1.0 2011-09-21 00:12:21 UTC 2025-11-19 02:41:27 UTC FDB022333 Tetrahydrocortisol Tetrahydrocortisol is the most powerful natural angiostatic steroid. It is involved in C21-Steroid hormone metabolism pathway (KEGG). [HMDB] 2-hydroxy-1-(3,11,17-trihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-ethanone 3a,11b,17,21-tetrahydroxy-5b-pregnan-20-one 3b,11b,17,21-tetrahydroxy-5b-pregnan-20-one 3b,11b,17a,21-Tetrahydroxy-5b-pregnan-20-on 5b-Tetrahydrocortisol Dihydrocortison Tetrahydro-cortisol Tetrahydrocortisol Urocortisol C21H34O5 366.4917 366.240624198 2-hydroxy-1-[(2S,5R,14R,15S,17S)-5,14,17-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]ethan-1-one 2-hydroxy-1-[(2S,5R,14R,15S,17S)-5,14,17-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]ethanone 53-02-1 C[C@]12C[C@H](O)C3C(CCC4C[C@H](O)CC[C@]34C)C1CC[C@]2(O)C(=O)CO InChI=1S/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-16,18,22-24,26H,3-11H2,1-2H3/t12?,13-,14?,15?,16+,18?,19+,20+,21+/m1/s1 AODPIQQILQLWGS-OBRSLYEHSA-N belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone. 21-hydroxysteroids Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Hydroxysteroids Aliphatic homopolycyclic compounds 11-beta-hydroxysteroids 17-hydroxysteroids 20-oxosteroids 3-alpha-hydroxysteroids Alpha-hydroxy ketones Cyclic alcohols and derivatives Gluco/mineralocorticoids, progestogins and derivatives Hydrocarbon derivatives Organic oxides Polyols Primary alcohols Secondary alcohols Tertiary alcohols 11-beta-hydroxysteroid 11-hydroxysteroid 17-hydroxysteroid 20-oxosteroid 21-hydroxysteroid 3-alpha-hydroxysteroid 3-hydroxysteroid Alcohol Aliphatic homopolycyclic compound Alpha-hydroxy ketone Carbonyl group Cyclic alcohol Hydrocarbon derivative Ketone Organic oxide Organic oxygen compound Organooxygen compound Oxosteroid Polyol Pregnane-skeleton Primary alcohol Progestogin-skeleton Secondary alcohol Tertiary alcohol Solid logp 1.38 ALOGPS logs -2.90 ALOGPS solubility 4.66e-01 g/l ALOGPS logp 1.11 ChemAxon pka_strongest_acidic 12.58 ChemAxon pka_strongest_basic -1.4 ChemAxon iupac 2-hydroxy-1-[(2S,5R,14R,15S,17S)-5,14,17-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]ethan-1-one ChemAxon average_mass 366.4917 ChemAxon mono_mass 366.240624198 ChemAxon smiles C[C@]12C[C@H](O)C3C(CCC4C[C@H](O)CC[C@]34C)C1CC[C@]2(O)C(=O)CO ChemAxon formula C21H34O5 ChemAxon inchi InChI=1S/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-16,18,22-24,26H,3-11H2,1-2H3/t12?,13-,14?,15?,16+,18?,19+,20+,21+/m1/s1 ChemAxon inchikey AODPIQQILQLWGS-OBRSLYEHSA-N ChemAxon polar_surface_area 97.99 ChemAxon refractivity 97.6 ChemAxon polarizability 40.89 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 5 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Steroidogenesis SMP00130 map00140 Specdb::MsMs 83814 Specdb::MsMs 83815 Specdb::MsMs 83816 Specdb::MsMs 145506 Specdb::MsMs 145507 Specdb::MsMs 145508 Specdb::MsMs 2264584 Specdb::MsMs 2264585 Specdb::MsMs 2264586 Specdb::MsMs 3073728 Specdb::MsMs 3073729 Specdb::MsMs 3073730 Specdb::CMs 17304 Specdb::CMs 37859 Specdb::CMs 133155 Specdb::CMs 140889 Specdb::CMs 1082377 Specdb::CMs 1082378 Specdb::CMs 1082379 Specdb::CMs 1082380 Specdb::CMs 1082381 Specdb::CMs 1082382 Specdb::CMs 1082383 Specdb::CMs 1082384 Specdb::CMs 1082385 Specdb::CMs 1082386 Specdb::CMs 1082387 Specdb::CMs 1082388 Specdb::CMs 1082389 Specdb::CMs 1082390 Specdb::CMs 1082391 Specdb::CMs 1082392 Specdb::CMs 1082393 Specdb::CMs 1082394 Specdb::CMs 1082395 Specdb::CMs 1082396 Specdb::CMs 1082397 HMDB00949 #<Reference:0x000055ce3053aaf8> #<Reference:0x000055ce3053a940> #<Reference:0x000055ce3053a788> #<Reference:0x000055ce3053a5d0> #<Reference:0x000055ce3053a418> #<Reference:0x000055ce3053a260> #<Reference:0x000055ce3053a0a8> #<Reference:0x000055ce30539ef0> #<Reference:0x000055ce30539d38> #<Reference:0x000055ce30539b80> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823