1.0 2011-09-21 00:18:09 UTC 2019-11-26 03:21:05 UTC FDB022699 L-Norleucine An unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to methionine, however it does not contain sulfur. Aminocaproic acid works as an antifibrinolytic. It is a derivative of the amino acid lysine. It binds reversibly to the kringle domain of plasminogen and blocks the binding of plasminogen to fibrin and its activation to plasmin. [HMDB] (S)-2-amino-Hexanoate (S)-2-amino-Hexanoic acid (S)-2-Aminohexanoate (S)-2-Aminohexanoic acid (S)-Aminohexanoate (S)-Aminohexanoic acid (S)-Norleucine 2-Aminocaproate 2-Aminocaproic acid 2-Aminohexanoate 2-Aminohexanoic acid a-Aminocaproate a-Aminocaproic acid alpha-Aminocaproate alpha-Aminocaproic acid Caprine Glycoleucine L-(+)-Norleucine L-2-Aminohexanoate L-2-Aminohexanoic acid L-Aminohexanoate L-Aminohexanoic acid L-Norleucine L(+)-Norleucine Nle Norleucine α-aminocaproate α-aminocaproic acid C6H13NO2 131.1729 131.094628665 (2S)-2-aminohexanoic acid caprine 327-57-1 CCCC[C@H](N)C(O)=O InChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1 LRQKBLKVPFOOQJ-YFKPBYRVSA-N belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. L-alpha-amino acids Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Aliphatic acyclic compounds Amino acids Amino fatty acids Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Medium-chain fatty acids Monoalkylamines Monocarboxylic acids and derivatives Organic oxides Organopnictogen compounds Aliphatic acyclic compound Amine Amino acid Amino fatty acid Carbonyl group Carboxylic acid Fatty acid Fatty acyl Hydrocarbon derivative L-alpha-amino acid Medium-chain fatty acid Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine 2-aminohexanoic acid Amino fatty acids Amino fatty acids non-proteinogenic L-alpha-amino acid Solid logp -1.74 ALOGPS logs -0.17 ALOGPS solubility 8.92e+01 g/l ALOGPS logp -1.4 ChemAxon pka_strongest_acidic 2.79 ChemAxon pka_strongest_basic 9.53 ChemAxon iupac (2S)-2-aminohexanoic acid ChemAxon average_mass 131.1729 ChemAxon mono_mass 131.094628665 ChemAxon smiles CCCC[C@H](N)C(O)=O ChemAxon formula C6H13NO2 ChemAxon inchi InChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1 ChemAxon inchikey LRQKBLKVPFOOQJ-YFKPBYRVSA-N ChemAxon polar_surface_area 63.32 ChemAxon refractivity 34.22 ChemAxon polarizability 14.46 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon Specdb::NmrTwoD 1681 Specdb::MsIr 1350 Specdb::MsIr 1351 Specdb::MsIr 1352 Specdb::CMs 767 Specdb::CMs 768 Specdb::CMs 769 Specdb::CMs 770 Specdb::CMs 771 Specdb::CMs 958 Specdb::CMs 1049 Specdb::CMs 1239 Specdb::CMs 3423 Specdb::CMs 30063 Specdb::CMs 30064 Specdb::CMs 30209 Specdb::CMs 30314 Specdb::CMs 30650 Specdb::CMs 30796 Specdb::CMs 31347 Specdb::CMs 31348 Specdb::CMs 31349 Specdb::CMs 38136 Specdb::CMs 130700 Specdb::CMs 138434 Specdb::MsMs 1669 Specdb::MsMs 1670 Specdb::MsMs 1671 Specdb::MsMs 5423 Specdb::MsMs 5424 Specdb::MsMs 5425 Specdb::MsMs 5426 Specdb::MsMs 5427 Specdb::MsMs 5428 Specdb::MsMs 5429 Specdb::MsMs 5430 Specdb::MsMs 5436 Specdb::MsMs 5437 Specdb::MsMs 5438 Specdb::MsMs 180150 Specdb::MsMs 180151 Specdb::MsMs 180152 Specdb::MsMs 182484 Specdb::MsMs 182485 Specdb::MsMs 182486 Specdb::MsMs 438204 Specdb::MsMs 438205 Specdb::MsMs 438206 Specdb::MsMs 439086 Specdb::MsMs 440112 Specdb::NmrOneD 1741 Specdb::NmrOneD 5006 Specdb::NmrOneD 5007 Specdb::NmrOneD 148260 Specdb::NmrOneD 148261 Specdb::NmrOneD 148262 Specdb::NmrOneD 148263 Specdb::NmrOneD 148264 Specdb::NmrOneD 148265 Specdb::NmrOneD 148266 Specdb::NmrOneD 148267 Specdb::NmrOneD 148268 Specdb::NmrOneD 148269 Specdb::NmrOneD 148270 Specdb::NmrOneD 148271 Specdb::NmrOneD 148272 Specdb::NmrOneD 148273 Specdb::NmrOneD 148274 Specdb::NmrOneD 148275 Specdb::NmrOneD 148276 Specdb::NmrOneD 148277 Specdb::NmrOneD 148278 Specdb::NmrOneD 148279 HMDB01645 NLE Anatidae Type 1 specific Anatidae 8830 Beefalo Type 1 specific Bos taurus X Bison bison 297284 Bison Type 1 specific Bison bison 9901 Buffalo Type 1 specific Bubalus bubalis 89462 Cattle (Beef, Veal) Type 1 specific Bos taurus 9913 Chicken Type 1 specific Gallus gallus 9031 Columbidae (Dove, Pigeon) Type 1 specific Columbidae 8930 Deer Type 1 specific Cervidae 9850 Domestic goat Type 1 specific Capra aegagrus hircus 9925 Domestic pig Type 1 specific Sus scrofa domestica 9825 Elk Type 1 specific Cervus canadensis 1574408 Emu Type 1 specific Dromaius novaehollandiae 8790 European rabbit Type 1 specific Oryctolagus 9984 Greylag goose Type 1 specific Anser anser 8843 Guinea hen Type 1 specific Numida meleagris 8996 Horse Type 1 specific Equus caballus 9796 Mallard duck Type 1 specific Anas platyrhynchos 8839 Milk (Cow) Type 2 specific Mountain hare Type 1 specific Lepus timidus 62621 Mule deer Type 1 specific Odocoileus 9871 Ostrich Type 1 specific Struthio camelus 8801 Pheasant Type 1 specific Phasianus colchicus 9054 Quail Type 1 specific Phasianidae 9005 Rabbit Type 1 specific Leporidae 9979 Rock ptarmigan Type 1 specific Lagopus muta 64668 Sheep (Mutton, Lamb) Type 1 specific Ovis aries 9940 Squab Type 1 specific Columba 8931 Turkey Type 1 specific Meleagris gallopavo 9103 Velvet duck Type 1 specific Melanitta fusca 371864 Wild boar Type 1 specific Sus scrofa 9823