1.0 2010-04-08 22:11:58 UTC 2025-11-19 00:56:56 UTC FDB015633 Croscarmellose Food additive. Stabiliser, thickener, moisture control agent, emulsifier. Indirect additive arising by migration from cotton fabrics used in food packaging Croscarmellose sodium also resolves formulators' concerns over long-term functional stability, reduced effectiveness at high tablet hardness levels, and similar problems associated with other products developed to enhance drug dissolution. Croscarmellose sodium is a very commonly used pharmaceutical additive approved by the U.S. Food and Drug Administration (FDA). Its purpose in most tablets - including dietary supplements - is to assist the tablet in disintegrating in the intestinal tract at the required location. If a tablet disintegrating agent is not included, the tablet could disintegrate too slowly, or in the wrong part of the intestine or not at all, thereby reducing the efficacy of the active ingredients.; Croscarmellose sodium is an internally cross-linked sodium carboxymethylcellulose for use as a disintegrant in pharmaceutical formulations. 7H (carbohydrate) Acetic acid, hydroxy-, cellulose ether Almelose Apergel Apeyel Carbose Carboximethylcellulosum Carboxymethyl cellulose Carboxymethyl cellulose ether Carboxymethylated cellulose pulp Carboxymethylcellulose Carboxymethylcellulose cellulose carboxymethyl ether Carboxymethylcellulosum Carmellose Carmellose (JP15/INN) Carmellose gum Carmellose, BAN Carmellosum Carmelosa Cellulose carboxymethylate Cellulose GUM 7H Cellulose, (carboxymethyl) Cellulose, carboxymethyl ether Cellulose, ether with glycolic acid Celluloseglycolic acid CM-cellulose CMC-4LF Colloresine Croscarmellose, BAN, INN Croscarmellosum Croscarmelosa Duodcel E466 FEMA 2239 Glycocel ta Glycolic acid cellulose ether Intrasite gel KMTS Thylose C8H16O8 240.208 240.084517475 2,3,4,5,6-pentahydroxyhexanal; acetic acid acetic acid; dextrose 9000-11-06 CC(O)=O.OCC(O)C(O)C(O)C(O)C=O InChI=1S/C6H12O6.C2H4O2/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4/h1,3-6,8-12H,2H2;1H3,(H,3,4) VJHCJDRQFCCTHL-UHFFFAOYSA-N belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity. Hexoses Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Alpha-hydroxyaldehydes Beta-hydroxy aldehydes Carboxylic acids Hydrocarbon derivatives Medium-chain aldehydes Monocarboxylic acids and derivatives Organic oxides Polyols Primary alcohols Secondary alcohols Alcohol Aldehyde Aliphatic acyclic compound Alpha-hydroxyaldehyde Beta-hydroxy aldehyde Carbonyl group Carboxylic acid Carboxylic acid derivative Hexose monosaccharide Hydrocarbon derivative Medium-chain aldehyde Monocarboxylic acid or derivatives Organic oxide Polyol Primary alcohol Secondary alcohol logp -2.41 ALOGPS logs 0.16 ALOGPS solubility 2.61e+02 g/l ALOGPS melting_point Mp 300° logp -3.6 ChemAxon pka_strongest_acidic 12.26 ChemAxon pka_strongest_basic -3 ChemAxon iupac 2,3,4,5,6-pentahydroxyhexanal; acetic acid ChemAxon average_mass 240.208 ChemAxon mono_mass 240.084517475 ChemAxon smiles CC(O)=O.OCC(O)C(O)C(O)C(O)C=O ChemAxon formula C8H16O8 ChemAxon inchi InChI=1S/C6H12O6.C2H4O2/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4/h1,3-6,8-12H,2H2;1H3,(H,3,4) ChemAxon inchikey VJHCJDRQFCCTHL-UHFFFAOYSA-N ChemAxon polar_surface_area 118.22 ChemAxon refractivity 37.35 ChemAxon polarizability 16.24 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 6 ChemAxon donor_count 5 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 50316 Specdb::MsMs 50317 Specdb::MsMs 50318 Specdb::MsMs 168438 Specdb::MsMs 168439 Specdb::MsMs 168440 odorless