1.0 2010-04-08 22:11:52 UTC 2025-11-19 00:55:37 UTC FDB015495 Tetramethylpyrazine Tetramethylpyrazine is isolated from galbanum oil. It is found in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products, orange bell pepper and soy products. Used as a fragrance and flavouring ingredient. 2,3,5,6-Tetramethylpyrazine Chuanxiongzine FEMA 3237 Ligustizine Ligustrazine Tetramethylpyrazin Tetrapyrazine TMP? C8H12N2 136.1943 136.100048394 tetramethylpyrazine pyrazine, tetramethyl- 1124-11-4 CC1=NC(C)=C(C)N=C1C InChI=1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3 FINHMKGKINIASC-UHFFFAOYSA-N belongs to the class of organic compounds known as pyrazines. Pyrazines are compounds containing a pyrazine ring, which is a six-member aromatic heterocycle, that consists of two nitrogen atoms (at positions 1 and 4) and four carbon atoms. Pyrazines Organic compounds Organoheterocyclic compounds Diazines Pyrazines Aromatic heteromonocyclic compounds Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Organonitrogen compounds Organopnictogen compounds Aromatic heteromonocyclic compound Azacycle Heteroaromatic compound Hydrocarbon derivative Organic nitrogen compound Organonitrogen compound Organopnictogen compound Pyrazine logp 1.46 ALOGPS logs -0.96 ALOGPS solubility 1.50e+01 g/l ALOGPS melting_point Mp 86° (anhyd.) logp 0.063 ChemAxon pka_strongest_basic 2.19 ChemAxon iupac tetramethylpyrazine ChemAxon average_mass 136.1943 ChemAxon mono_mass 136.100048394 ChemAxon smiles CC1=NC(C)=C(C)N=C1C ChemAxon formula C8H12N2 ChemAxon inchi InChI=1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3 ChemAxon inchikey FINHMKGKINIASC-UHFFFAOYSA-N ChemAxon polar_surface_area 25.78 ChemAxon refractivity 40.11 ChemAxon polarizability 16.02 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::EiMs 1809 Specdb::CMs 18199 Specdb::CMs 28913 Specdb::CMs 101834 Specdb::CMs 157347 Specdb::MsIr 7288 Specdb::MsIr 7289 Specdb::NmrOneD 4069 Specdb::NmrOneD 136550 Specdb::NmrOneD 136551 Specdb::NmrOneD 136552 Specdb::NmrOneD 136553 Specdb::NmrOneD 136554 Specdb::NmrOneD 136555 Specdb::NmrOneD 136556 Specdb::NmrOneD 136557 Specdb::NmrOneD 136558 Specdb::NmrOneD 136559 Specdb::NmrOneD 136560 Specdb::NmrOneD 136561 Specdb::NmrOneD 136562 Specdb::NmrOneD 136563 Specdb::NmrOneD 136564 Specdb::NmrOneD 136565 Specdb::NmrOneD 136566 Specdb::NmrOneD 136567 Specdb::NmrOneD 136568 Specdb::NmrOneD 136569 Specdb::MsMs 89679 Specdb::MsMs 89680 Specdb::MsMs 89681 Specdb::MsMs 152658 Specdb::MsMs 152659 Specdb::MsMs 152660 Specdb::MsMs 1476828 Specdb::MsMs 1476829 Specdb::MsMs 1476830 Specdb::MsMs 1476831 Specdb::MsMs 1476832 Specdb::MsMs 1476833 Specdb::MsMs 1476834 Specdb::MsMs 3046042 Specdb::MsMs 3046043 Specdb::MsMs 3046044 Specdb::MsMs 3094150 Specdb::MsMs 3094151 Specdb::MsMs 3094152 HMDB36584 #<Reference:0x000055ce31c4ec30> #<Reference:0x000055ce31c4e9d8> #<Reference:0x000055ce31c4e758> #<Reference:0x000055ce31c4e528> Arabica coffee Type 1 specific Coffea arabica 13443 Black tea Type 1 Breakfast cereal Type 2 specific Cereals and cereal products Unknown generic Cocoa and cocoa products Unknown generic Cocoa bean Type 1 specific Theobroma cacao 3641 Coconut Type 1 specific Cocos nucifera 13894 Coffee and coffee products Unknown generic Green bell pepper Type 1 specific Capsicum annuum 4072 Green tea Type 1 Herbal tea Type 1 Herbs and Spices Unknown generic Milk and milk products Unknown generic Nuts Unknown generic Orange bell pepper Type 1 specific Capsicum annuum 4072 Pepper Type 1 specific Capsicum annuum 4072 Potato Type 1 specific Solanum tuberosum 4113 Red bell pepper Type 1 specific Capsicum annuum 4072 Red tea Type 1 Robusta coffee Type 1 specific Coffea canephora 49390 Soy bean Type 1 specific Glycine max 3847 Tea Type 1 specific Camellia sinensis 4442 Yellow bell pepper Type 1 specific Capsicum annuum 4072 burnt chocolate cocoa coffee lard musty nutty soybean Anti anginal 114 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti bacterial 145 A substance that kills or slows the growth of bacteria. Anti cholinergic 183 Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. Anti dysmenorrheic 241 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti embolic 252 Anti histaminic 331 Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Anti hypertensive 352 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti metastatic 434 A substance that inhibits or prevents the proliferation of neoplasms. Anti thrombotic 650 Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. Anti-aggregant 94 Anti-asthmatic 134 A drug used to treat asthma. Anti-ischemic 377 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-spasmodic 619 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Arteriodilator 708 Calcium antagonist 748 Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. Cardiac 764 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Cardiotonic 771 A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. Diuretic 883 An agent that promotes the excretion of urine through its effects on kidney function. Hypotensive 1021 Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Schistosomicide 1303 Uteros sedative 1404 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Vasodilator 1413 A drug used to cause dilation of the blood vessels.