1.0 2011-09-21 00:12:38 UTC 2025-11-19 02:41:30 UTC FDB022353 S-Adenosylmethioninamine S-Adenosylmethioninamine is a biological sulfonium compound known as the major biological methyl donor. It is also a donor of methylene groups, amino groups, ribosyl groups and aminopropyl groups (PMID 15130560). S-Adenosylmethioninamine is a prodcut of enzyme adenosylmethionine decarboxylase [EC 4.1.1.50] in methionine metabolism pathway (KEGG). [HMDB] (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium cation (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulphonium (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulphonium cation (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulphonium salt [1-(Adenin-9-yl)-1,5-dideoxy-b-D-ribofuranos-5-yl](3-aminopropyl)(methyl)sulfonium [1-(Adenin-9-yl)-1,5-dideoxy-b-D-ribofuranos-5-yl](3-aminopropyl)(methyl)sulphonium [1-(Adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl](3-aminopropyl)(methyl)sulfonium [1-(Adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl](3-aminopropyl)(methyl)sulphonium [1-(Adenin-9-yl)-1,5-dideoxy-β-D-ribofuranos-5-yl](3-aminopropyl)(methyl)sulfonium [1-(Adenin-9-yl)-1,5-dideoxy-β-D-ribofuranos-5-yl](3-aminopropyl)(methyl)sulphonium dAdoMet decarboxylated AdoMet decarboxylated S-adenosylmethionine decarboxylated SAM S--Adenosylmethioninamine S-Adenosyl-(5')-3-methylthiopropylamine S-Adenosyl-3-methylthiopropylamine S-Adenosyl-L-methioninamine S-adenosylmethioninamine C14H23N6O3S 355.436 355.155234322 {[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(3-aminopropyl)methylsulfanium decarboxylated sam 22365-13-5 C[S+](CCCN)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N InChI=1S/C14H23N6O3S/c1-24(4-2-3-15)5-8-10(21)11(22)14(23-8)20-7-19-9-12(16)17-6-18-13(9)20/h6-8,10-11,14,21-22H,2-5,15H2,1H3,(H2,16,17,18)/q+1/t8-,10-,11-,14-,24?/m1/s1 ZUNBITIXDCPNSD-LSRJEVITSA-N belongs to the class of organic compounds known as 5'-deoxy-5'-thionucleosides. These are 5'-deoxyribonucleosides in which the ribose is thio-substituted at the 5'position by a S-alkyl group. 5'-deoxy-5'-thionucleosides Organic compounds Nucleosides, nucleotides, and analogues 5'-deoxyribonucleosides 5'-deoxy-5'-thionucleosides Aromatic heteropolycyclic compounds 1,2-diols 6-aminopurines Aminopyrimidines and derivatives Azacyclic compounds Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Monoalkylamines N-substituted imidazoles Organic cations Organopnictogen compounds Organosulfur compounds Oxacyclic compounds Pentoses Secondary alcohols Tetrahydrofurans 1,2-diol 5'-deoxy-5'-thionucleoside 6-aminopurine Alcohol Amine Aminopyrimidine Aromatic heteropolycyclic compound Azacycle Azole Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Imidazole Imidazopyrimidine Imidolactam Monosaccharide N-glycosyl compound N-substituted imidazole Organic cation Organic nitrogen compound Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfur compound Oxacycle Pentose monosaccharide Primary aliphatic amine Primary amine Purine Pyrimidine Secondary alcohol Tetrahydrofuran Biogenic amines adenosines sulfonium compound Solid logp 0.28 ALOGPS logs -2.49 ALOGPS solubility 1.27e+00 g/l ALOGPS logp -2.8 ChemAxon pka_strongest_acidic 12.45 ChemAxon pka_strongest_basic 10.09 ChemAxon iupac {[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(3-aminopropyl)methylsulfanium ChemAxon average_mass 355.436 ChemAxon mono_mass 355.155234322 ChemAxon smiles C[S+](CCCN)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N ChemAxon formula C14H23N6O3S ChemAxon inchi InChI=1S/C14H23N6O3S/c1-24(4-2-3-15)5-8-10(21)11(22)14(23-8)20-7-19-9-12(16)17-6-18-13(9)20/h6-8,10-11,14,21-22H,2-5,15H2,1H3,(H2,16,17,18)/q+1/t8-,10-,11-,14-,24?/m1/s1 ChemAxon inchikey ZUNBITIXDCPNSD-LSRJEVITSA-N ChemAxon polar_surface_area 145.33 ChemAxon refractivity 90.4 ChemAxon polarizability 36.97 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 8 ChemAxon donor_count 4 ChemAxon physiological_charge 2 ChemAxon formal_charge 1 ChemAxon Methionine Metabolism SMP00033 map00270 Spermidine and Spermine Biosynthesis SMP00445 Specdb::NmrOneD 8162 Specdb::NmrOneD 8163 Specdb::NmrOneD 8164 Specdb::NmrOneD 8165 Specdb::NmrOneD 8166 Specdb::NmrOneD 8167 Specdb::NmrOneD 8168 Specdb::NmrOneD 8169 Specdb::NmrOneD 8170 Specdb::NmrOneD 8171 Specdb::NmrOneD 8172 Specdb::NmrOneD 8173 Specdb::NmrOneD 8174 Specdb::NmrOneD 8175 Specdb::NmrOneD 8176 Specdb::NmrOneD 8177 Specdb::NmrOneD 8178 Specdb::NmrOneD 8179 Specdb::NmrOneD 8180 Specdb::NmrOneD 8181 Specdb::MsMs 317656 Specdb::MsMs 317657 Specdb::MsMs 317658 Specdb::MsMs 3099943 Specdb::MsMs 3099944 Specdb::MsMs 3099945 Specdb::CMs 23282 Specdb::CMs 37878 Specdb::CMs 175206 Specdb::CMs 1083099 Specdb::CMs 1083100 Specdb::CMs 1083101 Specdb::CMs 1083102 Specdb::CMs 1083103 Specdb::CMs 1083104 Specdb::CMs 1083105 Specdb::CMs 1083106 Specdb::CMs 1083107 Specdb::CMs 1083108 Specdb::CMs 1083109 Specdb::CMs 1083110 Specdb::CMs 1083111 Specdb::CMs 1083112 Specdb::CMs 1083113 Specdb::CMs 1083114 Specdb::CMs 1083115 Specdb::CMs 1083116 Specdb::CMs 1083117 Specdb::CMs 1083118 Specdb::CMs 1083119 Specdb::CMs 1083120 HMDB00988 15625 #<Reference:0x000055ce2ec60500> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823 Spermidine synthase P19623 SRM Spermine synthase P52788 SMS