1.0 2011-09-21 00:09:11 UTC 2025-11-19 02:40:57 UTC FDB022148 Dodecanedioic acid Dodecanedioic acid is a dicarboxylic acid which is water soluble and involves in a metabolic pathway intermediate to those of lipids and carbohydrates. (PMID 9591306). Dodecanedioid acid is an indicator of hepatic carnitine palmitoyltransferase I (CPT IA) deficiency. CPT IA deficiency is characterized by hypoketotic dicarboxylic aciduria with high urinary levels of dodecanedioic acid. This C12 dicarboxylic aciduria suggests that carnitine palmitoyltransferase I may play a role in the uptake of long-chain dicarboxylic acids by mitochondria after their initial shortening by beta-oxidation in peroxisomes. (PMID: 16146704) [HMDB] 1,10-Decanedicarboxylate 1,10-Decanedicarboxylic acid 1,10-Dicarboxydecane 1,12-Dodecanedioate 1,12-Dodecanedioic acid Corfree M 2 Decamethylenedicarboxylate Decamethylenedicarboxylic acid Dodecanedioate n-Dodecane-a,w-dioate n-Dodecane-a,w-dioic acid n-Dodecanedioate n-Dodecanedioic acid SL-AH C12H22O4 230.3007 230.151809192 dodecanedioic acid dodecanedioic acid 693-23-2 OC(=O)CCCCCCCCCCC(O)=O InChI=1S/C12H22O4/c13-11(14)9-7-5-3-1-2-4-6-8-10-12(15)16/h1-10H2,(H,13,14)(H,15,16) TVIDDXQYHWJXFK-UHFFFAOYSA-N belongs to the class of organic compounds known as medium-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. Medium-chain fatty acids Organic compounds Lipids and lipid-like molecules Fatty Acyls Fatty acids and conjugates Aliphatic acyclic compounds Carbonyl compounds Carboxylic acids Dicarboxylic acids and derivatives Hydrocarbon derivatives Organic oxides Aliphatic acyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Dicarboxylic acid or derivatives Hydrocarbon derivative Medium-chain fatty acid Organic oxide Organic oxygen compound Organooxygen compound Dicarboxylic acids Dicarboxylic acids alpha,omega-dicarboxylic acid an &alpha; &omega; dicarboxylate Solid logp 2.86 ALOGPS logs -2.90 ALOGPS solubility 2.89e-01 g/l ALOGPS logp 3.16 ChemAxon pka_strongest_acidic 4.65 ChemAxon iupac dodecanedioic acid ChemAxon average_mass 230.3007 ChemAxon mono_mass 230.151809192 ChemAxon smiles OC(=O)CCCCCCCCCCC(O)=O ChemAxon formula C12H22O4 ChemAxon inchi InChI=1S/C12H22O4/c13-11(14)9-7-5-3-1-2-4-6-8-10-12(15)16/h1-10H2,(H,13,14)(H,15,16) ChemAxon inchikey TVIDDXQYHWJXFK-UHFFFAOYSA-N ChemAxon polar_surface_area 74.6 ChemAxon refractivity 60.34 ChemAxon polarizability 26.85 ChemAxon rotatable_bond_count 11 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon Specdb::NmrOneD 1441 Specdb::NmrTwoD 1386 Specdb::CMs 26170 Specdb::CMs 37656 Specdb::CMs 174822 Specdb::CMs 1070439 Specdb::CMs 1070441 Specdb::CMs 1070443 Specdb::MsMs 846 Specdb::MsMs 847 Specdb::MsMs 848 Specdb::MsMs 4230 Specdb::MsMs 4231 Specdb::MsMs 4232 Specdb::MsMs 4233 Specdb::MsMs 4234 Specdb::MsMs 323971 Specdb::MsMs 323972 Specdb::MsMs 323973 Specdb::MsMs 372268 Specdb::MsMs 372269 Specdb::MsMs 372270 Specdb::MsMs 437539 Specdb::MsMs 437540 Specdb::MsMs 437541 Specdb::MsMs 437542 Specdb::MsMs 437543 Specdb::MsMs 2252669 Specdb::MsMs 2254769 Specdb::MsMs 2255820 Specdb::MsMs 2256700 Specdb::MsMs 2257877 Specdb::MsMs 2258668 HMDB00623 #<Reference:0x000055ce31bcb218> #<Reference:0x000055ce31bcb060> #<Reference:0x000055ce31bcaea8> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823