Record Information
Version1.0
Creation date2011-09-21 00:04:17 UTC
Update date2020-09-17 15:38:09 UTC
Primary IDFDB021871
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameDeoxycytidine
DescriptionDeoxycytidine, also known as dC, belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleosides. Pyrimidine 2'-deoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. Deoxycytidine is an extremely weak basic (essentially neutral) compound (based on its pKa). Deoxycytidine exists in all living species, ranging from bacteria to humans. Within humans, deoxycytidine participates in a number of enzymatic reactions. In particular, deoxycytidine can be biosynthesized from dCMP; which is mediated by the enzyme cytosolic purine 5'-nucleotidase. In addition, deoxycytidine can be converted into dCMP through its interaction with the enzyme uridine-cytidine kinase-like 1. In humans, deoxycytidine is involved in the metabolic disorder called the beta-ureidopropionase deficiency pathway. Outside of the human body, Deoxycytidine has been detected, but not quantified in, several different foods, such as common sages, greenthread tea, chinese broccoli, oil palms, and lingonberries. This could make deoxycytidine a potential biomarker for the consumption of these foods. A pyrimidine 2'-deoxyribonucleoside having cytosine as the nucleobase.
CAS Number951-77-9
Structure
Thumb
Synonyms
SynonymSource
1-(2-Deoxy-b-D-ribofuranosyl)cytosinehmdb
1-(2-deoxy-beta-D-erythro-pentofuranosyl)-Cytosinehmdb
1-(2-Deoxy-beta-D-ribofuranosyl)cytosinehmdb
1-(2-deoxy-beta-delta-erythro-pentofuranosyl)-Cytosinehmdb
1-(2-Deoxy-beta-delta-ribofuranosyl)cytosinehmdb
2-deoxy-Cytidinehmdb
2'-Deoxycytidinehmdb
4-Amino-1-(2-deoxy-b-D-erythro-pentofuranosyl)-2(1H)-pyrimidinonehmdb
4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-2(1H)-pyrimidinonehmdb
4-Amino-1-(2-deoxy-beta-delta-erythro-pentofuranosyl)-2(1H)-pyrimidinonehmdb
4-amino-1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-oneChEBI
Cytosine deoxyribonucleosidehmdb
Cytosine deoxyribosidehmdb
dCChEBI
DCYDChEBI
deoxy-Cytidinehmdb
Deoxyribose cytidinehmdb
Desoxycytidinehmdb
Predicted PropertiesNot Available
Chemical FormulaC9H13N3O4
IUPAC name
InChI IdentifierInChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1
InChI KeyCKTSBUTUHBMZGZ-SHYZEUOFSA-N
Isomeric SMILESNC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1
Average Molecular Weight227.2172
Monoisotopic Molecular Weight227.090605919
Classification
ClassificationNot classified
Ontology
Disposition

Route of exposure:

Source:

Biological location:

Role

Industrial application:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateSolid
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
EI-MS/GC-MSNot Available
MS/MSNot Available
NMRNot Available
ChemSpider ID13117
ChEMBL IDCHEMBL66115
KEGG Compound IDC00881
Pubchem Compound ID13711
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB00014
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG ID36280
KNApSAcK IDNot Available
HET IDDCZ
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDDeoxycytidine
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
Enzymes
NameGene NameUniProt ID
Deoxycytidine kinaseDCKP27707
Cytosolic 5'-nucleotidase 3NT5C3Q9H0P0
AIDAIDQ546Y9
Uridine-cytidine kinase-like 1UCKL1Q9NWZ5
Pathways
NameSMPDB LinkKEGG Link
Pyrimidine MetabolismSMP00046 map00240
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSshow
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference