1.0 2011-09-21 00:05:41 UTC 2015-07-21 06:56:54 UTC FDB021948 16-Oxoandrostenediol 16-Oxoandrostenediol is a naturally occurring androgenic steroid hormone generated by the adrenal glands. It has been found in the urine of newborn infants. Secretion of this steroid is suppressed by dexamethasone. Levels of this hormone are almost absent by 5 months of age. ((Steroids (1964), 3(1), 77-83.) ) 16-Oxoandrostenediol is a natural hormone with androgenic activity and that two potent antiandrogens: hydroxyflutamide (Eulexin) and bicalutamide (Casodex). [HMDB] (3b,17b)-3b,17b-Dihydroxyandrost-5-en-16-one 16-Oxoandrostenediol 3b,17b-dihydroxy-Androst-5-en-16-one 3b,17b-Dihydroxyandrost-5-en-16-one 3beta,17beta-dihydroxy-Androst-5-en-16-one 5-Androsten-3b,17b-diol-16-one Androst-5-ene-3b,17b-diol-16-one C19H28O3 304.4238 304.203844762 (2R,5S,14R,15S)-5,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-13-one 5-androsten-3b,17b-diol-16-one 1159-66-6 C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C1CC(=O)[C@@H]2O InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h3,12-15,17,20,22H,4-10H2,1-2H3/t12-,13?,14?,15?,17-,18-,19-/m0/s1 AKRBLZKRYPEVIK-IACDPKRHSA-N belongs to the class of organic compounds known as androgens and derivatives. These are 3-hydroxylated C19 steroid hormones. They are known to favor the development of masculine characteristics. They also show profound effects on scalp and body hair in humans. Androgens and derivatives Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Androstane steroids Aliphatic homopolycyclic compounds 16-oxosteroids 17-hydroxysteroids 3-beta-hydroxy delta-5-steroids 3-beta-hydroxysteroids Cyclic alcohols and derivatives Cyclic ketones Delta-5-steroids Hydrocarbon derivatives Organic oxides Secondary alcohols 16-oxosteroid 17-hydroxysteroid 3-beta-hydroxy-delta-5-steroid 3-beta-hydroxysteroid 3-hydroxy-delta-5-steroid 3-hydroxysteroid Alcohol Aliphatic homopolycyclic compound Androgen-skeleton Carbonyl group Cyclic alcohol Cyclic ketone Delta-5-steroid Hydrocarbon derivative Hydroxysteroid Ketone Organic oxide Organic oxygen compound Organooxygen compound Oxosteroid Secondary alcohol Solid logp 2.39 ALOGPS logs -3.39 ALOGPS solubility 1.25e-01 g/l ALOGPS logp 2.13 ChemAxon pka_strongest_acidic 12.97 ChemAxon pka_strongest_basic -1.4 ChemAxon iupac (2R,5S,14R,15S)-5,14-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-13-one ChemAxon average_mass 304.4238 ChemAxon mono_mass 304.203844762 ChemAxon smiles C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C1CC(=O)[C@@H]2O ChemAxon formula C19H28O3 ChemAxon inchi InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h3,12-15,17,20,22H,4-10H2,1-2H3/t12-,13?,14?,15?,17-,18-,19-/m0/s1 ChemAxon inchikey AKRBLZKRYPEVIK-IACDPKRHSA-N ChemAxon polar_surface_area 57.53 ChemAxon refractivity 85.95 ChemAxon polarizability 34.66 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 18927 Specdb::CMs 37430 Specdb::CMs 137408 Specdb::CMs 145142 Specdb::CMs 1058408 Specdb::CMs 1058410 Specdb::CMs 1058412 Specdb::CMs 1058414 Specdb::CMs 1058416 Specdb::CMs 1058418 Specdb::CMs 1058420 Specdb::CMs 1058422 Specdb::CMs 1058424 Specdb::CMs 1058427 Specdb::CMs 1058429 Specdb::CMs 1058431 Specdb::CMs 1058433 Specdb::CMs 1058435 Specdb::CMs 1058437 Specdb::CMs 1058439 Specdb::CMs 1058441 Specdb::MsMs 25241 Specdb::MsMs 25242 Specdb::MsMs 25243 Specdb::MsMs 31799 Specdb::MsMs 31800 Specdb::MsMs 31801 Specdb::MsMs 3058483 Specdb::MsMs 3058484 Specdb::MsMs 3058485 Specdb::MsMs 3108151 Specdb::MsMs 3108152 Specdb::MsMs 3108153 HMDB00322 Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823