1.0 2010-04-08 22:11:54 UTC 2019-11-26 03:11:47 UTC FDB015535 Chrysin Chrysin is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea). Honeycomb also contains small amounts. It is also reported in Oroxylum indicum or Indian trumpetflower. [Wikipedia]. Chrysin is found in many foods, some of which are sour cherry, carrot, wild carrot, and sweet orange. 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one, 9CI 5,7-Dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one 5,7-Dihydroxy-2-phenylchromen-4-one 5,7-Dihydroxyflavone Chrysin Chrysinic acid Ois 3 C15H10O4 254.2375 254.057908808 5,7-dihydroxy-2-phenyl-4H-chromen-4-one chrysin 480-40-0 OC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1 InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H RTIXKCRFFJGDFG-UHFFFAOYSA-N belongs to the class of organic compounds known as flavones. These are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one). Flavones Organic compounds Phenylpropanoids and polyketides Flavonoids Flavones Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids 5-hydroxyflavonoids 7-hydroxyflavonoids Benzene and substituted derivatives Chromones Heteroaromatic compounds Hydrocarbon derivatives Organic oxides Organooxygen compounds Oxacyclic compounds Pyranones and derivatives Vinylogous acids 1-benzopyran 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid 5-hydroxyflavonoid 7-hydroxyflavonoid Aromatic heteropolycyclic compound Benzenoid Benzopyran Chromone Flavone Heteroaromatic compound Hydrocarbon derivative Hydroxyflavonoid Monocyclic benzene moiety Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Pyran Pyranone Vinylogous acid 7-hydroxyflavonol Flavones and Flavonols Flavones and Flavonols dihydroxyflavone flavones logp 3.44 ALOGPS logs -3.38 ALOGPS solubility 1.05e-01 g/l ALOGPS logp 3.01 ChemAxon pka_strongest_acidic 6.64 ChemAxon pka_strongest_basic -5.2 ChemAxon iupac 5,7-dihydroxy-2-phenyl-4H-chromen-4-one ChemAxon average_mass 254.2375 ChemAxon mono_mass 254.057908808 ChemAxon smiles OC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1 ChemAxon formula C15H10O4 ChemAxon inchi InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H ChemAxon inchikey RTIXKCRFFJGDFG-UHFFFAOYSA-N ChemAxon polar_surface_area 66.76 ChemAxon refractivity 70.93 ChemAxon polarizability 25.73 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 2120 Specdb::CMs 5871 Specdb::CMs 31656 Specdb::CMs 31997 Specdb::CMs 44934 Specdb::CMs 165805 Specdb::MsMs 10295 Specdb::MsMs 10296 Specdb::MsMs 10297 Specdb::MsMs 16967 Specdb::MsMs 16968 Specdb::MsMs 16969 Specdb::MsMs 285640 Specdb::MsMs 285641 Specdb::MsMs 285642 Specdb::MsMs 373616 Specdb::MsMs 373617 Specdb::MsMs 373618 Specdb::MsMs 374039 Specdb::MsMs 374060 Specdb::MsMs 436927 Specdb::MsMs 436928 Specdb::MsMs 436929 Specdb::MsMs 436930 Specdb::MsMs 436931 Specdb::MsMs 439472 Specdb::MsMs 439474 Specdb::MsMs 439476 Specdb::MsMs 439888 Specdb::MsMs 439889 Specdb::MsMs 439907 HMDB36619 57D #<Reference:0x000055ce302e3b88> Carrot Type 1 specific Daucus carota ssp. sativus 79200 Sour cherry Type 1 specific Prunus cerasus 140311 Sweet orange Type 1 specific Citrus sinensis 2711 0.0 0.0 0.0 mg/100 g Wild carrot Type 1 specific Daucus carota 4039 bitter Anti aflatoxin 92 A substance that diminishes the rate of a chemical reaction. Anti bacterial 145 A substance that kills or slows the growth of bacteria. Anti convulsant 204 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti estrogenic 272 A substance that diminishes the rate of a chemical reaction. Anti HIV 333 A substance that destroys or inhibits replication of viruses. Anti hypertensive 352 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti leukemic 393 A substance that inhibits or prevents the proliferation of neoplasms. Anti multidrug resistance 422 Anti proliferant 547 Anti-aggregant 94 Anti-allergic 103 A drug used to treat allergic reactions. Anti-angiogenic 115 An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. Anti-bacillary 142 A substance that kills or slows the growth of bacteria. Anti-gout 309 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-herpetic 329 A substance that destroys or inhibits replication of viruses. Anti-mutagenic 451 Anti-oxidant 502 A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. Anti-salmonella 591 A substance that kills or slows the growth of bacteria. Anti-shigellic 610 A substance that kills or slows the growth of bacteria. Anti-spasmodic 619 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-staphylococcic 627 A substance that kills or slows the growth of bacteria. Anti-stress 632 Any substance introduced into a living organism with therapeutic or diagnostic purpose. Anti-thrombic 647 Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. Anti-viral 689 A substance that destroys or inhibits replication of viruses. Antitumor 672 A substance that inhibits or prevents the proliferation of neoplasms. Anxiolytic 698 Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. Apoptotic 704 Aromatase inhibitor 705 An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones. Cancer preventive 754 A substance that inhibits or prevents the proliferation of neoplasms. Caspase-3 inhibitor 777 A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). Caspase-9 inhibitor 779 A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). Central nervous system depressant 812 A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. Cytochrome-CYP1A1 inhibitor 850 A substance that diminishes the rate of a chemical reaction. Cytotoxic 859 A role played by the molecular entity or part thereof which causes the development of a pathological process. DNA-protective 887 Estrogenic 922 Fungicide 940 A substance used to destroy fungal pests. Hepatoprotective 981 Any compound that is able to prevent damage to the liver. Hypotensive 1021 Hypouricemic 1025 ICAM-1 inhibitor 1026 A substance that diminishes the rate of a chemical reaction. JNK inhibitor 1057 A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. Monoamine-oxidase inhibitor 1089 A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. Mutagenic 1125 Myorelaxant 1134 Nitric-oxide-genic 1166 Pesticide 1210 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Radioprotective 1279 Any pharmaceutical compound containing a radioisotope. Termitifuge 1350 Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. Testosterogenic 1351 Topoisomerase-I inhibitor 1368 A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. Vasodilator 1413 A drug used to cause dilation of the blood vessels. Vasorelaxant 1417 VEGF inhibitor 1418 A substance that diminishes the rate of a chemical reaction. Xanthine oxidase inhibitor 1431 An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2).