1.0 2011-09-21 00:15:21 UTC 2015-07-21 06:57:15 UTC FDB022524 Glyceric acid 1,3-biphosphate 1,3-Bisphosphogylcerate (1,3BPG), also known as PGAP, is a 3-carbon organic molecule present in most, if not all living creatures. It primarily exists as a metabolic intermediate in glycolysis during respiration. 1,3BPG have been recognized as regulatory signal implicated in the control of metabolism, oxygen affinity of red cells and other cellular functions. 1,3BPG concentration in erythrocytes changes in a number of pathological conditions, such as Inherited Phosphoglycerate kinase deficiency in erythrocytes (involved in the synthesis and breakdown of 1,3 BPG). (PMID 3555887) 1,3-bisphosphoglycerate is the anion form of bisphosphoglyceric acid. It is phosphorylated at the number 1 and 3 carbons. The result of this phosphorylation gives 1,3BPG important biological properties such as the ability to phosphorylate ADP to form the energy storage molecule ATP.(wikipedia) [HMDB] 1,3-Bioglycerate 1,3-Bioglyceric acid 1,3-Biphosphoglycerate 1,3-Biphosphoglyceric acid 1,3-Bis-oglycerate 1,3-bis-phosphoglycerate 1,3-Bisoglycerate 1,3-Bisphosphoglycerate 1,3-Diateglycerate 1,3-Dioglycerate 1,3-diphosphateglycerate 1,3-Diphosphoglycerate 13-DPG 2-Hydroxy-3-(onooxy)-propanoate 2-Hydroxy-3-(onooxy)-propanoic acid 2-Hydroxy-3-(onooxy)-propanoic acid 1-anhydride with orate 2-Hydroxy-3-(onooxy)-propanoic acid 1-anhydride with oric acid 2-hydroxy-3-(phosphonooxy)-Propanoate 2-hydroxy-3-(phosphonooxy)-Propanoic acid 2-hydroxy-3-(phosphonooxy)-Propanoic acid 1-anhydride with phosphorate 2-hydroxy-3-(phosphonooxy)-Propanoic acid 1-anhydride with phosphoric acid 3-O-D-Glyceroyl ate 3-O-D-Glyceroyl-ate 3-Oglyceroyl ate 3-Oglyceroyl-ate 3-Oglyceroyl-P 3-P-glyceroyl-P 3-Phospho-D-glyceroyl phosphate 3-phospho-D-glyceroyl-phosphate 3-Phosphoglyceroyl phosphate 3-phosphoglyceroyl-P 3-phosphoglyceroyl-phosphate DPG Glycerate 1,3-biate Glycerate 1,3-Biphosphate Glycerate 1,3-bisate glycerate 1,3-bisphosphate Glycerate 1,3-diate glycerate 1,3-diphosphate Glyceric acid 1,3-biate Glyceric acid 1,3-biphosphate Glyceric acid 1,3-biphosphic acid Oglyceroyl-P P-glyceroyl-P Phosphoglyceroyl-P C3H8O10P2 266.0371 265.9592695 {[2-hydroxy-3-(phosphonooxy)propanoyl]oxy}phosphonic acid 1,3-bisphosphoglycerate 1981-49-3 OC(COP(O)(O)=O)C(=O)OP(O)(O)=O InChI=1S/C3H8O10P2/c4-2(1-12-14(6,7)8)3(5)13-15(9,10)11/h2,4H,1H2,(H2,6,7,8)(H2,9,10,11) LJQLQCAXBUHEAZ-UHFFFAOYSA-N belongs to the class of organic compounds known as acyl monophosphates. These are organic compounds containing a monophosphate linked to an acyl group. They have the general structure R-CO-P(O)(O)OH, R=H or organyl. Acyl monophosphates Organic compounds Organic acids and derivatives Organic phosphoric acids and derivatives Phosphate esters Aliphatic acyclic compounds Carbonyl compounds Carboxylic acid salts Hydrocarbon derivatives Monoalkyl phosphates Monocarboxylic acids and derivatives Monosaccharides Organic oxides Organic salts Secondary alcohols Sugar acids and derivatives Acyl monophosphate Alcohol Aliphatic acyclic compound Alkyl phosphate Carbonyl group Carboxylic acid derivative Carboxylic acid salt Glyceric_acid Hydrocarbon derivative Monoalkyl phosphate Monocarboxylic acid or derivatives Monosaccharide Organic oxide Organic oxygen compound Organic salt Organooxygen compound Secondary alcohol Solid logp -1.14 ALOGPS logs -1.44 ALOGPS solubility 9.64e+00 g/l ALOGPS logp -2.3 ChemAxon pka_strongest_acidic 1.01 ChemAxon pka_strongest_basic -4.2 ChemAxon iupac {[2-hydroxy-3-(phosphonooxy)propanoyl]oxy}phosphonic acid ChemAxon average_mass 266.0371 ChemAxon mono_mass 265.9592695 ChemAxon smiles OC(COP(O)(O)=O)C(=O)OP(O)(O)=O ChemAxon formula C3H8O10P2 ChemAxon inchi InChI=1S/C3H8O10P2/c4-2(1-12-14(6,7)8)3(5)13-15(9,10)11/h2,4H,1H2,(H2,6,7,8)(H2,9,10,11) ChemAxon inchikey LJQLQCAXBUHEAZ-UHFFFAOYSA-N ChemAxon polar_surface_area 170.82 ChemAxon refractivity 42.42 ChemAxon polarizability 18.04 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 8 ChemAxon donor_count 5 ChemAxon physiological_charge -4 ChemAxon formal_charge 0 ChemAxon Gluconeogenesis SMP00128 map00010 Glycerol Phosphate Shuttle SMP00124 Glycolysis SMP00040 map00010 Mitochondrial Electron Transport Chain SMP00355 map00190 Specdb::CMs 3117 Specdb::CMs 38003 Specdb::MsMs 25007 Specdb::MsMs 25008 Specdb::MsMs 25009 Specdb::MsMs 31565 Specdb::MsMs 31566 Specdb::MsMs 31567 Specdb::NmrOneD 246608 Specdb::NmrOneD 246609 Specdb::NmrOneD 246610 Specdb::NmrOneD 246611 Specdb::NmrOneD 246612 Specdb::NmrOneD 246613 Specdb::NmrOneD 246614 Specdb::NmrOneD 246615 Specdb::NmrOneD 246616 Specdb::NmrOneD 246617 Specdb::NmrOneD 246618 Specdb::NmrOneD 246619 Specdb::NmrOneD 246620 Specdb::NmrOneD 246621 Specdb::NmrOneD 246622 Specdb::NmrOneD 246623 Specdb::NmrOneD 246624 Specdb::NmrOneD 246625 Specdb::NmrOneD 246626 Specdb::NmrOneD 246627 HMDB01270 #<Reference:0x000055ce31e743e8> #<Reference:0x000055ce31e74230> #<Reference:0x000055ce31e74078> #<Reference:0x000055ce31e73f38> #<Reference:0x000055ce31e73d80> #<Reference:0x000055ce31e73bc8> #<Reference:0x000055ce31e73a10> #<Reference:0x000055ce31e73830> #<Reference:0x000055ce31e73678> #<Reference:0x000055ce31e734c0> #<Reference:0x000055ce31e73308> Acylphosphatase-1 P07311 ACYP1 Acylphosphatase-2 P14621 ACYP2 Bisphosphoglycerate mutase P07738 BPGM Glucose 1,6-bisphosphate synthase Q6PCE3 PGM2L1 Phosphoglycerate kinase 1 P00558 PGK1 Phosphoglycerate kinase 2 P07205 PGK2 Phosphoglycerate mutase 1 P18669 PGAM1 Phosphoglycerate mutase 2 P15259 PGAM2 Probable phosphoglycerate mutase 4 Q8N0Y7 PGAM4