1.0 2010-04-08 22:12:28 UTC 2025-11-19 01:47:30 UTC FDB016499 Kaempferide Isolated from roots of Alpinia officinarum (lesser galangal). Kaempferide is found in many foods, some of which are herbs and spices, cloves, sour cherry, and european plum. 1.3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one, 9CI 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one 3,5,7-Trihydroxy-4'-methoxy-flavone 4'-Methoxy-3,5,7-trihydroxy-flavanone 4'-Methoxy-3,5,7-trihydroxyflavone 4'-Methylkaempferol 4'-O-Methylkaempferol 5,7-Dihydroxy-4'-methoxyflavonol Campheride Flavanone, 4'-methoxy-3,5,7-trihydroxy- Flavone, 3,5,7-trihydroxy-4'-methoxy- Kaemferide Kaempferid Kaempferide Kaempferol 4'-methyl ether Kampferide Kampheride C16H12O6 300.2629 300.063388116 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one kaempferide 491-54-3 COC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 InChI=1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3 SQFSKOYWJBQGKQ-UHFFFAOYSA-N belongs to the class of organic compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. Flavonols Organic compounds Phenylpropanoids and polyketides Flavonoids Flavones Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids 3-hydroxyflavonoids 4'-O-methylated flavonoids 5-hydroxyflavonoids 7-hydroxyflavonoids Alkyl aryl ethers Anisoles Chromones Heteroaromatic compounds Hydrocarbon derivatives Methoxybenzenes Organic oxides Oxacyclic compounds Phenoxy compounds Polyols Pyranones and derivatives Vinylogous acids 1-benzopyran 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid 3-hydroxyflavone 3-hydroxyflavonoid 4p-methoxyflavonoid-skeleton 5-hydroxyflavonoid 7-hydroxyflavonoid Alkyl aryl ether Anisole Aromatic heteropolycyclic compound Benzenoid Benzopyran Chromone Ether Heteroaromatic compound Hydrocarbon derivative Hydroxyflavonoid Methoxybenzene Monocyclic benzene moiety Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Phenol ether Phenoxy compound Polyol Pyran Pyranone Vinylogous acid 7-hydroxyflavonol Flavones and Flavonols Flavones and Flavonols flavonols monomethoxyflavone trihydroxyflavone logp 2.48 ALOGPS logs -3.60 ALOGPS solubility 7.53e-02 g/l ALOGPS melting_point Mp 227-229° logp 2.61 ChemAxon pka_strongest_acidic 6.44 ChemAxon pka_strongest_basic -3.9 ChemAxon iupac 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one ChemAxon average_mass 300.2629 ChemAxon mono_mass 300.063388116 ChemAxon smiles COC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 ChemAxon formula C16H12O6 ChemAxon inchi InChI=1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3 ChemAxon inchikey SQFSKOYWJBQGKQ-UHFFFAOYSA-N ChemAxon polar_surface_area 96.22 ChemAxon refractivity 79.36 ChemAxon polarizability 29.73 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 6 ChemAxon donor_count 3 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 23635 Specdb::CMs 45388 Specdb::CMs 174507 Specdb::MsMs 102387 Specdb::MsMs 102388 Specdb::MsMs 102389 Specdb::MsMs 168198 Specdb::MsMs 168199 Specdb::MsMs 168200 Specdb::MsMs 285927 Specdb::MsMs 285928 Specdb::MsMs 285929 Specdb::MsMs 285930 Specdb::MsMs 285931 Specdb::MsMs 373731 Specdb::MsMs 373732 Specdb::MsMs 373733 Specdb::MsMs 373734 Specdb::MsMs 373735 Specdb::MsMs 373736 Specdb::MsMs 438945 Specdb::MsMs 438946 Specdb::MsMs 439137 Specdb::MsMs 439516 Specdb::MsMs 439518 Specdb::MsMs 439520 Specdb::MsMs 440240 Specdb::MsMs 440241 HMDB37441 6099 #<Reference:0x000055ce3185b830> Cloves Type 1 specific Syzygium aromaticum 219868 European plum Type 1 specific Prunus domestica 3758 Grapefruit Type 1 specific Citrus X paradisi 37656 0.0 0.0 0.0 mg/100 g Herbs and Spices Unknown generic Sour cherry Type 1 specific Prunus cerasus 140311 Anti-inflammatory 370 A substance that reduces or suppresses inflammation. Anti-mutagenic 451 Aromatase inhibitor 705 An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones. Quinone-reductase inducer 1277 Topoisomerase-I inhibitor 1368 A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA.