Record Information
Version1.0
Creation date2010-04-08 22:14:10 UTC
Update date2020-09-17 15:37:00 UTC
Primary IDFDB019141
Secondary Accession NumbersNot Available
Chemical Information
FooDB NamePhosphatidylcholine
DescriptionPC(16:0/18:1(9Z)) is a phosphatidylchloline (PC). It is a glycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. As is the case with diacylglycerols, phosphatidylcholines can have many different combinations of fatty acids of varying lengths and saturation attached to the C-1 and C-2 positions. PC(16:0/18:1(9Z)), in particular, consists of one hexadecanoyl chain to the C-1 atom, and one 9Z-octadecenoyl to the C-2 atom. In E. coli, PCs can be found in the integral component of the cell outer membrane. They are hydrolyzed by Phospholipases to a 2-acylglycerophosphocholine and a carboxylate.
CAS Number6753-55-5
Structure
Thumb
Synonyms
SynonymSource
1-16:0-2-18:1-PhosphatidylcholineChEBI
1-Hexadecanoyl-2-oleoyl-sn-glycero-3-phosphocholineChEBI
1-Palmitoyl-2-oleoyl-GPCChEBI
1-Palmitoyl-2-oleoyl-GPC (16:0/18:1)ChEBI
1-Palmitoyl-2-oleoyl-lecithinChEBI
1-Palmitoyl-2-oleoylphosphatidylcholineChEBI
1-Palmotoyl-2-oleoylglycero-3-phosphocholineChEBI
1-POPCChEBI
16:0-18:1-PCChEBI
GPC(16:0/18:1)ChEBI
GPCho(16:0/18:1)ChEBI
GPCho(16:0/18:1omega9)ChEBI
GPCho(34:1)ChEBI
LecithinChEBI
PalmitoyloleoylphosphatidylcholineChEBI
PC(16:0/18:1)ChEBI
PC(16:0/18:1omega9)ChEBI
PC(34:1)ChEBI
Phosphatidylcholine(16:0/18:1)ChEBI
Phosphatidylcholine(16:0/18:1omega9)ChEBI
Phosphatidylcholine(34:1)ChEBI
1-Palmitoyl-2-oleoylphosphatidylcholine, (R)-(Z)-isomerHMDB
POPC LipidHMDB
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholineHMDB
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholineHMDB
1-Palmitoyl-2-oleoyl-phosphatidylcholineHMDB
alpha-Phosphatidylcholine-beta-oleoyl-gamma-palmitoylHMDB
beta-Oleoyl-gamma-palmitoyl-L-alpha-phosphatidylcholineHMDB
1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineHMDB
1-Palmitoyl-2-oleoyl-3-sn-phosphatidylcholineHMDB
1-Palmitoyl-2-oleoyl-L-alpha-lecithinHMDB
1-Palmitoyl-2-oleoyl-L-alpha-phosphatidylcholineHMDB
1-Palmitoyl-2-oleoyl-L-α-lecithinHMDB
1-Palmitoyl-2-oleoyl-L-α-phosphatidylcholineHMDB
1-Palmitoyl-2-oleoyl-sn-3-phosphocholineHMDB
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphorylcholineHMDB
1-Palmitoyl-2-oleoyl-sn-glycero-phosphatidylcholineHMDB
1-Palmitoyl-2-oleoyl-sn-glycero-phosphocholineHMDB
1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphatidylcholineHMDB
1-Palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholineHMDB
1-Palmitoyl-2-oleoyl-sn-glyceryl-3-phosphorylcholineHMDB
1-Palmitoyl-2-oleoyllecithinHMDB
1-Palmitoyl-2-oleyl-3-sn-phosphatidylcholineHMDB
2-Oleo-1-palmitin phosphate choline esterHMDB
2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholineHMDB
2-Oleoyl-1-palmitoyllecithinHMDB
GPC(16:0/18:1(9Z))HMDB
GPC(16:0/18:1n9)HMDB
GPC(16:0/18:1W9)HMDB
GPC(34:1)HMDB
GPCho(16:0/18:1(9Z))HMDB
GPCho(16:0/18:1n9)HMDB
GPCho(16:0/18:1W9)HMDB
L-1-Palmitoyl-2-oleoylphosphatidylcholineHMDB
L-PalmitoyloleoylphosphatidylcholineHMDB
L-alpha-1-Palmitoyl-2-oleoylphosphatidylcholineHMDB
L-Α-1-palmitoyl-2-oleoylphosphatidylcholineHMDB
PC(16:0/18:1n9)HMDB
PC(16:0/18:1W9)HMDB
POPCHMDB
Phosphatidylcholine(16:0/18:1(9Z))HMDB
Phosphatidylcholine(16:0/18:1n9)HMDB
Phosphatidylcholine(16:0/18:1W9)HMDB
Β-oleoyl-γ-palmitoyl-L-α-phosphatidylcholineHMDB
PC(16:0/18:1(9Z))Lipid Annotator, ChEBI
1,2-Diacyl-sn-glycero-3-phosphocholinebiospider
1,2-Diacylglycero-3-phosphocholinedb_source
3-sn-Phosphatidylcholinebiospider
Choline phosphatidebiospider
Diacyllecithindb_source
Diacylphosphatidylcholinedb_source
E322db_source
Granulestindb_source
Kelecindb_source
Lecitholdb_source
Vitellindb_source
Predicted Properties
PropertyValueSource
Water Solubility2.1e-05 g/LALOGPS
logP5.59ALOGPS
logP8.64ChemAxon
logS-7.6ALOGPS
pKa (Strongest Acidic)1.86ChemAxon
pKa (Strongest Basic)-6.7ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area111.19 ŲChemAxon
Rotatable Bond Count41ChemAxon
Refractivity226.18 m³·mol⁻¹ChemAxon
Polarizability94 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Chemical FormulaC42H82NO8P
IUPAC name(2-{[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl phosphono]oxy}ethyl)trimethylazanium
InChI IdentifierInChI=1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1
InChI KeyWTJKGGKOPKCXLL-VYOBOKEXSA-N
Isomeric SMILESCCCCCCCCCCCCCCCC(=O)OC[C@]([H])(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/CCCCCCCC
Average Molecular Weight760.0761
Monoisotopic Molecular Weight759.577805117
Classification
Description belongs to the class of organic compounds known as phosphatidylcholines. These are glycerophosphocholines in which the two free -OH are attached to one fatty acid each through an ester linkage.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassGlycerophospholipids
Sub ClassGlycerophosphocholines
Direct ParentPhosphatidylcholines
Alternative Parents
Substituents
  • Diacylglycero-3-phosphocholine
  • Phosphocholine
  • Fatty acid ester
  • Dialkyl phosphate
  • Dicarboxylic acid or derivatives
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Alkyl phosphate
  • Fatty acyl
  • Quaternary ammonium salt
  • Tetraalkylammonium salt
  • Carboxylic acid ester
  • Carboxylic acid derivative
  • Organic oxygen compound
  • Organic nitrogen compound
  • Carbonyl group
  • Organooxygen compound
  • Organonitrogen compound
  • Organic oxide
  • Organopnictogen compound
  • Amine
  • Organic salt
  • Hydrocarbon derivative
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Ontology
OntologyNo ontology term
Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateNot Available
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
Spectrum TypeDescriptionSplash KeyView
LC-MS/MSLC-MS/MS Spectrum - QqQ 1V, negativesplash10-000t-0090200800-c8db3c4042d858672ebdJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - IT 40V, negativesplash10-0006-0020000900-603012fb0ce5ff46f1eaJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 24V, negativesplash10-0udi-0000000190-afc4cd2ac0e64fa39623JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 30V, negativesplash10-0udl-0000000490-09171592a6955e57e163JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 36V, negativesplash10-0f6x-0000000940-3b9edba3cc0cdfff4945JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 42V, negativesplash10-0006-0030000910-e80b4b8f6690eea16c9dJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 48V, negativesplash10-000x-0090000700-527aadfe756a5f2ad9a5JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 54V, negativesplash10-053r-0090000200-e27632edecd3a83538a4JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 60V, negativesplash10-053r-0090000000-875a5d38cc2b636df4a1JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 72V, negativesplash10-053r-0090000000-6bdad7ea857755dad8dfJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 91V, negativesplash10-053r-0090000000-a0160ca0a20b8ca408deJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 109V, negativesplash10-053r-0090000000-d2bc446076d9d86bbadfJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 133V, negativesplash10-053r-1090000000-a94d8052959d35d3d25eJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 157V, negativesplash10-057i-5190000000-12de950663c450d5ad7fJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 194V, negativesplash10-004i-9000000000-906a0ebc0dd0220ac288JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - n/a 53V, negativesplash10-0006-0000000900-0bfd0ce87b7b119d82fbJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 22V, negativesplash10-0006-0000000900-88f30608c9fd0df934c2JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 28V, negativesplash10-0006-0000000900-fb159b53855796db7d35JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 34V, negativesplash10-0006-0000000900-084480cec1d6930fa834JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 41V, negativesplash10-0006-0020000900-103adeac53f876868122JSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 47V, negativesplash10-000x-0090000800-a9198efdf2f4fe5ec5daJSpectraViewer | MoNA
LC-MS/MSLC-MS/MS Spectrum - Orbitrap 53V, negativesplash10-053r-0090000200-9df170809bae304c6bc1JSpectraViewer | MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-0000000900-64875131a83d4fda43e6JSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03e9-0600000900-dfb450caf9537c97446eJSpectraViewer
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0fai-1900230300-31ec54e207b217422a2eJSpectraViewer
ChemSpider IDNot Available
ChEMBL IDNot Available
KEGG Compound IDC00157
Pubchem Compound IDNot Available
Pubchem Substance ID3457
ChEBI ID49183
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDNot Available
CRC / DFC (Dictionary of Food Compounds) IDLRV43-T:LRV43-T
EAFUS ID2000
Dr. Duke IDLECITHIN|PHOSPHATIDYL-CHOLINE
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDrw1099111
SuperScent IDNot Available
Wikipedia IDPhosphatidylcholine
Phenol-Explorer Metabolite IDNot Available
Duplicate IDS
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / Bioactivities
DescriptorIDDefinitionReference
anti Alzheimeran52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
anti ataxicDUKE
anti cirrhotic52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
anti dementia52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
anti dyskineticDUKE
anti eczemic52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
anti lithicDUKE
anti manicDUKE
anti morphinisticDUKE
antioxidant22586 A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324.DUKE
anti psoriac52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
anti sclerodermic50177 A drug used to treat or prevent skin disorders or for the routine care of skin.DUKE
anti seborrheic52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
anti sprueDUKE
anti Tourette's52217 Any substance introduced into a living organism with therapeutic or diagnostic purpose.DUKE
antitumor35610 A substance that inhibits or prevents the proliferation of neoplasms.DUKE
cholinergic38323 Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.DUKE
hepatoprotective62868 Any compound that is able to prevent damage to the liver.DUKE
hypocholesterolemicDUKE
lipotropicDUKE
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
Flavours
FlavorCitations
bland
  1. The Good Scents Company (2009). Flavor and fragrance information catalog. <http://www.thegoodscentscompany.com/allprod.html> Accessed 15.10.23.
Files
MSDSNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference— Duke, James. 'Dr. Duke's Phytochemical and Ethnobotanical Databases. United States Department of Agriculture.' Agricultural Research Service, Accessed April 27 (2004).