Record Information
Version1.0
Creation date2011-09-21 00:18:17 UTC
Update date2015-10-09 22:30:55 UTC
Primary IDFDB022708
Secondary Accession NumbersNot Available
Chemical Information
FooDB NameVerapamil
DescriptionA calcium channel blocker that is a class IV anti-arrhythmia agent. -- Pubchem; Calcium channel antagonists can be quite toxic. In the management of poisoning, early recognition is critical. Calcium channel antagonists are frequently prescribed, and the potential for serious morbidity and mortality with over dosage is significant. Ingestion of these agents should be suspected in any patient who presents in an overdose situation with unexplained hypotension and conduction abnormalities. The potential for toxicity should be noted in patients with underlying hepatic or renal dysfunction who are receiving therapeutic doses. (PMID 8213877) [HMDB]
CAS Number52-53-9
Structure
Thumb
Synonyms
SynonymSource
Akilenhmdb
Anpechmdb
Apo-Veraphmdb
Arpamyl LPhmdb
Berkatenshmdb
Calanhmdb
Calan SRhmdb
Calaptinhmdb
Calaptin 240 SRhmdb
Calcanhmdb
Cardiabeltinhmdb
Cardiagutthmdb
Cardibeltinhmdb
Cardioprotecthmdb
Caverilhmdb
Civicorhmdb
Civicor Retardhmdb
Coraverhmdb
Cordiloxhmdb
Cordilox SRhmdb
Corpamilhmdb
Covera-Hshmdb
D-365hmdb
delta-365hmdb
Dignoverhmdb
Dilacoranhmdb
Dilacoran HTAhmdb
Durasoptinhmdb
Elthonhmdb
Falicardhmdb
Finoptinhmdb
Flamonhmdb
Geanginhmdb
Hartezehmdb
Hexasoptinhmdb
Hexasoptin Retardhmdb
Hormitolhmdb
Ikacorhmdb
Ikapresshmdb
Inselonhmdb
Iproveratrilhmdb
Isoptinhmdb
Isoptin Retardhmdb
Isoptin SRhmdb
Isoptinehmdb
Isoptinohmdb
Isotopinhmdb
Izoptinhmdb
Jenapamilhmdb
Lekoptinhmdb
Lodixalhmdb
Magotironhmdb
Manidonhmdb
Manidon Retardhmdb
Novapamyl LPhmdb
Novo-Veramilhmdb
Nu-Veraphmdb
Ormilhmdb
Praecicorhmdb
Quasarhmdb
Rapamhmdb
Robatelanhmdb
Securonhmdb
Tarkahmdb
Univerhmdb
Univexhmdb
Vasolanhmdb
Vasomilhmdb
Vasoptenhmdb
Vera-Sanoraniahmdb
Verabetahmdb
Veracaps SRhmdb
Veracorhmdb
Verahexalhmdb
Veralochmdb
Veramexhmdb
Veramilhmdb
Verapamilhmdb
Verapamil Acishmdb
Verapamil ALhmdb
Verapamil Atidhmdb
Verapamil Basicshmdb
Verapamil Ebewehmdb
Verapamil hclHMDB
Verapamil Henninghmdb
Verapamil Injectionhmdb
Verapamil MSDhmdb
Verapamil NMhmdb
Verapamil NM Pharmahmdb
Verapamil Nordichmdb
Verapamil PBhmdb
Verapamil Rikerhmdb
Verapamil SRhmdb
Verapamil Verlahmdb
Verapamil-AbZhmdb
VerapamiloHMDB
VerapamilumHMDB
Verapinhmdb
Verapress 240 SRhmdb
Verasalhmdb
Verasifarhmdb
Veratensinhmdb
Verdilachmdb
Verelanhmdb
Verelan PMhmdb
Verelan SRhmdb
Veroptinstadahmdb
Verpamilhmdb
Vetrimilhmdb
Vortachmdb
Predicted PropertiesNot Available
Chemical FormulaC27H38N2O4
IUPAC name
InChI IdentifierInChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
InChI KeySGTNSNPWRIOYBX-UHFFFAOYSA-N
Isomeric SMILESCOC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
Average Molecular Weight454.6016
Monoisotopic Molecular Weight454.283157714
Classification
ClassificationNot classified
Ontology
Physiological effect

Health effect:

Disposition

Source:

Route of exposure:

Biological location:

Role

Environmental role:

Industrial application:

Physico-Chemical Properties - Experimental
Physico-Chemical Properties - Experimental
PropertyValueReference
Physical stateSolid
Physical DescriptionNot Available
Mass CompositionNot Available
Melting PointNot Available
Boiling PointNot Available
Experimental Water SolubilityNot Available
Experimental logPNot Available
Experimental pKaNot Available
Isoelectric pointNot Available
ChargeNot Available
Optical RotationNot Available
Spectroscopic UV DataNot Available
DensityNot Available
Refractive IndexNot Available
Spectra
Spectra
EI-MS/GC-MSNot Available
MS/MSNot Available
NMRNot Available
ChemSpider ID2425
ChEMBL IDCHEMBL6966
KEGG Compound IDC07188
Pubchem Compound ID2520
Pubchem Substance IDNot Available
ChEBI IDNot Available
Phenol-Explorer IDNot Available
DrugBank IDDB00661
HMDB IDHMDB01850
CRC / DFC (Dictionary of Food Compounds) IDNot Available
EAFUS IDNot Available
Dr. Duke IDNot Available
BIGG IDNot Available
KNApSAcK IDNot Available
HET IDNot Available
Food Biomarker OntologyNot Available
VMH IDNot Available
Flavornet IDNot Available
GoodScent IDNot Available
SuperScent IDNot Available
Wikipedia IDVerapamil
Phenol-Explorer Metabolite IDNot Available
Duplicate IDSNot Available
Old DFC IDSNot Available
Associated Foods
FoodContent Range AverageReference
FoodReference
Biological Effects and Interactions
Health Effects / BioactivitiesNot Available
EnzymesNot Available
PathwaysNot Available
MetabolismNot Available
BiosynthesisNot Available
Organoleptic Properties
FlavoursNot Available
Files
MSDSshow
References
Synthesis ReferenceNot Available
General ReferenceNot Available
Content Reference