosterin is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. |
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CAS Number | 79-63-0 |
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Structure | |
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Synonyms | Synonym | Source |
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(3beta)-Lanosta-8,24-dien-3-ol | ChEBI | (3beta,5alpha)-4,4,14-Trimethylcholesta-8,24-dien-3-ol | ChEBI | 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol | ChEBI | (3b)-Lanosta-8,24-dien-3-ol | Generator | (3β)-Lanosta-8,24-dien-3-ol | Generator | (3b,5a)-4,4,14-Trimethylcholesta-8,24-dien-3-ol | Generator | (3β,5α)-4,4,14-Trimethylcholesta-8,24-dien-3-ol | Generator | 4,4',14a-Trimethyl-5a-cholesta-8,24-dien-3b-ol | Generator | 4,4',14α-Trimethyl-5α-cholesta-8,24-dien-3β-ol | Generator | (3 beta)-Lanosta-8,24-dien-3-ol | HMDB | (3alpha)-4,4,14-Trimethyl-cholesta-8,24-dien-3-ol | HMDB | (3beta,5alpha)-4,4,14-Trimethyl-cholesta-8,24-dien-3-ol | HMDB | Botalan base 138 | HMDB | Lanosta-8,24-dien-3-ol | HMDB | Lanosta-8,24-dien-3beta-ol | HMDB | Lanosta-8,24-dienol | HMDB | Lanosterol | HMDB | Lanster | HMDB | 4,4,14 alpha-Trimethyl-5 alpha-cholesta-8,24-dien-3 beta-ol | MeSH, HMDB | Kryptosterol | MeSH, HMDB | Lanosterin | ChEBI | 3beta-Hydroxy-lansota-8,24-dien-21-oic acid | HMDB | 3beta-Hydroxylanosta-8,24-diene | HMDB | 3β-Hydroxy-lansota-8,24-dien-21-oic acid | HMDB | 3β-Hydroxylanosta-8,24-diene | HMDB | 4,4,14alpha-Trimethylcholesta-8,24-dien-3beta-ol | HMDB | 4,4,14α-Trimethylcholesta-8,24-dien-3β-ol | HMDB | 5alpha-Lanosta-8,24-dien-3beta-ol | HMDB | 5α-Lanosta-8,24-dien-3β-ol | HMDB | Lanosta-8,24-dien-3β-ol | HMDB | Lanostadien-3beta-ol | HMDB | Lanostadien-3β-ol | HMDB | (3beta,5alpha)-4,4,14-trimethyl-cholesta-8,24-dien-3-ol | biospider | (3β,5α)-4,4,14-trimethylcholesta-8,24-dien-3-ol | Generator | (3β)-lanosta-8,24-dien-3-ol | Generator | 3beta-Hydroxy-8,24-lanostadiene | biospider | 4,4',14α-trimethyl-5α-cholesta-8,24-dien-3β-ol | Generator | 8,24-Lanostadien-3beta-ol | biospider | Cryptosterol | db_source | Isocholesterol | db_source | Lanosta-8,24-dien-3-ol, (3β)- | biospider | Lanosta-8,24-dien-3β-ol | biospider |
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Predicted Properties | |
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Chemical Formula | C30H50O |
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IUPAC name | (2S,5S,7R,11R,14R,15R)-2,6,6,11,15-pentamethyl-14-[(2R)-6-methylhept-5-en-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-1(10)-en-5-ol |
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InChI Identifier | InChI=1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1 |
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InChI Key | CAHGCLMLTWQZNJ-BQNIITSRSA-N |
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Isomeric SMILES | [H][C@@]1(CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@]1([H])CC3)[C@H](C)CCC=C(C)C |
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Average Molecular Weight | 426.7174 |
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Monoisotopic Molecular Weight | 426.386166222 |
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Classification |
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Description | Belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Prenol lipids |
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Sub Class | Triterpenoids |
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Direct Parent | Triterpenoids |
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Alternative Parents | |
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Substituents | - Triterpenoid
- 14-alpha-methylsteroid
- 3-beta-hydroxysteroid
- Hydroxysteroid
- 3-hydroxysteroid
- Steroid
- Cyclic alcohol
- Secondary alcohol
- Organic oxygen compound
- Hydrocarbon derivative
- Organooxygen compound
- Alcohol
- Aliphatic homopolycyclic compound
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Molecular Framework | Aliphatic homopolycyclic compounds |
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External Descriptors | |
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Ontology |
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Disposition | Route of exposure: Source: Biological location: |
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Process | Naturally occurring process: |
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Role | Biological role: Industrial application: |
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Physico-Chemical Properties - Experimental |
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Physico-Chemical Properties - Experimental | Property | Value | Reference |
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Physical state | Solid | |
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Physical Description | Not Available | |
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Mass Composition | C 84.44%; H 11.81%; O 3.75% | DFC |
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Melting Point | Mp 140-141° | DFC |
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Boiling Point | Not Available | |
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Experimental Water Solubility | Not Available | |
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Experimental logP | Not Available | |
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Experimental pKa | Not Available | |
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Isoelectric point | Not Available | |
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Charge | 0 | |
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Optical Rotation | [a]17D +58 (CHCl3) | DFC |
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Spectroscopic UV Data | Not Available | |
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Density | Not Available | |
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Refractive Index | Not Available | |
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Spectra |
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Spectra | |
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EI-MS/GC-MS | Type | Description | Splash Key | View |
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EI-MS | Mass Spectrum (Electron Ionization) | splash10-05mo-9731200000-b1bc6bb68e352e3bd687 | 2015-03-01 | View Spectrum | GC-MS | Lanosterol, 1 TMS, GC-MS Spectrum | splash10-0a4l-4910000000-0fe7f84c95ab0a849fe9 | Spectrum | GC-MS | Lanosterol, non-derivatized, GC-MS Spectrum | splash10-03dl-2953300000-ae1832f19369485ff53c | Spectrum | GC-MS | Lanosterol, non-derivatized, GC-MS Spectrum | splash10-0aou-9820200000-573525b346ad3c9eef59 | Spectrum | GC-MS | Lanosterol, non-derivatized, GC-MS Spectrum | splash10-0a4l-4910000000-0fe7f84c95ab0a849fe9 | Spectrum | GC-MS | Lanosterol, non-derivatized, GC-MS Spectrum | splash10-0a4l-2910000000-c67a1f122f33698a14f6 | Spectrum | Predicted GC-MS | Lanosterol, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | splash10-03dj-1009400000-e2b516142f5128a7b5f6 | Spectrum | Predicted GC-MS | Lanosterol, 1 TMS, Predicted GC-MS Spectrum - 70eV, Positive | splash10-001i-3002900000-35e63c0bf6f033cb847c | Spectrum | Predicted GC-MS | Lanosterol, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum | Predicted GC-MS | Lanosterol, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum |
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MS/MS | Type | Description | Splash Key | View |
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MS/MS | LC-MS/MS Spectrum - n/a 1V, positive | splash10-0a6r-0110900000-5e42e1f2d9ad534c003c | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 13V, positive | splash10-0a4i-0230900000-10f58fa6e118cd7c5997 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 17V, positive | splash10-0a4i-1791800000-178153ad92eececb33c4 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 20V, positive | splash10-0a4i-2980300000-6ce95c7f8b15b35475af | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 23V, positive | splash10-0a4j-2950100000-48f86ff7a22c596aa44d | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 27V, positive | splash10-0592-3940000000-c35d0cb6a2e4e291e8f8 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 30V, positive | splash10-0592-3920000000-d717fdd3322a881bef99 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 34V, positive | splash10-0592-4910000000-4c6d07e3a8e48ae88580 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 41V, positive | splash10-0a4j-5900000000-4c8b72037dbeae9a46d1 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 52V, positive | splash10-067m-8900000000-522b8688d50362297c41 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 62V, positive | splash10-0aou-9700000000-70d433827c1a6dab0c41 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 76V, positive | splash10-05ox-9500000000-5b122dea636d3e3b5916 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 90V, positive | splash10-05r3-9500000000-0c1c5cbd994f8406f30e | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - Orbitrap 111V, positive | splash10-05r3-9600000000-5cb8ae11d071fa19f206 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - n/a 29V, positive | splash10-0ktf-0392000000-03cda521ce6e102d92e4 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - n/a 29V, positive | splash10-059j-2900000000-8086693fb040e5ed7501 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - n/a 29V, positive | splash10-0a4i-4900000000-c58ff2dc28c6ba639997 | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - n/a 29V, positive | splash10-01vk-0900000000-805937445cceda0cd70a | 2020-07-22 | View Spectrum | MS/MS | LC-MS/MS Spectrum - n/a 29V, positive | splash10-0aor-0900000000-22d304b445b737121aa7 | 2020-07-22 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0a6r-0002900000-2cfcf7ce4b5b21140eae | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0pdi-2139500000-9a25961000db9796d6da | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0uxr-4259100000-9f7f26265abec4122e35 | 2016-08-01 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-004i-0000900000-77a57cecc2069bee1926 | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-004i-0000900000-5b0f06bf8120e780e30c | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-0a4l-1009400000-421e305d47b29da427d2 | 2016-08-03 | View Spectrum |
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NMR | Type | Description | | View |
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1D NMR | 13C NMR Spectrum (1D, 100 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 100 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 1000 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 1000 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 200 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 200 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 300 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 300 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 400 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 400 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 500 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 500 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 600 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 600 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 700 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 700 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 800 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 800 MHz, H2O, predicted) | | Spectrum | 1D NMR | 13C NMR Spectrum (1D, 900 MHz, H2O, predicted) | | Spectrum | 1D NMR | 1H NMR Spectrum (1D, 900 MHz, H2O, predicted) | | Spectrum |
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External Links |
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ChemSpider ID | 216175 |
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ChEMBL ID | CHEMBL225111 |
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KEGG Compound ID | C01724 |
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Pubchem Compound ID | 246983 |
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Pubchem Substance ID | Not Available |
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ChEBI ID | 16521 |
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Phenol-Explorer ID | Not Available |
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DrugBank ID | Not Available |
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HMDB ID | HMDB01251 |
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CRC / DFC (Dictionary of Food Compounds) ID | JHN22-K:JHN22-K |
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EAFUS ID | Not Available |
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Dr. Duke ID | LANOSTEROL |
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BIGG ID | 38253 |
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KNApSAcK ID | C00003657 |
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HET ID | LAN |
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Food Biomarker Ontology | Not Available |
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VMH ID | Not Available |
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Flavornet ID | Not Available |
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GoodScent ID | Not Available |
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SuperScent ID | Not Available |
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Wikipedia ID | Lanosterol |
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Phenol-Explorer Metabolite ID | Not Available |
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Duplicate IDS | Not Available |
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Old DFC IDS | Not Available |
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Associated Foods |
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Food | Content Range | Average | Reference |
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Food | | | Reference |
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Biological Effects and Interactions |
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Health Effects / Bioactivities | |
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Enzymes | Name | Gene Name | UniProt ID |
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Lanosterol synthase | LSS | P48449 |
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Pathways | |
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Metabolism | Not Available |
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Biosynthesis | Not Available |
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Organoleptic Properties |
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Flavours | Not Available |
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Files |
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MSDS | show |
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References |
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Synthesis Reference | Not Available |
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General Reference | Not Available |
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Content Reference | — Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004). — Shinbo, Y., et al. 'KNApSAcK: a comprehensive species-metabolite relationship database.' Plant Metabolomics. Springer Berlin Heidelberg, 2006. 165-181.
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