1.0 2011-09-21 00:13:57 UTC 2025-11-19 02:41:41 UTC FDB022436 N-Methylformamide N-Methylformamide (NMF) is one of the two major urinary biomarkers of exposure to N,N-Dimethylformamide (DMF), a compound widely used in industries because of its extensive miscibility with water and solvents. Metabolism of NMF results in the formation of N-methylcarbamoyl adducts at the N-terminal valine and lysine in blood protein globin. (PMID: 17254560, 17254560, 16289959) [HMDB] (e)-methylimidoformic acid (z)-methylimidoformic acid C2H5NO HCONHCH3 methyl-Methanimidic acid Methylformamide Methylimidoformic acid Monomethylformamide N-formylmethylamine n-methyl Formic acid amide n-methyl-Formamide N-methyl-formic acid-amide N-methyl-formimidic acid N-monomethylformamide NMF C2H5NO 59.0672 59.037113787 N-methylformamide methylformamide 123-39-7 CNC=O InChI=1S/C2H5NO/c1-3-2-4/h2H,1H3,(H,3,4) ATHHXGZTWNVVOU-UHFFFAOYSA-N belongs to the class of organic compounds known as carboximidic acids. These are organic acids with the general formula RC(=N)-OH (R=H, organic group). Carboximidic acids Organic compounds Organic acids and derivatives Carboximidic acids and derivatives Carboximidic acids Aliphatic acyclic compounds Hydrocarbon derivatives Imines Organooxygen compounds Organopnictogen compounds Propargyl-type 1,3-dipolar organic compounds Aliphatic acyclic compound Carboximidic acid Hydrocarbon derivative Imine Organic 1,3-dipolar compound Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Propargyl-type 1,3-dipolar organic compound formamides Liquid logp -1.31 ALOGPS logs 0.83 ALOGPS solubility 3.95e+02 g/l ALOGPS logp -0.86 ChemAxon pka_strongest_acidic 16.54 ChemAxon pka_strongest_basic -0.84 ChemAxon iupac N-methylformamide ChemAxon average_mass 59.0672 ChemAxon mono_mass 59.037113787 ChemAxon smiles CNC=O ChemAxon formula C2H5NO ChemAxon inchi InChI=1S/C2H5NO/c1-3-2-4/h2H,1H3,(H,3,4) ChemAxon inchikey ATHHXGZTWNVVOU-UHFFFAOYSA-N ChemAxon polar_surface_area 29.1 ChemAxon refractivity 14.87 ChemAxon polarizability 5.76 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 1 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::CMs 10994 Specdb::CMs 28265 Specdb::CMs 99652 Specdb::CMs 169941 Specdb::MsIr 1083 Specdb::MsIr 1084 Specdb::MsIr 1085 Specdb::MsMs 52854 Specdb::MsMs 52855 Specdb::MsMs 52856 Specdb::MsMs 144054 Specdb::MsMs 144055 Specdb::MsMs 144056 Specdb::MsMs 2678956 Specdb::MsMs 2678957 Specdb::MsMs 2678958 Specdb::MsMs 3030476 Specdb::MsMs 3030477 Specdb::MsMs 3030478 Specdb::NmrOneD 8662 Specdb::NmrOneD 8663 Specdb::NmrOneD 8664 Specdb::NmrOneD 8665 Specdb::NmrOneD 8666 Specdb::NmrOneD 8667 Specdb::NmrOneD 8668 Specdb::NmrOneD 8669 Specdb::NmrOneD 8670 Specdb::NmrOneD 8671 Specdb::NmrOneD 8672 Specdb::NmrOneD 8673 Specdb::NmrOneD 8674 Specdb::NmrOneD 8675 Specdb::NmrOneD 8676 Specdb::NmrOneD 8677 Specdb::NmrOneD 8678 Specdb::NmrOneD 8679 Specdb::NmrOneD 8680 Specdb::NmrOneD 8681 HMDB01122 #<Reference:0x000055ce329d2898> #<Reference:0x000055ce329d2528> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823