1.0 2011-09-21 00:19:00 UTC 2018-05-28 18:33:54 UTC FDB022747 Ranitidine A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers. -- Pubchem; Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and commonly used in the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). It is currently marketed by GlaxoSmithKline under the trade name Zantac. -- Wikipedia [HMDB] Achedos acidex Atural Axoban Coralen Curan Duractin Ezopta Gastrial Gastrosedol Istomar Logast Mauran Microtid Ptinolin Quantor Quicran Radinat Randin Ranidine Ranin Raniogas Ranisen Raniter Ranitidina Ranitidina [INN-Spanish] Ranitidine Ranitidine (Form I And Form Ii) Ranitidine [USAN:BAN:INN] Ranitidine Base Ranitidine HCL 1/2 Type Ranitidinum Ranitidinum [INN-Latin] Ranitiget Rantacid Rantidine Ratic Raticina RND Sampep Taural Ul-Pep Ulceranin Urantac Verlost Vesyca Vizerul Weichilin Weidos Xanidine Zantab ZANTAC Zantac (TN) Zantadin C13H22N4O3S 314.404 314.14126128 dimethyl[(5-{[(2-{[(E)-1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}furan-2-yl)methyl]amine ranitidine 66357-59-3 CN\C(NCCSCC1=CC=C(CN(C)C)O1)=C/[N+]([O-])=O InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+ VMXUWOKSQNHOCA-UKTHLTGXSA-N belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group. Aralkylamines Organic compounds Organic nitrogen compounds Organonitrogen compounds Amines Aromatic heteromonocyclic compounds C-nitro compounds Dialkylamines Dialkylthioethers Furans Heteroaromatic compounds Hydrocarbon derivatives Organic oxides Organic oxoazanium compounds Organic zwitterions Organooxygen compounds Organopnictogen compounds Oxacyclic compounds Propargyl-type 1,3-dipolar organic compounds Sulfenyl compounds Trialkylamines Allyl-type 1,3-dipolar organic compound Aralkylamine Aromatic heteromonocyclic compound C-nitro compound Dialkylthioether Furan Heteroaromatic compound Hydrocarbon derivative Organic 1,3-dipolar compound Organic nitro compound Organic oxide Organic oxoazanium Organic oxygen compound Organic zwitterion Organoheterocyclic compound Organooxygen compound Organopnictogen compound Organosulfur compound Oxacycle Propargyl-type 1,3-dipolar organic compound Secondary aliphatic amine Secondary amine Sulfenyl compound Tertiary aliphatic amine Tertiary amine Thioether C-nitro compound furans tertiary amino compound Solid logp 0.79 ALOGPS logs -3.60 ALOGPS solubility 7.95e-02 g/l ALOGPS logp 0.99 ChemAxon pka_strongest_basic 7.8 ChemAxon iupac dimethyl[(5-{[(2-{[(E)-1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}furan-2-yl)methyl]amine ChemAxon average_mass 314.404 ChemAxon mono_mass 314.14126128 ChemAxon smiles CN\C(NCCSCC1=CC=C(CN(C)C)O1)=C/[N+]([O-])=O ChemAxon formula C13H22N4O3S ChemAxon inchi InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+ ChemAxon inchikey VMXUWOKSQNHOCA-UKTHLTGXSA-N ChemAxon polar_surface_area 83.58 ChemAxon refractivity 94.15 ChemAxon polarizability 33.69 ChemAxon rotatable_bond_count 10 ChemAxon acceptor_count 5 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::NmrTwoD 1749 Specdb::NmrOneD 1809 Specdb::CMs 7217 Specdb::CMs 169858 Specdb::MsMs 1869 Specdb::MsMs 1870 Specdb::MsMs 1871 Specdb::MsMs 5625 Specdb::MsMs 5626 Specdb::MsMs 5627 Specdb::MsMs 5628 Specdb::MsMs 5629 Specdb::MsMs 5630 Specdb::MsMs 5631 Specdb::MsMs 5632 Specdb::MsMs 5633 Specdb::MsMs 5634 Specdb::MsMs 5635 Specdb::MsMs 5636 Specdb::MsMs 5637 Specdb::MsMs 5638 Specdb::MsMs 5639 Specdb::MsMs 5640 Specdb::MsMs 5641 Specdb::MsMs 5642 Specdb::MsMs 252342 Specdb::MsMs 252343 Specdb::MsMs 252344 Specdb::MsMs 272283 HMDB01930 Histamine H2 receptor P25021 HRH2