1.0 2011-09-21 00:15:40 UTC 2025-11-19 02:41:56 UTC FDB022546 D-Alanine Amino acids are one of the most important molecules in living organisms, and most of them have a chiral carbon at a -position. In the higher animals, a large part of the naturally occurring amino acids is the L-form, and the stereoisomers (D-amino acids) had been believed to be rare. However, several D-amino acids have been found in mammals including humans, and their distributions, functions and origins have gradually been clarified. The D-alanine (D-Ala) amounts have also been reported to change in the case of diseases. Proteins of the frontal lobe white and gray matter of human brains, both normal and Alzheimer subjects, contain D-alanine at concentrations between 0.50 and 1.28 mumol/g of wet tissue, 50-70-times lower than the concentration of L-alanine. D-Alanine have been detected in the sera of both normal subjects and patients with renal dysfunction, and their concentrations were higher in the patients than in the normal subjects. (PMID: 16141519, 1450921, 8535409, 1426150, 1933416) [HMDB] (2R)-2-Aminopropanoate (2R)-2-Aminopropanoic acid (R)-2-Aminopropanoate (R)-2-Aminopropanoic acid (R)-Alanine D-(-)-Alanine D-2-Aminopropionate D-2-Aminopropionic acid D-a-Alanine D-a-Aminopropionate D-a-Aminopropionic acid D-Ala D-Alanin D-Alanine D-alpha-Alanine D-alpha-Aminopropionate D-alpha-Aminopropionic acid D-α-alanine D-α-aminopropionate D-α-aminopropionic acid D(-)-a -Alanine D(-)-alpha-Alanine delta-(-)-Alanine delta-2-Aminopropionic acid delta-Alanine delta-alpha-Alanine C3H7NO2 89.0932 89.047678473 (2R)-2-aminopropanoic acid D-alanine 338-69-2 C[C@@H](N)C(O)=O InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m1/s1 QNAYBMKLOCPYGJ-UWTATZPHSA-N belongs to the class of organic compounds known as alanine and derivatives. Alanine and derivatives are compounds containing alanine or a derivative thereof resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. Alanine and derivatives Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aliphatic acyclic compounds Amino acids Carbonyl compounds Carboxylic acids D-alpha-amino acids Hydrocarbon derivatives Monoalkylamines Monocarboxylic acids and derivatives Organic oxides Organopnictogen compounds Alanine or derivatives Aliphatic acyclic compound Alpha-amino acid Amine Amino acid Carbonyl group Carboxylic acid D-alpha-amino acid Hydrocarbon derivative Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine D-alpha-amino acid Other amino acids alanine Solid logp -3.05 ALOGPS logs 0.70 ALOGPS solubility 4.47e+02 g/l ALOGPS logp -2.8 ChemAxon pka_strongest_acidic 2.47 ChemAxon pka_strongest_basic 9.48 ChemAxon iupac (2R)-2-aminopropanoic acid ChemAxon average_mass 89.0932 ChemAxon mono_mass 89.047678473 ChemAxon smiles C[C@@H](N)C(O)=O ChemAxon formula C3H7NO2 ChemAxon inchi InChI=1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m1/s1 ChemAxon inchikey QNAYBMKLOCPYGJ-UWTATZPHSA-N ChemAxon polar_surface_area 63.32 ChemAxon refractivity 20.5 ChemAxon polarizability 8.54 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::NmrTwoD 1620 Specdb::CMs 2623 Specdb::CMs 38016 Specdb::CMs 148378 Specdb::NmrOneD 1679 Specdb::NmrOneD 5005 Specdb::NmrOneD 147290 Specdb::NmrOneD 147291 Specdb::NmrOneD 147292 Specdb::NmrOneD 147293 Specdb::NmrOneD 147294 Specdb::NmrOneD 147295 Specdb::NmrOneD 147296 Specdb::NmrOneD 147297 Specdb::NmrOneD 147298 Specdb::NmrOneD 147299 Specdb::NmrOneD 147300 Specdb::NmrOneD 147301 Specdb::NmrOneD 147302 Specdb::NmrOneD 147303 Specdb::NmrOneD 147304 Specdb::NmrOneD 147305 Specdb::NmrOneD 147306 Specdb::NmrOneD 147307 Specdb::NmrOneD 147308 Specdb::NmrOneD 147309 Specdb::MsMs 1510 Specdb::MsMs 1511 Specdb::MsMs 1512 Specdb::MsMs 5179 Specdb::MsMs 5180 Specdb::MsMs 5181 Specdb::MsMs 5182 Specdb::MsMs 5183 Specdb::MsMs 5184 Specdb::MsMs 5185 Specdb::MsMs 178554 Specdb::MsMs 178555 Specdb::MsMs 178556 Specdb::MsMs 180873 Specdb::MsMs 180874 Specdb::MsMs 180875 Specdb::MsMs 437094 Specdb::MsMs 437095 Specdb::MsMs 440036 Specdb::MsMs 440120 Specdb::MsMs 445521 Specdb::MsMs 445522 Specdb::MsMs 445523 Specdb::MsMs 445524 Specdb::MsMs 445525 HMDB01310 15570 DAL #<Reference:0x000055ce30785010> #<Reference:0x000055ce30784e58> #<Reference:0x000055ce30784ca0> #<Reference:0x000055ce30784ae8> #<Reference:0x000055ce307848b8> Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Beer Type 2 specific 39.335 39.335 39.335 mg/L Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823