1.0 2011-09-21 00:08:05 UTC 2015-07-21 06:56:58 UTC FDB022076 5,6-Dihydrouridine Dihydrouridine is a pyrimidine which is the result of adding two hydrogen atoms to a uridine. Dihydrouridine is found only in tRNA molecules. An inhibitor of nucleotide metabolism. [HMDB] 1-b-D-Ribofuranosylhydrouracil 1-beta-D-Ribofuranosylhydrouracil 1-β-D-ribofuranosylhydrouracil 3,4-Dihydrouridine 5,6-Dihydrouridine dihydro-1-b-D-ribofuranosyl-2,4(1H,3H)-Pyrimidinedione dihydro-1-beta-delta-ribofuranosyl-2,4(1H,3H)-Pyrimidinedione Dihydrouridine C9H14N2O6 246.2173 246.08518619 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione dihydrouridine 5627-05-4 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(=O)NC1=O InChI=1S/C9H14N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4,6-8,12,14-15H,1-3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1 ZPTBLXKRQACLCR-XVFCMESISA-N belongs to the class of organic compounds known as glycosylamines. Glycosylamines are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether). Glycosylamines Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Aliphatic heteromonocyclic compounds Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Hydropyrimidines Organic carbonic acids and derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Pentoses Primary alcohols Propargyl-type 1,3-dipolar organic compounds Pyrimidones Secondary alcohols Tetrahydrofurans 1,2,5,6-tetrahydropyrimidine Alcohol Aliphatic heteromonocyclic compound Azacycle Carbonic acid derivative Carbonyl group Hydrocarbon derivative Hydropyrimidine Monosaccharide N-glycosyl compound Organic 1,3-dipolar compound Organic nitrogen compound Organic oxide Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Oxacycle Pentose monosaccharide Primary alcohol Propargyl-type 1,3-dipolar organic compound Pyrimidine Pyrimidone Secondary alcohol Tetrahydrofuran uridines Solid logp -2.10 ALOGPS logs -0.03 ALOGPS solubility 2.31e+02 g/l ALOGPS logp -2.8 ChemAxon pka_strongest_acidic 11.59 ChemAxon pka_strongest_basic -3 ChemAxon iupac 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione ChemAxon average_mass 246.2173 ChemAxon mono_mass 246.08518619 ChemAxon smiles OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(=O)NC1=O ChemAxon formula C9H14N2O6 ChemAxon inchi InChI=1S/C9H14N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4,6-8,12,14-15H,1-3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1 ChemAxon inchikey ZPTBLXKRQACLCR-XVFCMESISA-N ChemAxon polar_surface_area 119.33 ChemAxon refractivity 52.34 ChemAxon polarizability 22.98 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::MsMs 79047 Specdb::MsMs 79048 Specdb::MsMs 79049 Specdb::MsMs 139545 Specdb::MsMs 139546 Specdb::MsMs 139547 Specdb::MsMs 2357787 Specdb::MsMs 2357788 Specdb::MsMs 2357789 Specdb::MsMs 2604311 Specdb::MsMs 2604312 Specdb::MsMs 2604313 Specdb::NmrOneD 6922 Specdb::NmrOneD 6923 Specdb::NmrOneD 6924 Specdb::NmrOneD 6925 Specdb::NmrOneD 6926 Specdb::NmrOneD 6927 Specdb::NmrOneD 6928 Specdb::NmrOneD 6929 Specdb::NmrOneD 6930 Specdb::NmrOneD 6931 Specdb::NmrOneD 6932 Specdb::NmrOneD 6933 Specdb::NmrOneD 6934 Specdb::NmrOneD 6935 Specdb::NmrOneD 6936 Specdb::NmrOneD 6937 Specdb::NmrOneD 6938 Specdb::NmrOneD 6939 Specdb::NmrOneD 6940 Specdb::NmrOneD 6941 Specdb::CMs 9997 Specdb::CMs 37571 Specdb::CMs 136540 Specdb::CMs 144274 Specdb::CMs 1064112 Specdb::CMs 1064114 Specdb::CMs 1064116 Specdb::CMs 1064118 Specdb::CMs 1064120 Specdb::CMs 1064121 Specdb::CMs 1064123 Specdb::CMs 1064125 Specdb::CMs 1064127 Specdb::CMs 1064129 Specdb::CMs 1064131 Specdb::CMs 1064133 Specdb::CMs 1064134 Specdb::CMs 1064136 Specdb::CMs 1064138 Specdb::CMs 1064140 Specdb::CMs 1064141 Specdb::CMs 1064143 Specdb::CMs 1064145 Specdb::CMs 1064147 Specdb::CMs 1064149 HMDB00497 #<Reference:0x000055ce32524800> #<Reference:0x000055ce32524648> #<Reference:0x000055ce32524490> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Dihydrouridine synthase 4-like (S. cerevisiae), isoform CRA_c A4D0R5 PP35