Record Information
Version1.0
Creation date2011-09-21 00:12:43 UTC
Update date2020-09-17 15:41:24 UTC
Primary IDFDB022359
Secondary Accession NumbersNot Available
Chemical Information
FooDB NamedCTP
DescriptiondCTP, also known as deoxy-CTP, belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleoside triphosphates. These are pyrimidine nucleotides with a triphosphate group linked to the ribose moiety lacking a hydroxyl group at position 2. dCTP is an extremely weak basic (essentially neutral) compound (based on its pKa). dCTP exists in all living species, ranging from bacteria to humans. Within humans, dCTP participates in a number of enzymatic reactions. In particular, cytidine triphosphate and dCTP can be biosynthesized from uridine triphosphate through its interaction with the enzyme CTP synthase 1. In addition, dCTP can be biosynthesized from dCDP; which is catalyzed by the enzyme nucleoside diphosphate kinase 6. In humans, dCTP is involved in the metabolic disorder called the beta-ureidopropionase deficiency pathway. Outside of the human body, dCTP is found, on average, in the highest concentration within beers. dCTP has also been detected, but not quantified in, several different foods, such as common verbena, ryes, sorghums, white lupines, and mugworts. This could make dCTP a potential biomarker for the consumption of these foods.
CAS Number2056-98-6
Structure
Thumb
Synonyms
SynonymSource
2'-Deoxycytidine 5'-triateChEBI
2'-Deoxycytidine 5'-triic acidGenerator
2'-Deoxycytidine-5'-triateHMDB
2'-deoxycytidine-5'-triphosphatehmdb
dCTPhmdb
deoxy-CTPhmdb
Deoxycytidine 5'-triateChEBI
Deoxycytidine 5'-triic acidGenerator
Deoxycytidine triateChEBI
Deoxycytidine triic acidGenerator
Deoxycytidine-triateHMDB
deoxycytidine-triphosphatehmdb
Predicted PropertiesNot Available
Chemical FormulaC9H16N3O13P3
IUPAC name
InChI IdentifierInChI=1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
InChI KeyRGWHQCVHVJXOKC-SHYZEUOFSA-N
Isomeric SMILESNC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1
Average Molecular Weight467.1569
Monoisotopic Molecular Weight466.989597149
Classification
ClassificationNot classified
Ontology
Disposition

Route of exposure:

Source:

Biological location:

Role

Industrial application:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateSolid
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
EI-MS/GC-MSNot Available
MS/MSNot Available
NMRNot Available
ChemSpider ID58601
ChEMBL IDCHEMBL560403
KEGG Compound IDC00458
Pubchem Compound ID65091
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDNot Available
HMDB IDHMDB00998
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG ID35027
KNApSAcK IDNot Available
HET IDDCP
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDdCTP
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
Enzymes
NameGene NameUniProt ID
Uridine-cytidine kinase-like 1UCKL1Q9NWZ5
DNA polymerase alpha catalytic subunitPOLA1P09884
DNA polymerase epsilon subunit 4POLE4Q9NR33
DNA polymerase delta catalytic subunitPOLD1P28340
DNA polymerase zeta catalytic subunitREV3LO60673
DNA polymerase epsilon catalytic subunit APOLEQ07864
DNA polymerase epsilon subunit 3POLE3Q9NRF9
DNA polymerase epsilon subunit 2POLE2P56282
Myb-binding protein 1AMYBBP1AQ9BQG0
DNA polymerase thetaPOLQO75417
DNA polymerase delta subunit 3POLD3Q15054
Pathways
NameSMPDB LinkKEGG Link
Pyrimidine MetabolismSMP00046 map00240
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSNot Available
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference