<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2010-04-08 22:11:49 UTC</creation_date>
  <update_date>2025-11-19 00:54:46 UTC</update_date>
  <accession>FDB015402</accession>
  <name>Calcium sulfate</name>
  <description>It is used in foods as an anticaking agent, colouring adjunct, dough strengthener, drying agent, firming agent, formulation aid, leavening agent, nutrient supplement, pH control agent, processing aid, stabiliser, thickener, synergist and texturiser; also used as an additive in the bleaching of flour by benzoyl peroxide

Calcium sulfate is a common component of fouling deposits in industrial heat exchangers. It is because its solubility decreases with increasing temperature in hot water (see the figure).; Calcium sulfate is a common laboratory and industrial chemical. In the form of ?-anhydrite (the nearly anhydrous form), it is used as a desiccant. It is also used as a coagulant in products like tofu. In the natural state, unrefined calcium sulfate is a translucent, crystalline white rock. When sold as a color-indicating variant under the name Drierite, it appears blue or pink due to impregnation with cobalt chloride, which functions as a moisture indicator. The hemihydrate (CaSO4.~0.5H2O) is better known as plaster of Paris, while the dihydrate (CaSO4.2H2O) occurs naturally as gypsum. The anhydrous form occurs naturally as ?-anhydrite. Depending on the method of calcination of calcium sulfate dihydrate, specific hemihydrates are sometimes distinguished: alpha-hemihydrate and beta-hemihydrate. They appear to differ only in crystal size. Alpha-hemihydrate crystals are more prismatic than beta-hemihydrate crystals and, when mixed with water, form a much stronger and harder superstructure.</description>
  <synonyms>
    <synonym>Anhydrite</synonym>
    <synonym>Anhydrous calcium sulfate</synonym>
    <synonym>Anhydrous gypsum</synonym>
    <synonym>Anhydrous sulfate of lime</synonym>
    <synonym>Basic calcium sulfate</synonym>
    <synonym>Calc Sulph Pwr 6x</synonym>
    <synonym>Calc sulph schuessler cell salt homaccord</synonym>
    <synonym>Calcarea Sulfurica 2ch-30ch</synonym>
    <synonym>Calcarea Sulph 6x</synonym>
    <synonym>Calcarea sulphurica</synonym>
    <synonym>Calcined gypsum</synonym>
    <synonym>Calcium sulfate (1:1)</synonym>
    <synonym>Calcium sulfate (CaSO4)</synonym>
    <synonym>Calcium sulfate (NF)</synonym>
    <synonym>Calcium Sulfate Liquid (S#114)</synonym>
    <synonym>Calcium sulfate, anhydrous</synonym>
    <synonym>Calcium sulfuricum</synonym>
    <synonym>Calcium Sulfuricum-Injeel Forte Liq (6d,12d,30d,200d/1.1ml)</synonym>
    <synonym>Calcium sulphate</synonym>
    <synonym>Calcium sulphate, natural</synonym>
    <synonym>CaSO4</synonym>
    <synonym>Crysalba</synonym>
    <synonym>Drierite</synonym>
    <synonym>Drierite(r)</synonym>
    <synonym>E516</synonym>
    <synonym>Exsiccated gypsum</synonym>
    <synonym>Exsiccated gypsum (JP15)</synonym>
    <synonym>Franklin Fiber H 45</synonym>
    <synonym>GIBS</synonym>
    <synonym>Gypsum</synonym>
    <synonym>Gypsum (JP15)</synonym>
    <synonym>Gypsum fibrosum</synonym>
    <synonym>Gypsum fibrosum (TN)</synonym>
    <synonym>Kalziumsulfat</synonym>
    <synonym>Karstenite</synonym>
    <synonym>Muriacite</synonym>
    <synonym>Natural anhydrite</synonym>
    <synonym>Oparex 10</synonym>
    <synonym>Osteoset</synonym>
    <synonym>Pigment white 25</synonym>
    <synonym>Plaster of paris</synonym>
    <synonym>Plaster of paris, anhydrite</synonym>
    <synonym>S3 Calcarea Sulphurica</synonym>
    <synonym>Satin white</synonym>
    <synonym>SSS-a</synonym>
    <synonym>Sulfuric acid calcium salt, 8CI</synonym>
    <synonym>Sulfuric acid, calcium salt</synonym>
    <synonym>Sulfuric acid, calcium salt (1:1)</synonym>
    <synonym>Sulfuric acid, calcium salt (van)</synonym>
    <synonym>Surfuric acid calcium(2+) salt (1:1)</synonym>
    <synonym>Terra alba</synonym>
    <synonym>Thiolite</synonym>
  </synonyms>
  <chemical_formula>CaO4S</chemical_formula>
  <average_molecular_weight>136.141</average_molecular_weight>
  <monisotopic_moleculate_weight>135.914320333</monisotopic_moleculate_weight>
  <iupac_name>calcium sulfate</iupac_name>
  <traditional_iupac>calcium sulfate</traditional_iupac>
  <cas_registry_number>7778-18-9</cas_registry_number>
  <smiles>[Ca++].[O-]S([O-])(=O)=O</smiles>
  <inchi>InChI=1S/Ca.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2</inchi>
  <inchikey>OSGAYBCDTDRGGQ-UHFFFAOYSA-L</inchikey>
  <taxonomy>
    <description> belongs to the class of inorganic compounds known as alkaline earth metal sulfates. These are inorganic compounds in which the largest oxoanion is sulfate, and in which the heaviest atom not in an oxoanion is an alkaline earth metal.</description>
    <direct_parent>Alkaline earth metal sulfates</direct_parent>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Mixed metal/non-metal compounds</super_class>
    <class>Alkaline earth metal oxoanionic compounds</class>
    <sub_class>Alkaline earth metal sulfates</sub_class>
    <molecular_framework/>
    <alternative_parents>
      <alternative_parent>Inorganic calcium salts</alternative_parent>
      <alternative_parent>Inorganic oxides</alternative_parent>
    </alternative_parents>
    <substituents>
      <substituent>Alkaline earth metal sulfate</substituent>
      <substituent>Inorganic calcium salt</substituent>
      <substituent>Inorganic oxide</substituent>
      <substituent>Inorganic salt</substituent>
    </substituents>
    <external_descriptors>
      <external_descriptor>calcium salt</external_descriptor>
    </external_descriptors>
  </taxonomy>
  <state/>
  <predicted_properties>
  </predicted_properties>
  <experimental_properties>
    <property>
      <kind>melting_point</kind>
      <value>Mp 1570°</value>
    </property>
  </experimental_properties>
  <property>
    <kind>logp</kind>
    <value>-0.84</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>pka_strongest_acidic</kind>
    <value>-3</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>iupac</kind>
    <value>calcium sulfate</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>average_mass</kind>
    <value>136.141</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>mono_mass</kind>
    <value>135.914320333</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>smiles</kind>
    <value>[Ca++].[O-]S([O-])(=O)=O</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>formula</kind>
    <value>CaO4S</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>inchi</kind>
    <value>InChI=1S/Ca.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>inchikey</kind>
    <value>OSGAYBCDTDRGGQ-UHFFFAOYSA-L</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>polar_surface_area</kind>
    <value>80.26</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>refractivity</kind>
    <value>11.53</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>polarizability</kind>
    <value>5.81</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>rotatable_bond_count</kind>
    <value>0</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>acceptor_count</kind>
    <value>4</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>donor_count</kind>
    <value>0</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>physiological_charge</kind>
    <value>-2</value>
    <source>ChemAxon</source>
  </property>
  <property>
    <kind>formal_charge</kind>
    <value>0</value>
    <source>ChemAxon</source>
  </property>
  <pathways>
  </pathways>
  <spectra>
    <spectrum>
      <type>Specdb::MsMs</type>
      <spectrum_id>1310233</spectrum_id>
    </spectrum>
    <spectrum>
      <type>Specdb::MsMs</type>
      <spectrum_id>1310234</spectrum_id>
    </spectrum>
    <spectrum>
      <type>Specdb::MsMs</type>
      <spectrum_id>1310235</spectrum_id>
    </spectrum>
  </spectra>
  <hmdb_id/>
  <pubchem_compound_id/>
  <chemspider_id/>
  <kegg_id/>
  <chebi_id>31346</chebi_id>
  <biocyc_id/>
  <het_id/>
  <wikipidia/>
  <vmh_id/>
  <fbonto_id/>
  <foodb_id/>
  <general_references>
  </general_references>
  <foods>
  </foods>
  <flavors>
    <flavor>
      <name>odorless</name>
    </flavor>
  </flavors>
  <enzymes>
  </enzymes>
  <health_effects>
  </health_effects>
</compound>
