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Showing Compound Deoxyadenosine monophosphate (FDB022311)

Record Information
Version1.0
Creation date2011-09-21 00:11:56 UTC
Update date2020-09-17 15:38:44 UTC
Primary IDFDB022311
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameDeoxyadenosine monophosphate
DescriptionDeoxyadenosine monophosphate, also known as deoxyadenylic acid or 2'-dAMP, belongs to the class of organic compounds known as purine 2'-deoxyribonucleoside monophosphates. These are purine nucleotides with monophosphate group linked to the ribose moiety lacking a hydroxyl group at position 2. Deoxyadenosine monophosphate is a strong basic compound (based on its pKa). Deoxyadenosine monophosphate exists in all living species, ranging from bacteria to humans. Within humans, deoxyadenosine monophosphate participates in a number of enzymatic reactions. In particular, deoxyadenosine monophosphate can be converted into dADP through the action of the enzyme adenylate kinase isoenzyme 1. In addition, deoxyadenosine monophosphate can be converted into deoxyadenosine; which is mediated by the enzyme cytosolic purine 5'-nucleotidase. In humans, deoxyadenosine monophosphate is involved in the metabolic disorder called the gout or kelley-seegmiller syndrome pathway. A purine 2'-deoxyribonucleoside 5'-monophosphate having adenine as the nucleobase.
CAS Number653-63-4
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
SynonymSource
2'-dAMPChEBI
2'-Deoxy-5'-adenosine monophosphateChEBI
2'-Deoxy-AMPChEBI
2'-Deoxyadenosine 5'-(dihydrogen phosphate)ChEBI
2'-Deoxyadenosine 5'-phosphateChEBI
2'-Deoxyadenosine monophosphateChEBI
2'-DEOXYADENOSINE-5'-monophosphATEChEBI
2'-Deoxyadenylic acidChEBI
dAMPChEBI
Deoxy-5'-adenylic acidChEBI
Deoxy-AMPChEBI
Deoxyadenosine 5'-monophosphateChEBI
Deoxyadenosine 5'-phosphateChEBI
Deoxyadenylic acidChEBI
2'-Deoxyadenosine 5'-monophosphateKegg
2'-Deoxy-5'-adenosine monophosphoric acidGenerator
2'-Deoxyadenosine 5'-(dihydrogen phosphoric acid)Generator
2'-Deoxyadenosine 5'-phosphoric acidGenerator
2'-Deoxyadenosine monophosphoric acidGenerator
2'-DEOXYADENOSINE-5'-monophosphoric acidGenerator
2'-DeoxyadenylateGenerator
Deoxy-5'-adenylateGenerator
Deoxyadenosine 5'-monophosphoric acidGenerator
Deoxyadenosine 5'-phosphoric acidGenerator
DeoxyadenylateGenerator
2'-Deoxyadenosine 5'-monophosphoric acidGenerator
Deoxyadenosine monophosphoric acidGenerator
2'-Deoxy-5'-adenylateHMDB
2'-Deoxy-5'-adenylic acidHMDB
2'-Deoxy-adenosine 5'-phosphorateHMDB
2'-Deoxy-adenosine 5'-phosphoric acidHMDB
2'-Deoxyadenosine-5'-phosphateHMDB
Deoxyadenosine-phosphateHMDB
PdAHMDB
2'-Deoxy-5'-adenosine monophosphate, ammonium saltHMDB
2'-Deoxy-5'-adenosine monophosphate, disodium saltHMDB
2'Deoxy-5'-AMPHMDB
dAMP CPDHMDB
2'-Deoxy-5'-adenosine monoateChEBI
2'-Deoxy-5'-adenosine monoic acidGenerator
2'-Deoxy-adenosine 5'-orateHMDB
2'-Deoxy-adenosine 5'-oric acidHMDB
2'-deoxy-Adenosine 5'-phosphoratehmdb
2'-deoxy-Adenosine 5'-phosphoric acidhmdb
2'-Deoxyadenosine 5'-(dihydrogen ate)ChEBI
2'-Deoxyadenosine 5'-(dihydrogen ic acid)Generator
2'-Deoxyadenosine 5'-ateChEBI
2'-Deoxyadenosine 5'-ic acidGenerator
2'-Deoxyadenosine 5'-monoateChEBI
2'-Deoxyadenosine 5'-monoic acidGenerator
2'-Deoxyadenosine monoateChEBI
2'-Deoxyadenosine monoic acidGenerator
2'-Deoxyadenosine-5'-ateHMDB
2'-DEOXYADENOSINE-5'-monoATEChEBI
2'-DEOXYADENOSINE-5'-monoic acidGenerator
2'-deoxyadenosine-5'-monophosphatehmdb
2'-deoxyadenosine-5'-phosphatehmdb
DAMPhmdb
Deoxyadenosine 5'-ateChEBI
Deoxyadenosine 5'-ic acidGenerator
Deoxyadenosine 5'-monoateChEBI
Deoxyadenosine 5'-monoic acidGenerator
Deoxyadenosine monoateChEBI
Deoxyadenosine monoic acidGenerator
Deoxyadenosine monophosphatehmdb
Deoxyadenosine-ateHMDB
deoxyadenosine-phosphatehmdb
Predicted Properties
PropertyValueSource
Water Solubility2.71 g/LALOGPS
logP-2.4ALOGPS
logP-3.8ChemAxon
logS-2.1ALOGPS
pKa (Strongest Acidic)1.23ChemAxon
pKa (Strongest Basic)3.94ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count9ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area165.84 ŲChemAxon
Rotatable Bond Count4ChemAxon
Refractivity72.56 m³·mol⁻¹ChemAxon
Polarizability28.98 ųChemAxon
Number of Rings3ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Chemical FormulaC10H14N5O6P
IUPAC name{[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
InChI IdentifierInChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1
InChI KeyKHWCHTKSEGGWEX-RRKCRQDMSA-N
Isomeric SMILESNC1=NC=NC2=C1N=CN2[C@H]1C[C@H](O)[C@@H](COP(O)(O)=O)O1
Average Molecular Weight331.2218
Monoisotopic Molecular Weight331.068169717
Classification
Description Belongs to the class of organic compounds known as purine 2'-deoxyribonucleoside monophosphates. These are purine nucleotides with monophosphate group linked to the ribose moiety lacking a hydroxyl group at position 2.
KingdomOrganic compounds
Super ClassNucleosides, nucleotides, and analogues
ClassPurine nucleotides
Sub ClassPurine deoxyribonucleotides
Direct ParentPurine 2'-deoxyribonucleoside monophosphates
Alternative Parents
Substituents
  • Purine 2'-deoxyribonucleoside monophosphate
  • 6-aminopurine
  • Imidazopyrimidine
  • Purine
  • Aminopyrimidine
  • Monoalkyl phosphate
  • N-substituted imidazole
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Pyrimidine
  • Imidolactam
  • Alkyl phosphate
  • Azole
  • Imidazole
  • Heteroaromatic compound
  • Tetrahydrofuran
  • Secondary alcohol
  • Azacycle
  • Oxacycle
  • Organoheterocyclic compound
  • Organic oxygen compound
  • Primary amine
  • Organooxygen compound
  • Organonitrogen compound
  • Amine
  • Organic nitrogen compound
  • Organic oxide
  • Organopnictogen compound
  • Alcohol
  • Hydrocarbon derivative
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Ontology
Disposition

Source:

Biological location:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateSolid
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
EI-MS/GC-MS
TypeDescriptionSplash KeyView
GC-MSDeoxyadenosine monophosphate, 6 TMS, GC-MS Spectrumsplash10-001i-9210000000-52089369f69d88f5ea1cSpectrum
GC-MSDeoxyadenosine monophosphate, non-derivatized, GC-MS Spectrumsplash10-001i-9210000000-52089369f69d88f5ea1cSpectrum
Predicted GC-MSDeoxyadenosine monophosphate, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positivesplash10-0005-9601000000-2ae616924ca1385b9693Spectrum
Predicted GC-MSDeoxyadenosine monophosphate, 1 TMS, Predicted GC-MS Spectrum - 70eV, Positivesplash10-01ow-9433000000-7d0506e58e284d44779cSpectrum
Predicted GC-MSDeoxyadenosine monophosphate, non-derivatized, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSDeoxyadenosine monophosphate, non-derivatized, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSDeoxyadenosine monophosphate, TMS_1_2, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSDeoxyadenosine monophosphate, TMS_1_3, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSDeoxyadenosine monophosphate, TBDMS_1_1, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSDeoxyadenosine monophosphate, TBDMS_1_2, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
Predicted GC-MSDeoxyadenosine monophosphate, TBDMS_1_3, Predicted GC-MS Spectrum - 70eV, PositiveNot AvailableSpectrum
MS/MS
TypeDescriptionSplash KeyView
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-0089-4096000000-d903c4b1613b2ac5f7082012-07-24View Spectrum
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-001i-9010000000-c50cec0a2ca71d42d5242012-07-24View Spectrum
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-001i-9300000000-8ebf385d33982fcaef9f2012-07-24View Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positivesplash10-001i-0209000000-05ded3b31c4db3d6c0162012-08-31View Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) 30V, Positivesplash10-0019-1907000000-50567fa8c2638c9e2b6f2012-08-31View Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negativesplash10-003r-9804000000-9196bd87057cc65827a32012-08-31View Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF , negativesplash10-003r-9804000000-9196bd87057cc65827a32017-09-14View Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF , positivesplash10-001i-0209000000-05ded3b31c4db3d6c0162017-09-14View Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF , positivesplash10-0019-1907000000-50567fa8c2638c9e2b6f2017-09-14View Spectrum
MS/MSLC-MS/MS Spectrum - 35V, Positivesplash10-000i-2900000000-7eab9e6d466f6f6fc5ca2021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 30V, Positivesplash10-0019-1907000000-50567fa8c2638c9e2b6f2021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 20V, Positivesplash10-0019-4900000000-7e54c832e11165a43f062021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 40V, Positivesplash10-000i-6900000000-2a484df957d9a58803cd2021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 40V, Positivesplash10-000i-4930000000-881e3633ecf1832b39c12021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 10V, Positivesplash10-000i-0921000000-913b60e77094a1a288c92021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 10V, Positivesplash10-000i-2900000000-ee54193845dfdd45afd82021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 35V, Positivesplash10-000i-1900000000-700554bbc39a72147ed12021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 40V, Negativesplash10-0059-9500000000-f0950c77946a8c1b51122021-09-20View Spectrum
MS/MSLC-MS/MS Spectrum - 20V, Positivesplash10-000i-1930000000-a75e389060d82c5d0b7f2021-09-20View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-000i-0901000000-2d08f4128523b3afc5f32016-09-12View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-000i-0900000000-3c531326eee979b1f9a32016-09-12View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-000i-1900000000-e832807c09bda720138b2016-09-12View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-001i-6309000000-3c3e22257c611faa9f072016-09-12View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-004i-9500000000-2304362c6bf7c8e4aa492016-09-12View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-004i-9100000000-f628177d4207cc1a2c0b2016-09-12View Spectrum
NMR
TypeDescriptionView
1D NMR13C NMR Spectrum (1D, 125 MHz, H2O, experimental)Spectrum
1D NMR1H NMR Spectrum (1D, 500 MHz, H2O, experimental)Spectrum
1D NMR13C NMR Spectrum (1D, 25.16 MHz, D2O, experimental)Spectrum
1D NMR1H NMR Spectrum (1D, D2O, experimental)Spectrum
1D NMR13C NMR Spectrum (1D, 100 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 100 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 1000 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 1000 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 200 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 200 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 300 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 300 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 400 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 400 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 500 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 500 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 600 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 600 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 700 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 700 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 800 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 800 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 900 MHz, D2O, predicted)Spectrum
1D NMR1H NMR Spectrum (1D, 900 MHz, D2O, predicted)Spectrum
1D NMR13C NMR Spectrum (1D, 400 MHz, H2O, experimental)Spectrum
2D NMR[1H, 1H]-TOCSY. Unexported temporarily by An Chi on Oct 15, 2021 until json or nmrML file is generated. 2D NMR Spectrum (experimental)Spectrum
2D NMR[1H, 13C]-HSQC NMR Spectrum (2D, 400 MHz, H2O, experimental)Spectrum
ChemSpider ID12079
ChEMBL IDCHEMBL1206239
KEGG Compound IDC00360
Pubchem Compound ID12599
Pubchem Substance IDNot Available
ChEBI ID17713
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB00905
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG ID34735
KNApSAcK IDNot Available
HET IDD5M
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDDeoxyadenosine monophosphate
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
Enzymes
NameGene NameUniProt ID
Cytosolic 5'-nucleotidase 3NT5C3Q9H0P0
Adenylate kinase 2, mitochondrialAK2P54819
Adenylate kinase isoenzyme 1AK1P00568
Adenylate kinase isoenzyme 4, mitochondrialAK4P27144
Adenylate kinase 7AK7Q96M32
Pathways
NameSMPDB LinkKEGG Link
Purine MetabolismSMP00050 map00230
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSshow
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference