1.0 2011-09-21 00:19:01 UTC 2018-05-28 18:33:54 UTC FDB022749 Metoprolol Metoprolol is a selective beta1 receptor blocker used in treatment of several diseases of the cardiovascular system. It is marketed under the brand name Lopressor by Novartis, and Toprol (in the USA); Seleken or Selokeen (elsewhere); A selective adrenergic beta-1-blocking agent with no stimulatory action. It's binding to plasma albumin is weaker than alprenolol and it may be useful in the treatment of several diseases of the cardiovascular system; Metoprolol is a selective beta1 receptor blocker used in treatment of several diseases of the cardiovascular system. It is marketed under the brand name Lopressor by Novartis, and Toprol (in the USA); Seleken or Selokeen (elsewhere); as Minax by Alphapharm (in Australia), as Betaloc by AstraZeneca and as Corvitol by Berlin-Chemie AG; A selective adrenergic beta-1-blocking agent with no stimulatory action. It's binding to plasma albumin is weaker than alprenolol and it may be useful in angina pectoris, hypertension, or cardiac arrhythmias; as Minax by Alphapharm (in Australia), as Betaloc by AstraZeneca and as Corvitol by Berlin-Chemie AG. [HMDB] (+/-)-Metoprolol (RS)-Metoprolol 1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol Beatrolol dl-Metoprolol Lopresor Lopresoretic Lopressor Meijoprolol Metohexal Metoprolol Metoprolol succinate Metoprolol tartrate Metoprololum Preblok Presolol Seloken Seroken Spesicor Toprol-XL C15H25NO3 267.3639 267.183443671 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol metoprolol 37350-58-6 COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3 IUBSYMUCCVWXPE-UHFFFAOYSA-N belongs to the class of organic compounds known as tyrosols and derivatives. Tyrosols and derivatives are compounds containing a hydroxyethyl group attached to the C4 carbon of a phenol group. Tyrosols and derivatives Organic compounds Benzenoids Phenols Tyrosols and derivatives Aromatic homomonocyclic compounds 1,2-aminoalcohols Alkyl aryl ethers Dialkyl ethers Dialkylamines Hydrocarbon derivatives Organopnictogen compounds Phenol ethers Phenoxy compounds Secondary alcohols 1,2-aminoalcohol Alcohol Alkyl aryl ether Amine Aromatic homomonocyclic compound Dialkyl ether Ether Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenol ether Phenoxy compound Secondary alcohol Secondary aliphatic amine Secondary amine Tyrosol derivative aromatic ether propanolamine secondary alcohol secondary amino compound Solid logp 1.80 ALOGPS logs -2.82 ALOGPS solubility 4.02e-01 g/l ALOGPS logp 1.76 ChemAxon pka_strongest_acidic 14.09 ChemAxon pka_strongest_basic 9.67 ChemAxon iupac 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol ChemAxon average_mass 267.3639 ChemAxon mono_mass 267.183443671 ChemAxon smiles COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 ChemAxon formula C15H25NO3 ChemAxon inchi InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3 ChemAxon inchikey IUBSYMUCCVWXPE-UHFFFAOYSA-N ChemAxon polar_surface_area 50.72 ChemAxon refractivity 76.7 ChemAxon polarizability 31.9 ChemAxon rotatable_bond_count 9 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon Specdb::NmrOneD 1810 Specdb::NmrTwoD 1750 Specdb::CMs 8773 Specdb::CMs 38190 Specdb::CMs 117906 Specdb::CMs 123897 Specdb::CMs 152903 Specdb::CMs 806621 Specdb::CMs 806622 Specdb::MsMs 1872 Specdb::MsMs 1873 Specdb::MsMs 1874 Specdb::MsMs 261720 Specdb::MsMs 261721 Specdb::MsMs 261722 Specdb::MsMs 281652 Specdb::MsMs 281653 Specdb::MsMs 281654 Specdb::MsMs 440891 Specdb::MsMs 441601 Specdb::MsMs 441602 Specdb::MsMs 441603 Specdb::MsMs 441604 Specdb::MsMs 441605 Specdb::MsMs 441606 Specdb::MsMs 441607 Specdb::MsMs 441608 Specdb::MsMs 441609 Specdb::MsMs 441610 Specdb::MsMs 441611 Specdb::MsMs 441612 Specdb::MsMs 441613 Specdb::MsMs 441614 Specdb::MsMs 444872 HMDB01932 6904 #<Reference:0x000055ce30212a88> #<Reference:0x000055ce30212858> #<Reference:0x000055ce302126a0> Beta-1 adrenergic receptor P08588 ADRB1