1.0 2011-09-21 00:11:45 UTC 2019-11-26 03:21:02 UTC FDB022299 CE(16:0) Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a combination steroid and alcohol) and a lipid found in the cell membranes of all body tissues, and transported in the blood plasma of all animals. The accumulation of cholesterol esters in the arterial intima (the innermost layer of an artery, in direct contact with the flowing blood) is a characteristic feature of atherosclerosis. Atherosclerosis is a disease affecting arterial blood vessels. It is a chronic inflammatory response in the walls of arteries, in large part to the deposition of lipoproteins (plasma proteins that carry cholesterol and triglycerides). Cholesteryl palmitate is one of the four important lipids found in the tear film. Amniotic fluid cholesteryl palmitate, as measured by thin-layer chromatography, appears to be a very sensitive and specific predictor for the risk of respiratory distress syndrome (RDS) in newborns of normal pregnancies. (PMID: 3405552, 16922549) [HMDB] (3b)-Cholest-5-en-3-ol hexadecanoate (3b)-Cholest-5-en-3-ol hexadecanoic acid (3beta)-Cholest-5-en-3-ol hexadecanoate (3beta)-Cholest-5-en-3-ol hexadecanoic acid (3β)-cholest-5-en-3-ol hexadecanoate (3β)-cholest-5-en-3-ol hexadecanoic acid 1-palmitoyl-cholesterol 16:0 Cholesterol ester cholest-5-en-3-yl palmitate Cholest-5-ene-3-beta-yl palmitate cholesterol 1-hexadecanoate cholesterol 1-hexadecanoic acid cholesterol 1-palmitoate cholesterol 1-palmitoic acid Cholesterol Ester(16:0) Cholesterol Ester(16:0/0:0) Cholesterol palmitate Cholesterol palmitic acid cholesteryl 1-hexadecanoate cholesteryl 1-hexadecanoic acid cholesteryl 1-palmitoate cholesteryl 1-palmitoic acid Cholesteryl hexadecanoate Cholesteryl hexadecanoic acid Cholesteryl palmitate Cholesteryl palmitic acid Hexadecanoate, cholesteryl ester Hexadecanoic acid Hexadecanoic acid cholesteryl ester Hexadecanoic acid, cholesteryl ester Palmitate cholesteryl ester Palmitic acid cholesteryl ester C43H76O2 625.0623 624.584531676 (1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl hexadecanoate (1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl hexadecanoate 601-34-3 [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)CCCCCCCCCCCCCCC)[C@H](C)CCCC(C)C InChI=1S/C43H76O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-23-41(44)45-36-28-30-42(5)35(32-36)24-25-37-39-27-26-38(34(4)22-20-21-33(2)3)43(39,6)31-29-40(37)42/h24,33-34,36-40H,7-23,25-32H2,1-6H3/t34-,36+,37+,38-,39+,40+,42+,43-/m1/s1 BBJQPKLGPMQWBU-JADYGXMDSA-N belongs to the class of organic compounds known as cholesteryl esters. Cholesteryl esters are compounds containing an esterified cholestane moiety. Cholesteryl esters Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Steroid esters Aliphatic homopolycyclic compounds Carbonyl compounds Carboxylic acid esters Cholesterols and derivatives Delta-5-steroids Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Aliphatic homopolycyclic compound Carbonyl group Carboxylic acid derivative Carboxylic acid ester Cholestane-skeleton Cholesterol Cholesteryl ester Delta-5-steroid Hydrocarbon derivative Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Cholesteryl esters Steryl esters cholesterol ester Solid logp 10.57 ALOGPS logs -7.96 ALOGPS solubility 6.89e-06 g/l ALOGPS logp 14.03 ChemAxon pka_strongest_basic -7 ChemAxon iupac (1S,2R,5S,10S,11S,14R,15R)-2,15-dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-yl hexadecanoate ChemAxon average_mass 625.0623 ChemAxon mono_mass 624.584531676 ChemAxon smiles [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)CCCCCCCCCCCCCCC)[C@H](C)CCCC(C)C ChemAxon formula C43H76O2 ChemAxon inchi InChI=1S/C43H76O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-23-41(44)45-36-28-30-42(5)35(32-36)24-25-37-39-27-26-38(34(4)22-20-21-33(2)3)43(39,6)31-29-40(37)42/h24,33-34,36-40H,7-23,25-32H2,1-6H3/t34-,36+,37+,38-,39+,40+,42+,43-/m1/s1 ChemAxon inchikey BBJQPKLGPMQWBU-JADYGXMDSA-N ChemAxon polar_surface_area 26.3 ChemAxon refractivity 194.21 ChemAxon polarizability 85.25 ChemAxon rotatable_bond_count 21 ChemAxon acceptor_count 1 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::NmrTwoD 1526 Specdb::NmrOneD 1584 Specdb::NmrOneD 4503 Specdb::NmrOneD 4629 Specdb::NmrOneD 5140 Specdb::NmrOneD 5141 Specdb::MsMs 182634 Specdb::MsMs 182635 Specdb::MsMs 182636 Specdb::MsMs 182982 Specdb::MsMs 182983 Specdb::MsMs 182984 Specdb::MsMs 2835447 Specdb::MsMs 2835448 Specdb::MsMs 2835449 Specdb::MsMs 2873180 Specdb::MsMs 2873181 Specdb::MsMs 2873182 HMDB00885 #<Reference:0x000055ce32cf47d8> #<Reference:0x000055ce32cf44e0> #<Reference:0x000055ce32cf4328> #<Reference:0x000055ce32cf4170> #<Reference:0x000055ce32cebf48> #<Reference:0x000055ce32cebc28> #<Reference:0x000055ce32ceb958> #<Reference:0x000055ce32ceb6b0> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Milk (Cow) Type 2 specific 6.05 8.7 2.4 uM Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Liver carboxylesterase 1 P23141 CES1 Lysosomal acid lipase/cholesteryl ester hydrolase P38571 LIPA Neutral cholesterol ester hydrolase 1 Q6PIU2 NCEH1 Phosphatidylcholine-sterol acyltransferase P04180 LCAT Scavenger receptor class B member 1 Q8WTV0 SCARB1 Sterol O-acyltransferase 1 P35610 SOAT1 Sterol O-acyltransferase 2 O75908 SOAT2