1.0 2011-03-17 23:27:38 UTC 2025-11-19 02:39:13 UTC FDB021711 6,7-Dimethylscutellarein Scutellarein, also known as 6-hydroxyapigenin or 4',5,6,7-tetrahydroxyflavanone, is a member of the class of compounds known as flavones. Flavones are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one). Thus, scutellarein is considered to be a flavonoid lipid molecule. Scutellarein is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Scutellarein can be synthesized from apigenin. Scutellarein is also a parent compound for other transformation products, including but not limited to, scutellarin, 4',6-dihydroxy-5,7-dimethoxyflavone, and 6-hydroxy-4',5,7-trimethoxyflavone. Scutellarein is a bitter tasting compound found in mexican oregano and sweet orange, which makes scutellarein a potential biomarker for the consumption of these food products. Scutellarein is a flavone that can be found in Scutellaria lateriflora and other members of the genus Scutellaria, as well as the fern Asplenium belangeri . 6,7-Dimethoxy-4',5-dihydroxyflavone 6,7-Dimethylscutellarein C15H10O6 286.2363 286.047738052 5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one scutellarein 529-53-3 OC1=CC=C(C=C1)C1=CC(=O)C2=C(O1)C=C(O)C(O)=C2O InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H JVXZRQGOGOXCEC-UHFFFAOYSA-N belongs to the class of organic compounds known as flavones. These are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one). Flavones Organic compounds Phenylpropanoids and polyketides Flavonoids Flavones Aromatic heteropolycyclic compounds 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids 4'-hydroxyflavonoids 5-hydroxyflavonoids 6-hydroxyflavonoids 7-hydroxyflavonoids Benzene and substituted derivatives Chromones Heteroaromatic compounds Hydrocarbon derivatives Organic oxides Oxacyclic compounds Polyols Pyranones and derivatives Vinylogous acids 1-benzopyran 1-hydroxy-2-unsubstituted benzenoid 1-hydroxy-4-unsubstituted benzenoid 4'-hydroxyflavonoid 5-hydroxyflavonoid 6-hydroxyflavonoid 7-hydroxyflavonoid Aromatic heteropolycyclic compound Benzenoid Benzopyran Chromone Flavone Heteroaromatic compound Hydrocarbon derivative Hydroxyflavonoid Monocyclic benzene moiety Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Phenol Polyol Pyran Pyranone Vinylogous acid Flavones and Flavonols a flavone flavanones flavones tetrahydroxyflavone logp 2.74 ALOGPS logs -3.26 ALOGPS solubility 1.56e-01 g/l ALOGPS logp 2.4 ChemAxon pka_strongest_acidic 6.75 ChemAxon pka_strongest_basic -5.4 ChemAxon iupac 5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one ChemAxon average_mass 286.2363 ChemAxon mono_mass 286.047738052 ChemAxon smiles OC1=CC=C(C=C1)C1=CC(=O)C2=C(O1)C=C(O)C(O)=C2O ChemAxon formula C15H10O6 ChemAxon inchi InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H ChemAxon inchikey JVXZRQGOGOXCEC-UHFFFAOYSA-N ChemAxon polar_surface_area 107.22 ChemAxon refractivity 74.89 ChemAxon polarizability 27.73 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 5833 Specdb::CMs 52986 Specdb::CMs 166168 Specdb::MsMs 62064 Specdb::MsMs 62065 Specdb::MsMs 62066 Specdb::MsMs 118722 Specdb::MsMs 118723 Specdb::MsMs 118724 Specdb::MsMs 285722 Specdb::MsMs 285723 Specdb::MsMs 285724 Specdb::MsMs 285725 Specdb::MsMs 285726 Specdb::MsMs 2450770 Specdb::MsMs 2450771 Specdb::MsMs 2450772 Specdb::MsMs 2488644 Specdb::MsMs 2488645 Specdb::MsMs 2488646 Winter savory Type 1 specific Satureja montana 49988