Showing Compound ADP (FDB021817)

Record Information

Version

1.0

Creation date

2011-04-11 17:01:45 UTC

Update date

2025-11-19 02:39:48 UTC

Primary ID

FDB021817

Secondary Accession Numbers

Not Available

Chemical Information

FooDB Name

ADP

Description

[(2S,3R,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate belongs to the class of organic compounds known as purine ribonucleoside diphosphates. These are purine ribobucleotides with diphosphate group linked to the ribose moiety. [(2S,3R,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate is found, on average, in the highest concentration within milk (cow) and beer. [(2S,3R,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate has also been detected, but not quantified in, several different foods, such as watercresses (Rorippa nasturtium-aquaticum), common cabbages (Brassica oleracea), tree ferns (Cyathea), black elderberries (Sambucus nigra), and lingonberries (Vaccinium vitis-idaea). This could make [(2S,3R,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate a potential biomarker for the consumption of these foods. Based on a literature review very few articles have been published on [(2S,3R,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate.

CAS Number

58-64-0

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
[(2S,3R,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphoric acid	Generator
5'-Adenyloric acid	ChEBI
Adenosindiorsaeure	HMDB
Adenosine 5'-diate	ChEBI
Adenosine 5'-diic acid	Generator
Adenosine 5'-pyroate	HMDB
Adenosine diate	HMDB
Adenosine pyroate	HMDB
Adenosine-5-diate	HMDB
ADENOSINE-5'-diATE	ChEBI
ADENOSINE-5'-diic acid	Generator
Adenosine-diate	HMDB
H3ADP	ChEBI

Predicted Properties

Property	Value	Source
Water Solubility	3.27 g/L	ALOGPS
logP	-1.6	ALOGPS
logP	-4.7	ChemAxon
logS	-2.1	ALOGPS
pKa (Strongest Acidic)	1.77	ChemAxon
pKa (Strongest Basic)	4	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	12	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	232.6 Å²	ChemAxon
Rotatable Bond Count	6	ChemAxon
Refractivity	84.94 m³·mol⁻¹	ChemAxon
Polarizability	34.82 Å³	ChemAxon
Number of Rings	3	ChemAxon
Bioavailability	No	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	Yes	ChemAxon

Chemical Formula

C10H15N5O10P2

IUPAC name

[({[5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid

InChI Identifier

InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)

InChI Key

XTWYTFMLZFPYCI-UHFFFAOYSA-N

Isomeric SMILES

NC1=C2N=CN(C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O)C2=NC=N1

Average Molecular Weight

427.2011

Monoisotopic Molecular Weight

427.029414749

Classification

Description

Belongs to the class of organic compounds known as purine ribonucleoside diphosphates. These are purine ribobucleotides with diphosphate group linked to the ribose moiety.

Kingdom

Organic compounds

Super Class

Nucleosides, nucleotides, and analogues

Class

Purine nucleotides

Sub Class

Purine ribonucleotides

Direct Parent

Purine ribonucleoside diphosphates

Alternative Parents

Substituents

Purine ribonucleoside diphosphate
Purine ribonucleoside monophosphate
Pentose phosphate
Pentose-5-phosphate
Glycosyl compound
N-glycosyl compound
6-aminopurine
Monosaccharide phosphate
Organic pyrophosphate
Pentose monosaccharide
Imidazopyrimidine
Purine
Monoalkyl phosphate
Aminopyrimidine
Alkyl phosphate
Monosaccharide
N-substituted imidazole
Organic phosphoric acid derivative
Phosphoric acid ester
Imidolactam
Pyrimidine
Azole
Heteroaromatic compound
Imidazole
Tetrahydrofuran
Secondary alcohol
1,2-diol
Azacycle
Oxacycle
Organoheterocyclic compound
Alcohol
Organonitrogen compound
Organic oxide
Organic nitrogen compound
Organooxygen compound
Organopnictogen compound
Organic oxygen compound
Primary amine
Amine
Hydrocarbon derivative
Aromatic heteropolycyclic compound

Molecular Framework

Aromatic heteropolycyclic compounds

External Descriptors

Not Available

Ontology

No ontology term

Physico-Chemical Properties

Physico-Chemical Properties - Experimental

Property	Value	Reference
Physical state	Solid
Physical Description	Not Available
Mass Composition	Not Available
Melting Point	Not Available
Boiling Point	Not Available
Experimental Water Solubility	Not Available
Experimental logP	Not Available
Experimental pKa	Not Available
Isoelectric point	Not Available
Charge	Not Available
Optical Rotation	Not Available
Spectroscopic UV Data	Not Available
Density	Not Available
Refractive Index	Not Available

Spectra

EI-MS/GC-MS

Type	Description	Splash Key	View
Predicted GC-MS	ADP, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	splash10-004i-5931200000-25d0f5b9843a9beec982	Spectrum
Predicted GC-MS	ADP, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_1_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_1_4, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_1_5, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_4, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_5, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_6, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_7, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_8, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_9, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_10, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_11, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TMS_2_12, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TBDMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TBDMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TBDMS_1_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TBDMS_1_4, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TBDMS_1_5, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ADP, TBDMS_2_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum

MS/MS

Type	Description	Splash Key	View
MS/MS	LC-MS/MS Spectrum - 40V, Positive	splash10-000i-0900000000-ff8da8678dc27f90601c	2021-09-20	View Spectrum
MS/MS	LC-MS/MS Spectrum - 30V, Positive	splash10-000i-0900000000-ecf85c04f4d3073fc384	2021-09-20	View Spectrum
MS/MS	LC-MS/MS Spectrum - 10V, Positive	splash10-004i-0000900000-f0519b6103ee3cc8f220	2021-09-20	View Spectrum
MS/MS	LC-MS/MS Spectrum - 20V, Positive	splash10-000i-0902000000-4f02617024a085376b03	2021-09-20	View Spectrum
MS/MS	LC-MS/MS Spectrum - 50V, Positive	splash10-000i-0900000000-a7c425a5fc3acd4407fc	2021-09-20	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-000i-0911300000-8da046fe4e4b22cb87ff	2018-04-05	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-000i-1900000000-fb70ac7c7b9b55c6fcae	2018-04-05	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-000i-1900000000-4e108f56e1fc69b49d20	2018-04-05	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0059-0900800000-ce4dd0640834d00c4476	2018-04-06	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-003r-6900000000-6ad0a45e42f378f13c6b	2018-04-06	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-004i-9200000000-954c0cab31cbfa0afc8d	2018-04-06	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-004i-0200900000-37930c002988c01e9afd	2021-10-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-000i-0910000000-bde23cc2780695c7390d	2021-10-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0079-1950000000-84d8ec4e1358b4a1c80c	2021-10-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-004i-0001900000-840b6d02b69b9a766654	2021-10-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-004i-9201200000-7445f0a2e044d0063ef6	2021-10-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-004i-9100000000-c2cd0a0ac756ee6430ef	2021-10-12	View Spectrum

NMR

Not Available

External Links

ChemSpider ID

ChEMBL ID

KEGG Compound ID

Pubchem Compound ID

Pubchem Substance ID

Not Available

ChEBI ID

Not Available

Phenol-Explorer ID

Not Available

DrugBank ID

Not Available

HMDB ID

HMDB01341

CRC / DFC (Dictionary of Food Compounds) ID

HJD92-Z:HJD92-Z

EAFUS ID

Not Available

Dr. Duke ID

Not Available

BIGG ID

33496

KNApSAcK ID

Not Available

HET ID

ADP

Food Biomarker Ontology

Not Available

VMH ID

Not Available

Flavornet ID

Not Available

GoodScent ID

Not Available

SuperScent ID

Not Available

Wikipedia ID

Adenosine diphosphate

Phenol-Explorer Metabolite ID

Not Available

Duplicate IDS

Not Available

Old DFC IDS

Not Available

Associated Foods

Food	Content Range	Average	Reference
Food			Reference

Biological Effects and Interactions

Health Effects / Bioactivities

Not Available

Enzymes

Name	Gene Name	UniProt ID
Sedoheptulokinase	SHPK	Q9UHJ6
Inositol-pentakisphosphate 2-kinase	IPPK	Q9H8X2
Inositol hexakisphosphate kinase 3	IHPK3	Q5TAQ4
Putative uncharacterized protein IP6K1	IP6K1	Q92551
Epidermal growth factor receptor	EGFR	P00533
Propionyl-CoA carboxylase beta chain, mitochondrial	PCCB	P05166
Trifunctional purine biosynthetic protein adenosine-3	GART	P22102
Glutathione synthetase	GSS	P48637
Glutamate--cysteine ligase catalytic subunit	GCLC	P48506
Choline/ethanolamine kinase	CHKB	Q9Y259
Choline kinase alpha	CHKA	P35790
Serum paraoxonase/lactonase 3	PON3	Q15166
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1	PAPSS1	O43252
Glycerol kinase 2	GK2	Q14410
Glycerol kinase	GK	P32189
Putative glycerol kinase 3	GK3P	Q14409
Putative glycerol kinase 5	GK5	Q6ZS86
Ethanolamine kinase 1	ETNK1	Q9HBU6
Ethanolamine kinase 2	ETNK2	Q9NVF9
V-type proton ATPase catalytic subunit A	ATP6V1A	P38606
V-type proton ATPase subunit C 1	ATP6V1C1	P21283
N-acetylgalactosamine kinase	GALK2	Q01415
Galactokinase	GALK1	P51570
Glucokinase	GCK	P35557
Hexokinase-3	HK3	P52790
Hexokinase-2	HK2	P52789
Hexokinase-1	HK1	P19367
Insulin-like growth factor 1 receptor	IGF1R	P08069
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	GNE	Q9Y223
ATP-citrate synthase	ACLY	P53396
Deoxycytidine kinase	DCK	P27707
Probable gluconokinase	IDNK	Q5T6J7
[Protein ADP-ribosylarginine] hydrolase	ADPRH	P54922
Homeodomain-interacting protein kinase 1	HIPK1	Q86Z02
Proto-oncogene tyrosine-protein kinase Src	SRC	P12931
Inositol-trisphosphate 3-kinase A	ITPKA	P23677
Myosin light chain kinase 2, skeletal/cardiac muscle	MYLK2	Q9H1R3
Calcium/calmodulin-dependent protein kinase type II subunit delta	CAMK2D	Q13557
Calcium/calmodulin-dependent protein kinase ID	CAMK1D	Q5SQQ7
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta	CAMK2B	A4D2J9
Putative uncharacterized protein DKFZp686I0955	DKFZp686I0955	Q5HYC3
Calcium/calmodulin-dependent protein kinase I, isoform CRA_a	CAMK1	B0YIY3
Sodium/potassium-transporting ATPase subunit beta-3	ATP1B3	P54709
Sodium/potassium-transporting ATPase subunit beta-2	ATP1B2	P14415
Potassium-transporting ATPase alpha chain 2	ATP12A	P54707
Potassium-transporting ATPase subunit beta	ATP4B	P51164
Potassium-transporting ATPase alpha chain 1	ATP4A	P20648
Delta-1-pyrroline-5-carboxylate synthase	ALDH18A1	P54886
Beta-adrenergic receptor kinase 1	ADRBK1	P25098
Beta-adrenergic receptor kinase 2	ADRBK2	P35626
Rhodopsin kinase	GRK1	Q15835
G protein-coupled receptor kinase 7	GRK7	Q8WTQ7
Carbamoyl-phosphate synthase [ammonia], mitochondrial	CPS1	P31327
Glutamine synthetase	GLUL	P15104
CTP synthase 2	CTPS2	Q9NRF8
Glycogen synthase kinase-3 beta	GSK3B	P49841
Ketohexokinase	KHK	P50053
Mevalonate kinase	MVK	Q03426
Creatine kinase S-type, mitochondrial	CKMT2	P17540
Creatine kinase B-type	CKB	P12277
Creatine kinase U-type, mitochondrial	CKMT1A	P12532
Creatine kinase M-type	CKM	P06732
Uridine-cytidine kinase-like 1	UCKL1	Q9NWZ5
UMP-CMP kinase 2, mitochondrial	CMPK2	Q5EBM0
Ribonucleoside-diphosphate reductase large subunit	RRM1	P23921
GTP:AMP phosphotransferase, mitochondrial	AK3	Q9UIJ7
Polyribonucleotide nucleotidyltransferase 1, mitochondrial	PNPT1	Q8TCS8
N-acetyl-D-glucosamine kinase	NAGK	Q9UJ70
Spliceosome RNA helicase DDX39B	DDX39B	Q13838
Thiamin pyrophosphokinase 1	TPK1	Q9H3S4
Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)	DAK	Q3LXA3
Ribokinase	RBKS	Q9H477
Pantothenate kinase 4	PANK4	Q9NVE7
Pantothenate kinase 1	PANK1	Q8TE04
Pantothenate kinase 3	PANK3	Q9H999
Propionyl-CoA carboxylase alpha chain, mitochondrial	PCCA	P05165
Deoxyguanosine kinase, mitochondrial	DGUOK	Q16854
Phosphoribosylformylglycinamidine synthase	PFAS	O15067
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial	PET112	O75879
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial	QRSL1	Q9H0R6
Glycerate kinase	GLYCTK	Q8IVS8
Adenylate kinase 2, mitochondrial	AK2	P54819
Guanylate kinase	GUK1	Q16774
Folylpolyglutamate synthase, mitochondrial	FPGS	Q05932
5-oxoprolinase	OPLAH	O14841
Multifunctional protein ADE2	PAICS	P22234
Thymidine kinase, cytosolic	TK1	P04183
Thymidine kinase 2, mitochondrial	TK2	O00142
C-1-tetrahydrofolate synthase, cytoplasmic	MTHFD1	P11586
Monofunctional C1-tetrahydrofolate synthase, mitochondrial	MTHFD1L	Q6UB35
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	MTHFD2	Q7Z650
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2	PAPSS2	O95340
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	MCCC2	Q9HCC0
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial	MCCC1	Q96RQ3
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	PFKFB3	Q16875
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4	PFKFB4	Q16877
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1	PFKFB1	P16118
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2	PFKFB2	O60825
Diphosphomevalonate decarboxylase	MVD	P53602
Katanin p60 ATPase-containing subunit A1	KATNA1	O75449
Bifunctional polynucleotide phosphatase/kinase	PNKP	Q96T60
Bifunctional coenzyme A synthase	COASY	Q13057
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial	HIBCH	Q6NVY1
RuvB-like 2	RUVBL2	Q9Y230
Cancer-related nucleoside-triphosphatase	NTPCR	Q9BSD7
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16	DHX16	O60231
V-type proton ATPase subunit G 3	ATP6V1G3	Q96LB4
V-type proton ATPase subunit G 1	ATP6V1G1	O75348
ATP synthase subunit epsilon, mitochondrial	ATP5E	P56381
ATP synthase subunit delta, mitochondrial	ATP5D	P30049
V-type proton ATPase subunit G 2	ATP6V1G2	O95670
ATP synthase subunit O, mitochondrial	ATP5O	P48047
ATP synthase-coupling factor 6, mitochondrial	ATP5J	P18859
ATP synthase protein 8	MT-ATP8	P03928
ATP synthase subunit e, mitochondrial	ATP5I	P56385
ATP synthase subunit gamma, mitochondrial	ATP5C1	P36542
V-type proton ATPase subunit d 1	ATP6V0D1	P61421
V-type proton ATPase subunit B, brain isoform	ATP6V1B2	P21281
ATP synthase subunit b, mitochondrial	ATP5F1	P24539
ATP synthase subunit alpha, mitochondrial	ATP5A1	P25705
Probable phospholipid-transporting ATPase IIB	ATP9B	O43861
V-type proton ATPase 16 kDa proteolipid subunit	ATP6V0C	P27449
V-type proton ATPase subunit e 1	ATP6V0E1	O15342
ATP synthase subunit d, mitochondrial	ATP5H	O75947
ATP synthase subunit f, mitochondrial	ATP5J2	P56134
V-type proton ATPase 116 kDa subunit a isoform 2	ATP6V0A2	Q9Y487
ATP synthase lipid-binding protein, mitochondrial	ATP5G3	P48201
V-type proton ATPase subunit H	ATP6V1H	Q9UI12
V-type proton ATPase subunit D	ATP6V1D	Q9Y5K8
V-type proton ATPase subunit d 2	ATP6V0D2	Q8N8Y2
V-ATPase subunit E 2	ATP6V1E2	Q96A05
V-type proton ATPase subunit C 2	ATP6V1C2	Q8NEY4
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 (T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3, isoform CRA_c)	TCIRG1	Q13488
V-type proton ATPase subunit e 2	ATP6V0E2	Q8NHE4
Putative uncharacterized protein ATP6V1E1	ATP6V1E1	P36543
ATPase, H+ transporting, lysosomal accessory protein 1 (ATPase, H+ transporting, lysosomal accessory protein 1, isoform CRA_d) (cDNA FLJ78461, highly similar to Homo sapiens ATPase, H+ transporting, lysosomal accessory protein 1 (ATP6AP1), mRNA) (Fragment	ATP6AP1	Q15904
ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	ATP6V1F	A4D1K0
Cell division protein kinase 5	CDK5	Q00535
L-fucose kinase	FUK	Q8N0W3
Adenylate kinase isoenzyme 1	AK1	P00568
Adenylate kinase isoenzyme 4, mitochondrial	AK4	P27144
Adenylate kinase 7	AK7	Q96M32
Thymidylate kinase	DTYMK	P23919
Phosphomevalonate kinase	PMVK	Q15126
cGMP-dependent protein kinase 1	PRKG1	Q13976
cGMP-dependent protein kinase 2	PRKG2	Q13237
Serine/threonine-protein kinase RIO2	RIOK2	Q9BVS4
Cell division protein kinase 3	CDK3	Q00526
Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma	PIK3C2G	O75747
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform	PIK3CD	O00329
Tyrosine-protein kinase TXK	TXK	P42681
Epithelial discoidin domain-containing receptor 1	DDR1	Q08345
Receptor-interacting serine/threonine-protein kinase 3	RIPK3	Q9Y572
BDNF/NT-3 growth factors receptor	NTRK2	Q16620
Myosin-IIIa	MYO3A	Q8NEV4
Macrophage-stimulating protein receptor	MST1R	Q04912
Vascular endothelial growth factor receptor 3	FLT4	P35916
Dual specificity protein kinase CLK4	CLK4	Q9HAZ1
Receptor tyrosine-protein kinase erbB-3	ERBB3	P21860
Ephrin type-A receptor 5	EPHA5	P54756
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial	PDK1	Q15118
Cell division protein kinase 10	CDK10	Q15131
Mitogen-activated protein kinase kinase kinase 14	MAP3K14	Q99558
Tyrosine-protein kinase transmembrane receptor ROR2	ROR2	Q01974
MAP/microtubule affinity-regulating kinase 3	MARK3	P27448
Tyrosine-protein kinase-like 7	PTK7	Q13308
Mitotic checkpoint serine/threonine-protein kinase BUB1	BUB1	O43683
Ephrin type-B receptor 1	EPHB1	P54762
FL cytokine receptor	FLT3	P36888
Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform	PHKG1	Q16816
Tyrosine-protein kinase JAK2	JAK2	O60674
Serine/threonine-protein kinase N2	PKN2	Q16513
Maternal embryonic leucine zipper kinase	MELK	Q14680
Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha	PIP4K2A	P48426
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform	PIK3CB	P42338
Cyclin-dependent kinase-like 5	CDKL5	O76039
Cell division protein kinase 17	CDK17	Q00537
Protein-tyrosine kinase 6	PTK6	Q13882
Tyrosine-protein kinase receptor TYRO3	TYRO3	Q06418
ALK tyrosine kinase receptor	ALK	Q9UM73
Proto-oncogene tyrosine-protein kinase Yes	YES1	P07947
Serine-protein kinase ATM	ATM	Q13315
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	DYRK1B	Q9Y463
Fibroblast growth factor receptor 4	FGFR4	P22455
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	PIK3CA	P42336
Serine/threonine-protein kinase pim-3	PIM3	Q86V86
Hormonally up-regulated neu tumor-associated kinase	HUNK	P57058
MAP/microtubule affinity-regulating kinase 4	MARK4	Q96L34
Insulin receptor-related protein	INSRR	P14616
Ephrin type-A receptor 2	EPHA2	P29317
Dual specificity protein kinase CLK1	CLK1	P49759
Tyrosine-protein kinase HCK	HCK	P08631
Homeodomain-interacting protein kinase 3	HIPK3	Q9H422
Discoidin domain-containing receptor 2	DDR2	Q16832
Serine/threonine-protein kinase 10	STK10	O94804
Cell division protein kinase 13	CDK13	Q14004
Serine/threonine-protein kinase VRK1	VRK1	Q99986
Vascular endothelial growth factor receptor 2	KDR	P35968
Serine/threonine-protein kinase pim-2	PIM2	Q9P1W9
Focal adhesion kinase 1	PTK2	Q05397
Serine/threonine-protein kinase 35	STK35	Q8TDR2
Inositol polyphosphate multikinase	IPMK	Q8NFU5
Serine/threonine-protein kinase PRP4 homolog	PRPF4B	Q13523
Serine/threonine-protein kinase PLK4	PLK4	O00444
Non-receptor tyrosine-protein kinase TNK1	TNK1	Q13470
Cell division protein kinase 12	CDK12	Q9NYV4
Ephrin type-B receptor 4	EPHB4	P54760
Dual specificity protein kinase CLK2	CLK2	P49760
Inhibitor of nuclear factor kappa-B kinase subunit beta	IKBKB	O14920
Fibroblast growth factor receptor 2	FGFR2	P21802
Tyrosine-protein kinase JAK1	JAK1	P23458
Macrophage colony-stimulating factor 1 receptor	CSF1R	P07333
Serine/threonine-protein kinase 6	AURKA	O14965
Proto-oncogene serine/threonine-protein kinase mos	MOS	P00540
RAC-beta serine/threonine-protein kinase	AKT2	P31751
Serine/threonine-protein kinase VRK2	VRK2	Q86Y07
DNA-dependent protein kinase catalytic subunit	PRKDC	P78527
Ephrin type-A receptor 7	EPHA7	Q15375
Serine/threonine-protein kinase ULK1	ULK1	O75385
Tyrosine-protein kinase Mer	MERTK	Q12866
Serine/threonine-protein kinase Sgk2	SGK2	Q9HBY8
TP53-regulating kinase	TP53RK	Q96S44
Serine/threonine-protein kinase MAK	MAK	P20794
Ephrin type-A receptor 1	EPHA1	P21709
Phosphatidylinositol-5-phosphate 4-kinase type-2 beta	PIP4K2B	P78356
Alpha-type platelet-derived growth factor receptor	PDGFRA	P16234
Tyrosine-protein kinase Lck	LCK	P06239
Tyrosine-protein kinase JAK3	JAK3	P52333
Cell division protein kinase 9	CDK9	P50750
Muscle, skeletal receptor tyrosine-protein kinase	MUSK	O15146
Fibroblast growth factor receptor 3	FGFR3	P22607
RAC-gamma serine/threonine-protein kinase	AKT3	Q9Y243
Dual specificity mitogen-activated protein kinase kinase 4	MAP2K4	P45985
Ephrin type-A receptor 3	EPHA3	P29320
Non-receptor tyrosine-protein kinase TYK2	TYK2	P29597
Receptor tyrosine-protein kinase erbB-4	ERBB4	Q15303
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	PKMYT1	Q99640
Glycogen synthase kinase-3 alpha	GSK3A	P49840
Cell division protein kinase 7	CDK7	P50613
Tyrosine-protein kinase Fgr	FGR	P09769
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PIK3CG	P48736
Phosphorylase b kinase gamma catalytic chain, testis/liver isoform	PHKG2	P15735
Cell division protein kinase 4	CDK4	P11802
Phosphatidylinositol 4-kinase alpha	PI4KA	P42356
Serine/threonine-protein kinase RIO1	RIOK1	Q9BRS2
Serine/threonine-protein kinase 16	STK16	O75716
Ribosomal protein S6 kinase beta-1	RPS6KB1	P23443
Ephrin type-A receptor 4	EPHA4	P54764
3-phosphoinositide-dependent protein kinase 1	PDPK1	O15530
STE20/SPS1-related proline-alanine-rich protein kinase	STK39	Q9UEW8
Casein kinase II subunit alpha	CSNK2A1	P68400
Serine/threonine-protein kinase PLK2	PLK2	Q9NYY3
Beta-type platelet-derived growth factor receptor	PDGFRB	P09619
Tyrosine-protein kinase Blk	BLK	P51451
Cyclin-dependent kinase-like 1	CDKL1	Q00532
Tyrosine-protein kinase receptor Tie-1	TIE1	P35590
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	BUB1B	O60566
Tyrosine-protein kinase RYK	RYK	P34925
Integrin-linked protein kinase	ILK	Q13418
Vascular endothelial growth factor receptor 1	FLT1	P17948
Receptor tyrosine-protein kinase erbB-2	ERBB2	P04626
Serine/threonine-protein kinase Chk1	CHEK1	O14757
Casein kinase II subunit alpha'	CSNK2A2	P19784
Tyrosine-protein kinase FRK	FRK	P42685
Proto-oncogene tyrosine-protein kinase ROS	ROS1	P08922
Cell division protein kinase 19	CDK19	Q9BWU1
Cell division protein kinase 18	CDK18	Q07002
Tyrosine-protein kinase Fes/Fps	FES	P07332
Tyrosine-protein kinase Fer	FER	P16591
Tyrosine-protein kinase STYK1	STYK1	Q6J9G0
Phosphoglycerate kinase 2	PGK2	P07205
Receptor-interacting serine/threonine-protein kinase 2	RIPK2	O43353
Ephrin type-B receptor 3	EPHB3	P54753
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial	PDK3	Q15120
Tyrosine-protein kinase Srms	SRMS	Q9H3Y6
Mast/stem cell growth factor receptor	KIT	P10721
Serine/threonine-protein kinase PLK1	PLK1	P53350
Tyrosine-protein kinase ZAP-70	ZAP70	P43403
Serine/threonine-protein kinase 17B	STK17B	O94768
Insulin receptor	INSR	P06213
Serine/threonine-protein kinase DCLK2	DCLK2	Q8N568
Proto-oncogene tyrosine-protein kinase receptor Ret	RET	P07949
Phosphoglycerate kinase 1	PGK1	P00558
Serine/threonine-protein kinase 17A	STK17A	Q9UEE5
Serine/threonine-protein kinase N1	PKN1	Q16512
Ephrin type-B receptor 2	EPHB2	P29323
Serine/threonine-protein kinase H1	PSKH1	P11801
Inhibitor of nuclear factor kappa-B kinase subunit alpha	CHUK	O15111
Xylulose kinase	XYLB	O75191
Dual specificity mitogen-activated protein kinase kinase 3	MAP2K3	P46734
MAP kinase-activated protein kinase 2	MAPKAPK2	P49137
Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma	PIP5K1C	O60331
Phosphatidylinositol 4-kinase, catalytic, beta polypeptide	PIK4CB	Q9UBF8
Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma	PIP4K2C	Q8TBX8
Sphingosine kinase 1	SPHK1	Q96GK1
Diacylglycerol kinase, epsilon 64kDa	DGKE	A1L4Q0
Multiple substrate lipid kinase, isoform CRA_a	FLJ10842	A4D1U5
Phosphoinositide-3-kinase, class 2, beta polypeptide	PIK3C2B	A2RUF7
EPH receptor A8	EPHA8	P29322
Ephrin type-B receptor 6	EPHB6	O15197
Ephrin type-A receptor 10	EPHA10	Q5JZY3
Met proto-oncogene (Hepatocyte growth factor receptor)	MET	P08581
Neurotrophic tyrosine kinase, receptor, type 3	NTRK3	Q96CY4
ROR1 protein	ROR1	Q01973
AXL receptor tyrosine kinase	AXL	P30530
LYN protein	LYN	Q6NUK7
Leucine-rich repeat serine/threonine-protein kinase 2	LRRK2	Q5S007
Myosin-IIIb	MYO3B	Q8WXR4
CSNK1A1 protein	CSNK1A1	Q6PJ06
Casein kinase I isoform delta	CSNK1D	P48730
Casein kinase I isoform epsilon	CSNK1E	P49674
Casein kinase I isoform gamma-3	CSNK1G3	Q9Y6M4
Mixed lineage kinase domain-like protein	MLKL	Q8NB16
AP2-associated protein kinase 1	AAK1	Q2M2I8
TRAF2 and NCK interacting kinase (TRAF2 and NCK interacting kinase, isoform CRA_g)	TNIK	Q9UKE5
PASK protein	PASK	Q96RG2
HCG1641087	TSSK2	A0ZT99
Dual serine/threonine and tyrosine protein kinase	DSTYK	Q6XUX3
Cyclin-G-associated kinase	GAK	O14976
Serine/threonine-protein kinase ULK3	ULK3	Q6PHR2
SFRS protein kinase 3	SRPK3	Q9UPE1
Homeodomain-interacting protein kinase 2	HIPK2	Q9H2X6
Myosin light chain kinase family member 4	MYLK4	Q86YV6
Interleukin-1 receptor-associated kinase-like 2	IRAK2	O43187
Serine/threonine-protein kinase SBK1	SBK1	Q52WX2
LIM domain kinase 2	LIMK2	P53671
Eukaryotic translation initiation factor 2-alpha kinase 4	EIF2AK4	Q9P2K8
Interleukin-1 receptor associated kinase-4	IRAK4	Q69FE3
Putative uncharacterized protein VRK3	VRK3	Q8IV63
Serine/threonine-protein kinase TAO3	TAOK3	Q9H2K8
Putative uncharacterized protein DKFZp547K1617 (Casein kinase 1, gamma 1) (HCG2004507, isoform CRA_a)	DKFZp547K1617	Q9HCP0
Protein kinase	dik	Q9H4D1
E3 ubiquitin-protein ligase RFWD3	RFWD3	Q6PCD5
Putative uncharacterized protein BMP2K	BMP2K	Q4W5H2
TAO kinase 1 (TAO kinase 1, isoform CRA_a)	TAOK1	Q7L7X3
Putative uncharacterized protein RPS6KA1	RPS6KA1	A6NND1
Putative uncharacterized protein WNK2	WNK2	A8MQ23
Aurora/Ipl1-related kinase 3 transcript variant 1	AURKC	Q9UQB9
Cell division cycle 7-related protein kinase	CDC7	O00311
Testis-specific serine kinase 1	TSSK1	A0ZT98
Serine/threonine kinase 24 (STE20 homolog, yeast)	STK24	Q5U0E6
Microtubule-associated serine/threonine-protein kinase-like	MASTL	Q96GX5
Serine/threonine-protein kinase H2	PSKH2	Q96QS6
Receptor-interacting serine/threonine-protein kinase 1	RIPK1	Q13546
U4/U6 small nuclear ribonucleoprotein Prp4	PRPF4	O43172
TAOK2 protein	TAOK2	A0PJ48
Eukaryotic translation initiation factor 2-alpha kinase 3	EIF2AK3	Q9NZJ5
Serine/threonine-protein kinase ULK2	ULK2	Q8IYT8
STE20-like serine/threonine-protein kinase	SLK	Q9H2G2
Pyruvate dehydrogenase kinase, isoenzyme 4	PDK4	A4D1H4
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	IKBKE	Q14164
Serine/threonine-protein kinase N3	PKN3	Q6P5Z2
Cyclin-dependent kinase 6	CDK6	A4D1G0
Cell division protein kinase 20	CDK20	Q8IZL9
Cyclin-dependent kinase-like 4	CDKL4	Q5MAI5
Cyclin-dependent kinase-like 3	CDKL3	Q8IVW4
PFTAIRE protein kinase 1 (PFTAIRE protein kinase 1, isoform CRA_c) (cDNA FLJ75582, highly similar to Homo sapiens PFTAIRE protein kinase 1 (PFTK1), mRNA)	PFTK1	O94921
MAPK/MAK/MRK overlapping kinase	RAGE	Q9UQ07
Mitogen-activated protein kinase 15	MAPK15	Q8TD08
Mitogen-activated protein kinase 4	MAPK4	A1A4C4
Tau-tubulin kinase 2	TTBK2	Q6IQ55
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	DYRK1A	Q13627
Lymphokine-activated killer T-cell-originated protein kinase	PBK	Q96KB5
Mitogen-activated protein kinase kinase 1	MAP2K1	A4QPA9
Dual specificity mitogen-activated protein kinase kinase 2	MAP2K2	P36507
Casein kinase 2 beta polypeptide	CSNK2B	P67870
V-akt murine thymoma viral oncogene homolog 1	AKT1	B0LPE5
WNK lysine deficient protein kinase 4	WNK4	B0LPI0
Protein kinase, cAMP-dependent, catalytic, beta, isoform CRA_a	PRKACB	B2RB89
Cyclin-dependent kinase-like 2	CDKL2	Q92772
Serine/threonine-protein kinase LMTK2	LMTK2	Q8IWU2
Ribosomal protein S6 kinase beta-2	RPS6KB2	Q9UBS0
Casein kinase I isoform gamma-2	CSNK1G2	P78368
MAP kinase-activated protein kinase 3	MAPKAPK3	Q16644
P2Y purinoceptor 12	P2RY12	Q9H244
Poly(ADP-ribose) glycohydrolase	PARG	Q86W56
Nucleoside diphosphate kinase	NME4	A2IDD0

Pathways

Name	SMPDB Link	KEGG Link
Amino Sugar Metabolism	SMP00045	map00520
Ammonia Recycling	SMP00009	map00910
Citric Acid Cycle	SMP00057	map00020
Folate Metabolism	SMP00053	map00670
Gluconeogenesis	SMP00128	map00010
Glycerolipid Metabolism	SMP00039	map00561
Glycine and Serine Metabolism	SMP00004	map00260
Glycolysis	SMP00040	map00010
Histidine Metabolism	SMP00044	map00340
Inositol Phosphate Metabolism	SMP00462	map00562
Lactose Degradation	SMP00457	Not Available
Lactose Synthesis	SMP00444	Not Available
Mitochondrial Electron Transport Chain	SMP00355	map00190
Phosphatidylinositol Phosphate Metabolism	SMP00463	map00562
Phytanic Acid Peroxisomal Oxidation	SMP00450	Not Available
Purine Metabolism	SMP00050	map00230
Threonine and 2-Oxobutanoate Degradation	SMP00452	Not Available
Transfer of Acetyl Groups into Mitochondria	SMP00466	Not Available
Trehalose Degradation	SMP00467	Not Available
Urea Cycle	SMP00059	map00330